An Open-label Extension Study of the Long-Term Safety of Vonaprument (ANX007) in Participants With Dry Age-Related Macular Degeneration (AMD) With Geographic Atrophy (GA)
Part of paid clinical trials in Sarasota, Florida.
- Sponsor
- Annexon, Inc.
- Study ID
- NCT07807969
- Phase
- PHASE3
- Status
- Not Yet Recruiting
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Conditions
Eligibility Criteria
- Sex
- ALL
- Age
- 50 Years - N/A
- Healthy Volunteers
- Not accepted
Interventions
- Vonaprument — DRUGForm: solution for injection; Route of Administration: IVT injection
Study Details
The primary purpose of the study is to assess the long term safety of intravitreal (IVT) injections of vonaprument.
Key Dates
- First listed
- Sep 8, 2026
- Start date
- Sep 30, 2026
- Status verified
- Sep 2026
- Primary completion
- Jul 31, 2029
- Completion
- Jul 31, 2029
Study Design
- Enrollment
- 605 participants (estimated)
- Allocation
- NA
- Intervention model
- SINGLE_GROUP
- Primary purpose
- TREATMENT
Arms
- Experimental: VonaprumentParticipants will receive vonaprument IVT injections every month for 24 months.
Primary Outcome Measure
Number of Participants with Treatment Emergent Adverse Events [ Time Frame: Through Month 24 ]
Central Contacts
- Study Coordinator650-822-5500
Locations (7)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| Retina Group of Florida | Sarasota | Florida | 34233 | - |
| Retina Vitreous Associates of Florida | St. Petersburg | Florida | 33711 | - |
| Cumberland Valley Retina Consultants | Hagerstown | Maryland | 21740 | - |
| Mid Atlantic Retina Specialists | Hagerstown | Maryland | 21740 | - |
| Retina Research Institute at New England Retina Consultants | Springfield | Massachusetts | 01107 | - |
| Asheville Eye Associates - Retina Division | Asheville | North Carolina | 28803 | - |
| Verum Research, LLC | Eugene | Oregon | 97401 | - |
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