Pulsed Electric Field Ablation for Metastatic Breast Cancer

Part of paid clinical trials in San Francisco, California.

Sponsor
University of California, San Francisco
Study ID
NCT07487844
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Pulsed Electric Field (PEF) System — DEVICE
    Pulsed electric field (PEF) delivers short, high frequency electrical pulses that are intended to shrink or destroy tumors
  • Questionnaires — BEHAVIORAL
    Participants will complete health related, quality of life questionnaires
  • Tumor Ablation — PROCEDURE
    Undergo ablation via PEF

Study Details

This is a phase I trial of the safety of image-guided pulsed electric field (PEF) ablation for the locoregional treatment of superficial soft tissue lesions in adults with metastatic breast cancer using the AliyaTM Pulsed Electric Field System.

Key Dates

First listed
Mar 23, 2026
Start date
Jun 29, 2026
Status verified
Sep 2026
Primary completion
Aug 1, 2028
Completion
Aug 1, 2028

Study Design

Enrollment
20 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Image-Guided Pulsed Electric Field (PEF) Ablation
    Participants undergo a single treatment of PEF ablation delivered to up to 3 soft tissue metastatic breast cancer lesion(s). Ablation parameters, immediate adverse events, and post-ablation imaging will be collected during the ablation treatment.

Primary Outcome Measure

Proportion of participants with treatment-emergent adverse events [ Time Frame: Up to 4 weeks ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of California San FranciscoSan FranciscoCalifornia94143
Maya Aslam
[email protected]
877-827-3222
[email protected]
Ryan Kohlbrenner, MD (PRINCIPAL_INVESTIGATOR)

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Breast cancer
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OncologyBreast oncologyWomen's health
By research site
University of California San Francisco· San Francisco, CA

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