Sleep medicine Clinical Trials

Recruiting sleep medicine studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat sleep medicine. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting sleep medicine studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting sleep medicine trials

Within

PAP Systems External Clinical Studies (ECS)

for Obstructive Sleep Apnea

Sponsor: ResMed

Sex: All·Age: 18 - 130·Accepts healthy volunteers

Code: NCT06562205

Behavioral Optimization to Overcome Obstructive Sleep Apnea Treatment Barriers

for Sleep Apnea

2 sites incl. West Los Angeles

Sponsor: VA Office of Research and Development

Sex: All·Age: 50+

Code: NCT07207473

Study of Bedroom Environment Sleep Intervention at Home for Older Adults Living Alone With Memory Concerns

for Subjective Cognitive Decline (SCD)

Sponsor: Johns Hopkins University

Sex: All·Age: 65+

Code: NCT07440498

Efficacy of Digital CBT-I Utilizing Embodied Artificial Intelligence Agent in Virtual Reality

for Insomnia

Sponsor: Chinese University of Hong Kong

Sex: All·Age: 18 - 65

Code: NCT07699042

Enhancing PAP Adherence Among Spanish-speaking Hispanic Adults With OSA

for Obstructive Sleep Apnea

4 sites incl. Fontana

Sponsor: Geisinger Clinic

Sex: All·Age: 18+

Code: NCT05618444

Deaf CBT-TS to Reduce Suicide Risk

for Depression - Major Depressive Disorder

1 site in Rochester

Sponsor: University of Rochester

Sex: All·Age: 18+

Code: NCT07279363

Targeting Insomnia to Prevent Depression in the Menopause Transition

for Insomnia

Sponsor: SRI International

Sex: Female·Age: 40+

Code: NCT07443644

A Study Of Synthetic THC And Sleep

for Obstructive Sleep Apnea

1 site in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 21 - 70

Code: NCT07570953·Phase 2, Phase 3

Evaluating the Impact of Digital Behavioral Interventions to Address Insomnia and Depression in Breast Cancer Survivors Using an Adaptive Design

for Insomnia

1 site in Charlottesville

Sponsor: University of Virginia

Sex: Female·Age: 18+

Code: NCT07721064

Impact of Exogenous Ketones on Sleep Apnea

for Obstructive Sleep Apnea

1 site in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18 - 65

Code: NCT06687655·Phase 1, Phase 2

Racism-related Stress and Objective Short-sleep as Moderators of Treatment Effect in Cognitive Behavioral Therapy for Insomnia

for Insomnia

Sponsor: Johns Hopkins University

Sex: All·Age: 18 - 65

Code: NCT07445529

Suvorexant 3 - PE-PC

for PTSD - Post Traumatic Stress Disorder

1 site in San Francisco

Sponsor: Northern California Institute of Research and Education

Sex: All·Age: 18 - 75

Code: NCT07686731·Phase 4

Daridorexant for People With Insomnia and Alcohol Use Disorder Study

for Alcohol Use Disorder

1 site in Spokane

Sponsor: Sterling McPherson

Sex: All·Age: 18+

Code: NCT07701928·Phase 2

Cognitive Function and Quality of Life in Obstructive Sleep Apnea

for Obstructive Sleep Apnea

Sponsor: Assiut University

Sex: All·Age: 18+

Code: NCT07678918

Psychological Intervention on Cold Executive Function and Academic Performance in University Women With Insomnia

for Insomnia

Sponsor: Universidad Autonoma de Baja California

Sex: Female·Age: 18 - 25

Code: NCT07529652

Effects of Lemborexant on Motor-sleep Comorbidity in Parkinson's Disease

for Parkinson's Disease

Sponsor: YangPan

Sex: All·Age: 50+

Code: NCT07384429·Phase 4

Myofunctional Therapy for Obstructive Sleep Apnea

for Obstructive Sleep Apnea

1 site in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 65

Code: NCT07301125

Apply to this trial

Wearable Voice-Guided BBTi for Comorbid Insomnia and Sleep Apnea (COMISA)

for Comorbid Insomnia and Sleep Apnea

Sponsor: National Sun Yat-sen University

Sex: All·Age: 20 - 80

Code: NCT07521319

Efficacy of CBT-I With Adjuvant Melatonin in Older Adults Chronic Insomnia

for Insomnia

Sponsor: The University of Hong Kong

Sex: All·Age: 60+

Code: NCT07695246

4-7-8 Breathing for Fatigue and Sleep Management in Hemodialysis

for Chronic Kidney Diseases

Sponsor: Izmir Kavram Vocational School

Sex: All·Age: 18 - 85

Code: NCT07700693

A Study of Dimdazenil in Patients With Parkinson's Disease and Insomnia

for Insomnia

Sponsor: Second Affiliated Hospital of Soochow University

Sex: All·Age: 18+

Code: NCT07714772

Association Between Metabolic Associated Fatty Liver Disease and Obstructive Sleep Apnea

for Obstructive Sleep Apnea

Sponsor: Assiut University

Sex: All·Age: 18 - 60

Code: NCT07716995

Clinical Trial for Acupuncture in Adolescents With Psychological Distress and Insomnia

for Psychological Distress

Sponsor: The University of Hong Kong

Sex: All·Age: 15 - 22

Code: NCT06638450

Auditory Stimulation for Insomnia and Depression

for Depression - Major Depressive Disorder

1 site in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 20 - 50

Code: NCT07553364

Transcutaneous Electrical Stimulation in Patients With Obstructive Sleep Apnoea

for Obstructive Sleep Apnea

Sponsor: Zeus Sleep Ltd

Sex: All·Age: 18+

Code: NCT07343362

NeuroFinance Human Stress Trial During Financial and Informational Volatility

for Psychological Stress

1 site in New York

Sponsor: Truway Health, Inc.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07622589

A Theory-based Sleep Hygiene Education for Insomnia Disorder

for Insomnia

Sponsor: The Hong Kong Polytechnic University

Sex: All·Age: 18 - 65

Code: NCT07642479

KPAP Adherence Crossover Study

for Obstructive Sleep Apnea

1 site in Murfreesboro

Sponsor: SleepRes Inc.

Sex: All·Age: 20 - 80

Code: NCT06413134

Post-Operative Steroids After Sleep Surgery

for Obstructive Sleep Apnea

1 site in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT06818981·Phase 2

SleepSMART for Veterans With Insomnia and Mild Cognitive Impairment

for Insomnia

1 site in San Diego

Sponsor: VA Office of Research and Development

Sex: All·Age: 60+

Code: NCT07397182

KPAP vs EPR for Efficacy

for Obstructive Sleep Apnea

Sponsor: SleepRes Inc.

Sex: All·Age: 20 - 80

Code: NCT07530523

CBT-I in Physically Active Participants With Insomnia Complaints

for Insomnia

Sponsor: Federal University of Jatai

Sex: All·Age: 30 - 59

Code: NCT07607444

Effects of a Pacifier on Obstructive Sleep Apnea and Its Repercussions in Infants With Down Syndrome

for Obstructive Sleep Apnea

Sponsor: Hospices Civils de Lyon

Sex: All·Age: 23 Days - 38 Days

Code: NCT07658053

Digital Insomnia and Circadian Therapy for Reducing Depression Symptoms in College Students

for Eveningness

Sponsor: Chinese University of Hong Kong

Sex: All·Age: 18 - 24

Code: NCT07677930

Bi-lateral HGN Therapy in Real-World Patients -Post Approval Research Investigation

for Obstructive Sleep Apnea

2 sites incl. Miami

Sponsor: Nyxoah Inc.

Sex: All·Age: 22+

Code: NCT07331285

Apply to this trial

Clinical Investigation to Observe the Long-term Safety and Efficacy of the Digital Medical Device 'BELL-001' in Patients Diagnosed With Insomnia

for Insomnia

Sponsor: BELL Therapeutics Inc.

Sex: All·Age: 19 - 75

Code: NCT07582809

Brief Behavioral Intervention for Insomnia Among Adults With Sleep Disturbances

for Sleep Disturbance

Sponsor: National Taiwan University Hospital

Sex: All·Age: 18+

Code: NCT07603687

Post-Concussion Sleep and Brain-heart Functions

for Insomnia

Sponsor: University of Ottawa

Sex: All·Age: 18+

Code: NCT07636408

Insomnia and Post-Dental Surgery Pain: A Prospective Study

for Dental

Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Sex: All·Age: 18+

Code: NCT07712432

Prospective Evaluation of New Metrics to Assess Cardiovascular Remodeling in Obstructive Sleep Apnea

for Obstructive Sleep Apnea

Sponsor: University Hospital, Antwerp

Sex: All·Age: 18+

Code: NCT07427589

Apply to this trial

Parent-Mediated Telehealth Intervention for Insomnia in Young Autistic Children

for Insomnia

3 sites incl. Atlanta

Sponsor: Emory University

Sex: All·Age: 3 - 7

Code: NCT07435740

Apply to this trial

The Effects of Orexin Antagonism on Fear Extinction in PTSD

for Insomnia

2 sites incl. San Francisco

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 75

Code: NCT06788522·Phase 4

Enhancing Diabetes Care by Treating Insomnia

for Diabetes Type 2

1 site in Zachary

Sponsor: Tulane University

Sex: All·Age: 40+

Code: NCT07062406

INSIGHT: Insomnia, Nightmares, and Sympathetic Hyperactivity Intervention

for Nightmare

2 sites incl. Bethesda

Sponsor: Uniformed Services University of the Health Sciences

Sex: All·Age: 18 - 62·Accepts healthy volunteers

Code: NCT07288593

Insomnia and Insulin Resistance

for Insomnia

Sponsor: University of Missouri-Columbia

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT07333586

KPAP vs EPR for Comfort

for Obstructive Sleep Apnea

Sponsor: SleepRes Inc.

Sex: All·Age: 20 - 80

Code: NCT07530510

THC Versus THC/CBD Versus Placebo to Improve Sleep Quality for Patients With Solid Organ Cancer and Insomnia

for Insomnia

1 site in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 25+

Code: NCT07565974·Phase 2

Combination Upper-Airway Electrical and Pharmacological Stimulation for Obstructive Sleep Apnea

for Obstructive Sleep Apnea

1 site in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 79

Code: NCT07577661·Phase 1, Phase 2

The Impact of Brief Behavioral Treatment for Insomnia Versus Brief Mindfulness Treatment on Cognition and Sleep Health in Adults (Age 50+) With HIV

for Insomnia

2 sites incl. Birmingham

Sponsor: University of Alabama, Tuscaloosa

Sex: All·Age: 50 - 99

Code: NCT07272863

Orofacial Myofunctional Therapy and Positive Airway Pressure-CPAP Trial for Mild-to-Moderate Obstructive Sleep Apnea

for Obstructive Sleep Apnea

Sponsor: Saint-Joseph University

Sex: All·Age: 18+

Code: NCT07539870

Electroacupuncture for Insomnia in Patients With Chronic Sciatica Due to Lumbar Disc Herniation: a Randomized Controlled Trial

for Sciatica

Sponsor: Shanghai Yueyang Integrated Medicine Hospital

Sex: All·Age: 18 - 75

Code: NCT07576348

Effects of Accelerated rTMS on Sleep Architecture in Chronic Insomnia Disorder

for Insomnia

1 site in San Francisco

Sponsor: San Francisco Neurology and Sleep Center

Sex: All·Age: 18 - 85

Code: NCT07595185

Continuous Positive Airway Pressure, Arousability and Links to Mechanisms in Obstructive Sleep Apnea

for Sleep Apnea

1 site in North Haven

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT07332442·Phase 3

Apply to this trial

Start CPAP Therapy in Obstructive Sleep Apnea Patients After Atrial Fibrillation Ablation

for Obstructive Sleep Apnea

Sponsor: Beijing Anzhen Hospital

Sex: All·Age: 18 - 75

Code: NCT07444372

Apply to this trial

A Theory-based Sleep Hygiene Education for Insomnia Patients

for Insomnia

Sponsor: The Hong Kong Polytechnic University

Sex: All·Age: 18 - 65

Code: NCT07559305

Effects of Aromatherapy on Sleep Quality in Hospitalized Elderly Female Patients With Insomnia

for Insomnia

Sponsor: The Second Hospital of Anhui Medical University

Sex: Female·Age: 60 - 100·Accepts healthy volunteers

Code: NCT07373132

Study of the Effect of Spa Therapy on Insomnia

for Insomnia

Sponsor: Clinique Beau Soleil

Sex: All·Age: 18 - 90

Code: NCT07473011

A SMART Approach to Evaluating the Benefits of Common Prescription and OTC Medications for Insomnia

for Insomnia

1 site in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 80

Code: NCT07542756·Phase 4

Apply to this trial

Residual Sleepiness and Accident Risk in Treated Obstructive Sleep Apnea

for Obstructive Sleep Apnea

Sponsor: Hospices Civils de Lyon

Sex: All·Age: 18+

Code: NCT07545421

Effect of Acupuncture on Psychoneurological Symptom Cluster in Breast Cancer Survivors

for Psychoneurological Symptom Cluster(Pain, Insomnia, Anxiety, Fatigue, Depression, Subjective Cognitive Decline)

Sponsor: First Teaching Hospital of Tianjin University of Traditional Chinese Medicine

Sex: Female·Age: 18 - 75

Code: NCT07481903

Sleep medicine clinical trials — common questions

Are sleep medicine clinical trials free to join?

Yes. Participating in a sleep medicine clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a sleep medicine clinical trial?

Each sleep medicine study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a sleep medicine trial near me?

Use the location controls above. We'll show recruiting sleep medicine trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many sleep medicine trials are recruiting right now?

We're currently tracking roughly 177 recruiting sleep medicine trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Sleep medicine trials by city

Boston, MA Detroit, MI Ann Arbor, MI San Francisco, CA Chicago, IL La Jolla, CA Los Angeles, CA Miami, FL Aurora, CO Denver, CO Indianapolis, IN San Diego, CA

Conditions in this area

Insomnia Obstructive sleep apnea