A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight

Part of paid clinical trials in Fairhope, Alabama.

Sponsor
AstraZeneca
Study ID
NCT07784270
Phase
PHASE3
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • AZD6234 — DRUG
    IMP injected subcutaneously, once a week. Unit dose strength as per CSP.
  • Placebo — DRUG
    Placebo matching IMP dose injected subcutaneously, once a week.

Study Details

The study will evaluate how well AZD6234 works and how safe it is in adults with excess weight or obesity. Efficacy of AZD6234 will be compared to placebo in percent body weight change from baseline at 68 weeks of treatment

Key Dates

First listed
Aug 25, 2026
Start date
Aug 20, 2026
Status verified
Sep 2026
Primary completion
Aug 8, 2028
Completion
Aug 8, 2028

Study Design

Enrollment
1,500 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: AZD6234 Dose 1
    AZD6234 Dose 1
  • Experimental: AZD6234 Dose 2
    AZD6234 Dose 2
  • Placebo Comparator: Placebo
    Matching placebo

Primary Outcome Measure

Percent change in body weight from baseline at 68 weeks of treatment. [ Time Frame: 68 weeks ]

Central Contacts

Locations (54)

FacilityCityStateZIPSite coordinators
Research SiteFairhopeAlabama36532-
Research SiteHuntsvilleAlabama35801-
Research SiteMobileAlabama36608-
Research SiteMesaArizona85213-
Research SitePhoenixArizona85044-
Research SiteTucsonArizona85715-
Research SiteLittle RockArkansas72205-
Research SiteBakersfieldCalifornia93309-
Research SiteGardenaCalifornia90247-
Research SiteLincolnCalifornia95648-
Research SiteTorranceCalifornia90503-
Research SiteWalnut CreekCalifornia94598-
Research SiteCoral GablesFlorida33134-
Research SiteFleming IslandFlorida32003-
Research SiteFort LauderdaleFlorida33316-
Research SiteOcoeeFlorida34761-
Research SiteWoodstockGeorgia30189-
Research SiteChicagoIllinois60640-
Research SiteMelrose ParkIllinois60160-
Research SiteLenexaKansas66219-
Research SiteNewtonKansas67114-
Research SiteMonroeLouisiana71201-
Research SiteBeltsvilleMaryland20705-
Research SiteLanhamMaryland20706-
Research SiteOxon HillMaryland20745-
Research SiteRockvilleMaryland20852-
Research SiteNorth DartmouthMassachusetts02747-
Research SiteFarmington HillsMichigan48336-
Research SiteFayetteMississippi39069-
Research SiteKansas CityMissouri64111-
Research SiteKansas CityMissouri64114-
Research SiteSt LouisMissouri63141-
Research SiteOmahaNebraska68114-
Research SiteOmahaNebraska68144-
Research SiteEatontownNew Jersey07724-
Research SiteSomersetNew Jersey08873-
Research SiteWarren TownshipNew Jersey07059-
Research SiteGreensboroNorth Carolina27408-
Research SiteMonroeNorth Carolina28112-
Research SiteKentOhio44240-
Research SiteScottdalePennsylvania15683-
Research SiteFranklinTennessee37067-
Research SiteJacksonTennessee38305-
Research SiteKnoxvilleTennessee37938-
Research SiteDeSotoTexas75115-
Research SiteEl PasoTexas79935-
Research SiteHoustonTexas77099-
Research SiteMidlandTexas79707-
Research SitePasadenaTexas77504-
Research SiteSan AntonioTexas78207-
Research SiteSan AntonioTexas78215-
Research SiteSan AntonioTexas78251-
Research SiteManassasVirginia20110-
Research SiteNorfolkVirginia23504-

Find similar trials in Fairhope, AL

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By condition
Type 2 diabetes
By specialty
EndocrinologyMetabolic healthWeight loss

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