Portable MRI for Pediatric Hypoxic Ischemic Brain Injury

Part of paid clinical trials in Kansas City, Missouri.

Sponsor
Children's Mercy Hospital Kansas City
Study ID
NCT07577336
Status
Recruiting
Apply to this trial

Conditions

  • Acute Brain Injury
  • Brain Injuries
  • Hypoxia, Brain
  • Ischemia, Brain
  • Stroke
  • Trauma, Brain

Eligibility Criteria

Sex
ALL
Age
N/A - 17 Years
Healthy Volunteers
Not accepted

Interventions

  • Portable MRI — DEVICE
    Enrolled subjects will undergo a portable, ultralow-field MRI (pMRI) at the bedside in the ICU location within +/- 24 hours of a clinically obtained, conventional MRI and/or head CT
  • Scavenged Sample Collection — OTHER
    Remaining blood or cerebrospinal fluid samples from clinical testing will be scavenged at timepoints correlating to the radiology imaging.

Study Details

This study will evaluate the sensitivity and specificity of low field portable MRI (pMRI) for detection of hypoxic ischemic brain injuries in pediatric patients compared to clinically obtained neuroimaging to define pediatric diagnostic limitations and to determine the diagnostic capabilities of this neuroimaging modality following optimization of image acquisition. The results of this study will help determine optimal clinical implementation opportunities in pediatric patients.

Key Dates

First listed
May 11, 2026
Start date
Jul 6, 2026
Status verified
Jul 2026
Primary completion
Dec 31, 2027
Completion
Dec 31, 2027

Study Design

Enrollment
200 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC

Arms

  • Experimental: Portable MRI Arm
    All subjects enrolled with be assigned to Arm 1

Primary Outcome Measure

Determine the sensitivity and specificity of pMRI for detection of acute pediatric focal ischemic brain injuries. [ Time Frame: During intensive care admittance, an average of 1 month ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Children's Mercy Hospital and ClinicsKansas CityMissouri64108
Maura Sien, RT(R), CCRC
[email protected]
Jessica Wallisch, MD
[email protected]

Find similar trials in Kansas City, MO

By condition
Stroke
By specialty
NeurologyBrain disorders
By research site
Children's Mercy Hospital and Clinics· Kansas City, MO

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