Oncology Clinical Trials in San Francisco, CA
As of September 2026, 257 paid clinical trials are recruiting for Oncology in San Francisco, California. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in San Francisco
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
258 clinical trials for Oncology
·Clear filters·A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)
A Study Comparing JNJ-79635322 and an Anti-B-cell Maturation Antigen (BCMA)xCD3 Bispecific Antibody in Participants With Relapsed or Refractory Multiple Myeloma
A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
Beamion LUNG-3: Adjuvant Zongertinib vs Standard Treatment in People With Completely Resected Stage II-IIIB NSCLC Harboring Activating HER2 TKD Mutations
Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer
A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL
Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)
Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects
A Study to Evaluate the Safety and Efficacy of Tacabrutideg (BGB-16673) Compared to Pirtobrutinib in Adults With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer
A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.
Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)
A Long-term Study for Participants Previously Treated With Ciltacabtagene Autoleucel
SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)
A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)
A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer
A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors
A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)
A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)
Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer
A Study to Compare the Efficacy and Safety of BMS-986365 Versus the Investigator's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer
FOG-001 in Locally Advanced or Metastatic Solid Tumors
A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer
A First-in-Human Study of MEN2312 in Adults With Advanced Breast Cancer
Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia
A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1%
Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)
Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)
A Phase 1/2 Study of Bleximenib in Participants With Acute Leukemia (cAMeLot-1)
A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations
A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer
Top Research Study Locations in San Francisco
Researchers run research studies in San Francisco, CA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of California, San Francisco | Prostate Cancer, Glioblastoma, Epilepsy | 320 |
| University of California San Francisco | Prostate Cancer, Breast Cancer, Multiple Myeloma | 166 |
| Power Life Sciences | Acne, Anorexia, Anorexia Nervosa | 51 |
| UCSF | Colorectal Cancer, ADHD, ALK-Positive Lung Cancer | 32 |
| Kaiser Permanente-San Francisco | Stage IV Lung Cancer AJCC v8, Lung Non-Small Cell Carcinoma, Recurrent Lung Non-Small Cell Carcinoma | 32 |
| UCSF Medical Center-Mission Bay | B Acute Lymphoblastic Leukemia, Neuroblastoma, Acute Myeloid Leukemia | 32 |
| Zuckerberg San Francisco General Hospital | Cardiovascular Diseases, HIV, Healthy | 26 |
| UCSF Medical Center | Stroke, Aneurysm, Aneurysm, Intracranial | 23 |
| California Pacific Medical Center-Pacific Campus | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, HER2-Negative Breast Carcinoma | 22 |
| UCSF Helen Diller Family Comprehensive Cancer Center | Advanced Breast Cancer, Breast Cancer, Solid Tumor, Adult | 21 |
| University of California | Aortic Valve Regurgitation, Aortic Valve Stenosis, Articular Cartilage | 18 |
| San Francisco VA Medical Center, San Francisco, CA | PTSD, Sleep Initiation and Maintenance Disorders, Aging | 16 |
| University of California, San Francisco (UCSF) | Colorectal Cancer, Non-small Cell Lung Cancer, Acquired Resistance to KRAS G12C Inhibitor | 15 |
| UCSF Benioff Children's Hospital | 4H Syndrome, ADLD, AGS | 14 |
| California Pacific Medical Center | Amyotrophic Lateral Sclerosis, Amyotrophic Lateral Sclerosis (ALS), Melanoma | 12 |
| San Francisco General Hospital | HIV, HIV Infections, Intracerebral Hemorrhage | 12 |
| San Francisco Research Institute | Women Health, Anxiety, Cognitive Decline | 10 |
| Alethios, Inc. | Abdominal Discomfort, Digestive Health, Digestive Well Being | 9 |
| San Francisco VA Medical Center | Atopic Dermatitis, Eczema, Atopic Dermatitis (Eczema) | 9 |
| UCSF Medical Center-Parnassus | Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm, Acute Myeloid Leukemia Post Cytotoxic Therapy | 8 |
| University of California - San Francisco | Diabetes, Diabetic Foot, Diabetic Foot Ulcer | 8 |
| University of California San Francisco (UCSF) | Melanoma, Advanced Solid Tumors, Angiosarcoma | 8 |
| University of California at San Francisco | Advanced Tumors, Aortic Valve Disease, Aortic Valve Stenosis | 8 |
| University of San Francisco | Cone Rod Dystrophy, Juvenile Macular Degeneration, Stargardt Disease | 7 |
| UCSF Medical Center at Mission Bay | Breast Cancer, Atrial Fibrillation (AF), Atrial Fibrillation (Paroxysmal) | 6 |
Active & Upcoming Studies in San Francisco (2026)
Recruiting trials in San Francisco grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (396 active studies)
- Prenatal Transplantation for Fetuses With Fanconi Anemia · Phase 1, Phase 2 · Agnieszka Czechowicz
- Quality of Life for Patients With Breast Cancer Brain Metastases and Leptomeningeal Disease · University of California, San Francisco
Neurology & pain (83 active studies)
- Alzheimer's Tau Platform: Regimen A - AADvac1 · Phase 2 · Paul S. Aisen
- An Artificial Intelligence Driven Approach to Optimize Patient Selection for a Transitional Pain Service · Phase 3 · University of California, San Francisco
Cardiovascular (82 active studies)
- Naloxone for Opioid Associated Out of Hospital Cardiac Arrest · Phase 2 · University of California, San Francisco
- A Prospective, Randomized Multicenter Clinical Trial of the TricValve® Transcatheter Bicaval Valve System in Subjects With Severe Tricuspid Regurgitation. · P+F Products + Features USA Inc.
Mental health & behavior (49 active studies)
- LIFU Effects & Outcomes: Mechanisms Evaluating Striatal Systems Imaging (LEO MESSI) · University of California, San Francisco
- Facilitating Transition to Recommended PTSD Treatment · VA Office of Research and Development
HIV / STI (48 active studies)
- Psilocybin Therapy for Methamphetamine Use Disorder and HIV · Phase 2 · Nicky Mehtani, MD, MPH
- Short-term Effects of Methamphetamine on Residual Latent HIV Disease Study · Phase 4 · University of California, San Francisco
Diabetes & metabolic (37 active studies)
- PRISE (Personalized Response and Immunologic Surveillance of Endogenous C-Peptide Preservation in New, Recent, and Established Onset Type 1 Diabetes Treated With Human Anti-Thymocyte Globulin [h-ATG]) Study · Phase 3 · University of Florida
- Safety and Efficacy of NA-931 and Tirzepatide in Adults Who Are Overweight or Obese · Phase 2 · Biomed Industries, Inc.
Pediatric (21 active studies)
- Prenatal Transplantation for Fetuses With Fanconi Anemia · Phase 1, Phase 2 · Agnieszka Czechowicz
- Music Therapy for Oral Mucositis Pain in Pediatric Patients · University of California, San Francisco
Eye & vision (19 active studies)
- Video Intervention to Improve Understanding of Diabetic Retinopathy at Zuckerberg San Francisco General Hospital and Trauma Center · University of California, San Francisco
- Effect of Vision Centers on Access to Eye Care and Eye Health Outcomes · University of California, San Francisco
Vaccines (13 active studies)
- Validation of Biomarkers for Long COVID in the LIINC Viral Immunopathogenesis and Persistence Repeat Donor Cohort (VIPER) · University of California, San Francisco
- Multiparametric [18F]F-AraG Imaging in Post-Acute Sequelae of COVID-19 (PASC) · EARLY_Phase 1 · University of California, Davis
Common conditions studied in San Francisco
- Breast Cancer (28 active studies)
- Prostate Cancer (27 active studies)
- Heart Failure (18 active studies)
- HIV (16 active studies)
- Cancer (13 active studies)
- Solid Tumor (13 active studies)
Leading research sponsors in San Francisco
- University of California, San Francisco
- Power Life Sciences Inc.
- National Cancer Institute (NCI)
- AstraZeneca
- Children's Oncology Group
Frequently asked questions
How many paid clinical trials are currently recruiting in San Francisco?
There are approximately 1,349 recruiting clinical trials in San Francisco, California listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in San Francisco pay participants?
Most recruiting trials in San Francisco compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in San Francisco?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in San Francisco?
The most common conditions under active study in San Francisco include Breast Cancer (28), Prostate Cancer (27), Heart Failure (18), HIV (16), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in San Francisco?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in San Francisco on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in San Francisco?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in San Francisco?
Recruiting research sites in San Francisco include University of California, San Francisco, University of California San Francisco, Power Life Sciences, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in San Francisco right now?
The largest active categories in San Francisco are Cancer & tumors (396), Neurology & pain (83), Cardiovascular (82). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.