Insomnia and Post-Dental Surgery Pain: A Prospective Study

Conditions

• Dental
• Dental Extraction
• Insomnia

Eligibility Criteria

Sex

ALL

Age

18 Years - N/A

Healthy Volunteers

Not accepted

Study Details

The purpose of this prospective observational study is to evaluate the relationship between preoperative sleep disturbances-specifically insomnia-and postoperative pain intensity following oral surgical procedures. Recent scientific literature highlights a bidirectional relationship between sleep disorders and pain in dentistry, suggesting that disturbed sleep may actively exacerbate subsequent pain perception. Although postoperative pain, swelling, and masticatory difficulties are common after dental extractions, clinical data investigating the direct impact of preoperative sleep quality on these surgical outcomes remain scarce. This study will enroll adult patients undergoing routine dental extractions and allocate them into two cohorts based on their baseline sleep quality: patients without preoperative sleep disturbances and patients with preoperative sleep disturbances. Pain levels and sleep parameters will be assessed using validated questionnaires before the surgery and at a 7-day follow-up. The primary objective is to determine whether the presence of preoperative insomnia leads to a significant increase in perceived postoperative surgical pain.

Key Dates

First listed

Jul 17, 2026

Start date

Sep 1, 2026

Status verified

Sep 2026

Primary completion

Nov 30, 2026

Completion

Jun 30, 2027

Study Design

Enrollment

90 participants (estimated)

Arms

• Arm: Patients without preoperative sleep disturbance
  Adult patients undergoing dental extractions who do not exhibit preoperative sleep disturbances. Target Number: 45 participants.
• Arm: Patients with preoperative sleep disturbance
  Adult patients undergoing dental extractions who exhibit preoperative sleep disturbances. Target number: 45 participants.

Primary Outcome Measure

Change in Perceived Pain Intensity (VAS) [ Time Frame: Baseline (pre-surgery) and 7 days post-dental extraction. ]

Central Contacts

• Prof. Patrizia Gallenzi
  +39 063015 5413
  [email protected]

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