Lead Exposure and Multiple Sclerosis

Sponsor
Assiut University
Study ID
NCT07423312
Status
Not Yet Recruiting

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Conditions

Eligibility Criteria

Sex
ALL
Age
20 Years - 50 Years
Healthy Volunteers
Accepted

Study Details

1. To evaluate the effect of lead level on the pathogenesis of multiple sclerosis 2. Measure lead in blood sample of study groups 3. Estimate the expression level of DNA methyltransferase. 4. Evaluate oxidative stress markers, like MDA/8-OHdG 5. Measureδ-aminolevulinic acid 6. Correlate the clinical data of patients with biochemical markers

Key Dates

First listed
Feb 20, 2026
Start date
Dec 30, 2026
Status verified
Feb 2026
Primary completion
Dec 30, 2028
Completion
May 5, 2029

Study Design

Enrollment
140 participants (estimated)

Arms

  • Arm: healthy group
  • Arm: multiple sclerosis group

Primary Outcome Measure

Measure concentration of blood lead level in multiple sclerosis patients and controls, assessed with biochemical analysis [ Time Frame: 2years ]

Central Contacts

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