Phase II Elderly/Frail Pts With Newly Diagnosed or Recurrent Malignant Glioma Tx Treated With Cesium-131 GammaTile®

Part of paid clinical trials in Orange, California.

Sponsor
University of California, Irvine
Study ID
NCT07821112
Phase
PHASE2
Status
Not Yet Recruiting

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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • GammaTile® — DEVICE
    GammaTile is a bioabsorbable collagen tile embedded with cesium-131 radioactive seeds.

Study Details

This is a phase 2, open-label clinical trial determining feasibility, safety, and tolerability of GammaTile® in elderly or frail subjects with newly diagnosed or recurrent malignant gliomas.

Key Dates

First listed
Sep 15, 2026
Start date
Oct 31, 2026
Status verified
Sep 2026
Primary completion
Oct 31, 2027
Completion
Oct 31, 2029

Study Design

Enrollment
20 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Newly Diagnosed Elderly or Frail Glioblastoma
    GammaTile®
  • Experimental: Recurrent Elderly or Frail Glioblastoma
    GammaTile®
  • Experimental: Newly Diagnosed Frail (Non-GBM) Malignant Glioma
    GammaTile®
  • Experimental: Recurrent Frail (Non-GBM) Malignant Glioma
    GammaTile®

Primary Outcome Measure

Percentage of Participants who were able to receive the GammaTile Implant [ Time Frame: 28 days ]

Central Contacts

  • Chao Family Comprehensive Cancer Center University of California, Irvine
    1-877-827-8839
    [email protected]
  • University of California Irvine Medical

Locations (1)

FacilityCityStateZIPSite coordinators
Chao Family Comprehensive Cancer Center, University of California, IrvineOrangeCalifornia92868
Carlen Yuen, MD
[email protected]
877-827-8839

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Chao Family Comprehensive Cancer Center, University of California, Irvine· Orange, CA

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