Insomnia Clinical Trials

Recruiting insomnia studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat insomnia. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting insomnia studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting insomnia trials

Within

Study of Bedroom Environment Sleep Intervention at Home for Older Adults Living Alone With Memory Concerns

for Subjective Cognitive Decline (SCD)

Sponsor: Johns Hopkins University

Sex: All·Age: 65+

Code: NCT07440498

Efficacy of Digital CBT-I Utilizing Embodied Artificial Intelligence Agent in Virtual Reality

for Insomnia

Sponsor: Chinese University of Hong Kong

Sex: All·Age: 18 - 65

Code: NCT07699042

Deaf CBT-TS to Reduce Suicide Risk

for Depression - Major Depressive Disorder

1 site in Rochester

Sponsor: University of Rochester

Sex: All·Age: 18+

Code: NCT07279363

Targeting Insomnia to Prevent Depression in the Menopause Transition

for Insomnia

Sponsor: SRI International

Sex: Female·Age: 40+

Code: NCT07443644

Evaluating the Impact of Digital Behavioral Interventions to Address Insomnia and Depression in Breast Cancer Survivors Using an Adaptive Design

for Insomnia

1 site in Charlottesville

Sponsor: University of Virginia

Sex: Female·Age: 18+

Code: NCT07721064

Racism-related Stress and Objective Short-sleep as Moderators of Treatment Effect in Cognitive Behavioral Therapy for Insomnia

for Insomnia

Sponsor: Johns Hopkins University

Sex: All·Age: 18 - 65

Code: NCT07445529

Suvorexant 3 - PE-PC

for PTSD - Post Traumatic Stress Disorder

1 site in San Francisco

Sponsor: Northern California Institute of Research and Education

Sex: All·Age: 18 - 75

Code: NCT07686731·Phase 4

Daridorexant for People With Insomnia and Alcohol Use Disorder Study

for Alcohol Use Disorder

1 site in Spokane

Sponsor: Sterling McPherson

Sex: All·Age: 18+

Code: NCT07701928·Phase 2

Psychological Intervention on Cold Executive Function and Academic Performance in University Women With Insomnia

for Insomnia

Sponsor: Universidad Autonoma de Baja California

Sex: Female·Age: 18 - 25

Code: NCT07529652

Effects of Lemborexant on Motor-sleep Comorbidity in Parkinson's Disease

for Parkinson's Disease

Sponsor: YangPan

Sex: All·Age: 50+

Code: NCT07384429·Phase 4

Wearable Voice-Guided BBTi for Comorbid Insomnia and Sleep Apnea (COMISA)

for Comorbid Insomnia and Sleep Apnea

Sponsor: National Sun Yat-sen University

Sex: All·Age: 20 - 80

Code: NCT07521319

Efficacy of CBT-I With Adjuvant Melatonin in Older Adults Chronic Insomnia

for Insomnia

Sponsor: The University of Hong Kong

Sex: All·Age: 60+

Code: NCT07695246

4-7-8 Breathing for Fatigue and Sleep Management in Hemodialysis

for Chronic Kidney Diseases

Sponsor: Izmir Kavram Vocational School

Sex: All·Age: 18 - 85

Code: NCT07700693

A Study of Dimdazenil in Patients With Parkinson's Disease and Insomnia

for Insomnia

Sponsor: Second Affiliated Hospital of Soochow University

Sex: All·Age: 18+

Code: NCT07714772

Clinical Trial for Acupuncture in Adolescents With Psychological Distress and Insomnia

for Psychological Distress

Sponsor: The University of Hong Kong

Sex: All·Age: 15 - 22

Code: NCT06638450

Auditory Stimulation for Insomnia and Depression

for Depression - Major Depressive Disorder

1 site in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 20 - 50

Code: NCT07553364

NeuroFinance Human Stress Trial During Financial and Informational Volatility

for Psychological Stress

1 site in New York

Sponsor: Truway Health, Inc.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07622589

A Theory-based Sleep Hygiene Education for Insomnia Disorder

for Insomnia

Sponsor: The Hong Kong Polytechnic University

Sex: All·Age: 18 - 65

Code: NCT07642479

SleepSMART for Veterans With Insomnia and Mild Cognitive Impairment

for Insomnia

1 site in San Diego

Sponsor: VA Office of Research and Development

Sex: All·Age: 60+

Code: NCT07397182

CBT-I in Physically Active Participants With Insomnia Complaints

for Insomnia

Sponsor: Federal University of Jatai

Sex: All·Age: 30 - 59

Code: NCT07607444

Digital Insomnia and Circadian Therapy for Reducing Depression Symptoms in College Students

for Eveningness

Sponsor: Chinese University of Hong Kong

Sex: All·Age: 18 - 24

Code: NCT07677930

Clinical Investigation to Observe the Long-term Safety and Efficacy of the Digital Medical Device 'BELL-001' in Patients Diagnosed With Insomnia

for Insomnia

Sponsor: BELL Therapeutics Inc.

Sex: All·Age: 19 - 75

Code: NCT07582809

Brief Behavioral Intervention for Insomnia Among Adults With Sleep Disturbances

for Sleep Disturbance

Sponsor: National Taiwan University Hospital

Sex: All·Age: 18+

Code: NCT07603687

Post-Concussion Sleep and Brain-heart Functions

for Insomnia

Sponsor: University of Ottawa

Sex: All·Age: 18+

Code: NCT07636408

Insomnia and Post-Dental Surgery Pain: A Prospective Study

for Dental

Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Sex: All·Age: 18+

Code: NCT07712432

Parent-Mediated Telehealth Intervention for Insomnia in Young Autistic Children

for Insomnia

3 sites incl. Atlanta

Sponsor: Emory University

Sex: All·Age: 3 - 7

Code: NCT07435740

Apply to this trial

The Effects of Orexin Antagonism on Fear Extinction in PTSD

for Insomnia

2 sites incl. San Francisco

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 75

Code: NCT06788522·Phase 4

Enhancing Diabetes Care by Treating Insomnia

for Diabetes Type 2

1 site in Zachary

Sponsor: Tulane University

Sex: All·Age: 40+

Code: NCT07062406

INSIGHT: Insomnia, Nightmares, and Sympathetic Hyperactivity Intervention

for Nightmare

2 sites incl. Bethesda

Sponsor: Uniformed Services University of the Health Sciences

Sex: All·Age: 18 - 62·Accepts healthy volunteers

Code: NCT07288593

Insomnia and Insulin Resistance

for Insomnia

Sponsor: University of Missouri-Columbia

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT07333586

THC Versus THC/CBD Versus Placebo to Improve Sleep Quality for Patients With Solid Organ Cancer and Insomnia

for Insomnia

1 site in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 25+

Code: NCT07565974·Phase 2

The Impact of Brief Behavioral Treatment for Insomnia Versus Brief Mindfulness Treatment on Cognition and Sleep Health in Adults (Age 50+) With HIV

for Insomnia

2 sites incl. Birmingham

Sponsor: University of Alabama, Tuscaloosa

Sex: All·Age: 50 - 99

Code: NCT07272863

Electroacupuncture for Insomnia in Patients With Chronic Sciatica Due to Lumbar Disc Herniation: a Randomized Controlled Trial

for Sciatica

Sponsor: Shanghai Yueyang Integrated Medicine Hospital

Sex: All·Age: 18 - 75

Code: NCT07576348

Effects of Accelerated rTMS on Sleep Architecture in Chronic Insomnia Disorder

for Insomnia

1 site in San Francisco

Sponsor: San Francisco Neurology and Sleep Center

Sex: All·Age: 18 - 85

Code: NCT07595185

A Theory-based Sleep Hygiene Education for Insomnia Patients

for Insomnia

Sponsor: The Hong Kong Polytechnic University

Sex: All·Age: 18 - 65

Code: NCT07559305

Effects of Aromatherapy on Sleep Quality in Hospitalized Elderly Female Patients With Insomnia

for Insomnia

Sponsor: The Second Hospital of Anhui Medical University

Sex: Female·Age: 60 - 100·Accepts healthy volunteers

Code: NCT07373132

Study of the Effect of Spa Therapy on Insomnia

for Insomnia

Sponsor: Clinique Beau Soleil

Sex: All·Age: 18 - 90

Code: NCT07473011

A SMART Approach to Evaluating the Benefits of Common Prescription and OTC Medications for Insomnia

for Insomnia

1 site in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 80

Code: NCT07542756·Phase 4

Apply to this trial

Effect of Acupuncture on Psychoneurological Symptom Cluster in Breast Cancer Survivors

for Psychoneurological Symptom Cluster(Pain, Insomnia, Anxiety, Fatigue, Depression, Subjective Cognitive Decline)

Sponsor: First Teaching Hospital of Tianjin University of Traditional Chinese Medicine

Sex: Female·Age: 18 - 75

Code: NCT07481903

Mindfulness for Informal Caregivers

for Mental Health

Sponsor: The University of Hong Kong

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07496138

COMPARATIVE EFFECTIVENESS OF EXERCISE, COGNITIVE BEHAVIOURAL THERAPY, AND THEIR COMBINATION FOR PEOPLE WITH CHRONIC MUSCULOSKELETAL PAIN AND POOR SLEEP: SLEEPFIT TRIAL

for Osteo Arthritis Knee and Hip

2 sites incl. San Antonio

Sponsor: University of Sydney

Sex: All·Age: 18+

Code: NCT07532070

Apply to this trial

Efficacy and Safety of Daridorexant in Patients With Major Depressive Disorder and Insomnia

for Insomnia

Sponsor: Institut d'Investigació Biomèdica de Bellvitge

Sex: All·Age: 18 - 99

Code: NCT07555743·Phase 4

Artificial Intelligence (AI)-Assisted Sleep Intervention for Insomnia in Older Adults With Subjective Cognitive Decline

for Insomnia

Sponsor: The Hong Kong Polytechnic University

Sex: All·Age: 60+

Code: NCT07588035

Piloting an Insomnia Treatment in Patients With Ulcerative Colitis

for Insomnia

1 site in Lebanon

Sponsor: Dartmouth-Hitchcock Medical Center

Sex: All·Age: 18+

Code: NCT07428629

Apply to this trial

Auricular Laser Acupuncture for Improving Sleep in Breast Cancer Patients

for Breast Cancer Females

Sponsor: CHING-RONG HUANG

Sex: Female·Age: 18 - 75

Code: NCT07547423

Mindfulness Meditation for Insomnia

for Sleep Initiation and Maintenance Disorders

1 site in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18+

Code: NCT06972303·Phase 1, Phase 2

Apply to this trial

Transcutaneous Auricular Vagus Nerve Stimulation for Insomnia in Survivors of Childhood Acute Lymphoblastic Leukemia

for Survivor of Childhood Cancer

1 site in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 20 - 50

Code: NCT07191119

Apply to this trial

Efficacy and Safety of APSTZD in the Treatment of Insomnia Disorder

for Insomnia

Sponsor: Apsen Farmaceutica S.A.

Sex: All·Age: 18 - 64

Code: NCT07420816·Phase 2

Sleep and Stroke Rehabilitation Study

for Stroke

Sponsor: Malin Eleonora av Kák Gustafsson, MD, PhD

Sex: All·Age: 18+

Code: NCT07579871

Apply to this trial

Ning Shen Dan Xiang Gao Fang for Heart-Kidney Disharmony Insomnia

for Insomnia

Sponsor: Shanghai 7th People's Hospital

Sex: All·Age: 18+

Code: NCT07504536·Phase 2

ASV Therapy for Insomnia

for Insomnia

1 site in Detroit

Sponsor: ResMed

Sex: All·Age: 18+

Code: NCT07011966

Apply to this trial

Deep Sleep in Older Adults

for Insomnia

1 site in New York

Sponsor: Proactive Life Inc

Sex: All·Age: 65+

Code: NCT07316153·Phase 2

Enhancing Operational Readiness With Digital Self-Managed Cognitive Behavioral Therapy for Insomnia (CBTI)

for Insomnia

Sponsor: Madigan Army Medical Center

Sex: All·Age: 18 - 55

Code: NCT07335276

Home-Based Auricular Transcutaneous Vagus Nerve Stimulation (tVNS) for Sleep Quality and Psycho-Academic Outcomes in Health Sciences Students

for Sleep Disturbances

Sponsor: University of Malaga

Sex: All·Age: 18 - 35

Code: NCT07371715

Understanding the Role of the Locus Coeruleus in Insomnia

for Insomnia

Sponsor: Woolcock Institute of Medical Research

Sex: All·Age: 30 - 65

Code: NCT07392177·Phase 2

Healthy Behaviors for Insomnia Prevention in People With HIV and Ongoing Pain

for Chronic Pain

1 site in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 25 - 65

Code: NCT07270406

Apply to this trial

Comparing Digital Therapy, Trazodone, and Daridorexant for Menopause-Related Insomnia Symptoms

for Menopausal Women

5 sites incl. Boston

Sponsor: Brigham and Women's Hospital

Sex: Female·Age: 40 - 62

Code: NCT07136415·Phase 4

Apply to this trial

Impact of Daridorexant on Sleep, Daytime Alertness, and Smoking

for Smoking

1 site in Portland

Sponsor: Legacy Health System

Sex: All·Age: 18 - 55

Code: NCT07328594·Phase 4

CF Wellness Program

for Cystic Fibrosis (CF)

3 sites incl. Denver

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT07071324

Apply to this trial

SleepFix for Youth: Digital Behavioural Therapy for Insomnia With E-Psychologist Support

for Insomnia

Sponsor: Woolcock Institute of Medical Research

Sex: All·Age: 16 - 24

Code: NCT07405775

Insomnia clinical trials — common questions

Are insomnia clinical trials free to join?

Yes. Participating in a insomnia clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a insomnia clinical trial?

Each insomnia study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a insomnia trial near me?

Use the location controls above. We'll show recruiting insomnia trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many insomnia trials are recruiting right now?

We're currently tracking roughly 81 recruiting insomnia trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Insomnia trials by city

Boston, MA San Francisco, CA Denver, CO Los Angeles, CA Ann Arbor, MI Chicago, IL Detroit, MI Indianapolis, IN Palo Alto, CA San Diego, CA Tampa, FL Aurora, CO

Related specialties

Mental health Sleep medicine