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for Brain Cancer
1 location in Orange
Sponsor: University of California, Irvine
Sex: All·Age: 18+
Code: NCT07827001·Recruiting·Listed Sep 18, 2026
Paid Clinical Trials in Orange, CA
As of September 2026, 517 paid clinical trials are recruiting in Orange, California. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Orange offers studies at sites including Children's Hospital of Orange County for conditions such as Breast Cancer, Ovarian Cancer, Acute Myeloid Leukemia, Major Depressive Disorder. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Orange
Trials by drug in Orange
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Newly added in Orange
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
Nerve Block for Severe Abdominal Pain in the Emergency Department
for Erector Spinae Plane Block
1 location in Orange
Sponsor: University of California, Irvine
Sex: All·Age: 18+
Code: NCT07826936·EARLY_Phase 1·Recruiting·Listed Sep 17, 2026
Ph II Intraperitoneal Paclitaxel + System Therapy in GI Ca w/Peritoneal Carcinomatosis (STOPGAP-B)
for Esophageal Carcinoma
1 location in Orange
Sponsor: University of California, Irvine
Sex: All·Age: 18+
Code: NCT07795749·Phase 2·Recruiting·Listed Aug 31, 2026
Study of AZD0120 in Newly Diagnosed Multiple Myeloma Ineligible for ASCT
for Newly Diagnosed Multiple Myeloma
Sites in Orange, Santa Monica +42 more locations
Sponsor: AstraZeneca
Sex: All·Age: 18+
Code: NCT07764978·Phase 3·Recruiting·Listed Aug 14, 2026
478 clinical trials
Get a weekly email when new trials open in Orange, CA.
A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)
for Major Depressive Disorder
Sites in Orange, Santa Monica +28 more locations
Sponsor: Definium Therapeutics US, Inc.
Sex: All·Age: 18 - 74
Code: NCT07592689·Phase 3·Recruiting·Listed May 2026
A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD)
for Major Depressive Episode (MDE)
Sites in Orange, Chino +23 more locations
Sponsor: Tonix Pharmaceuticals, Inc.
Sex: All·Age: 18+
Code: NCT07621237·Phase 2·Recruiting·Listed Jun 2026
Multicenter Study to Assess the Efficacy and Safety of LB-102 in the Treatment of Adult Patients With BP1MDE.
for Bipolar I Disorder
Sites in Orange, Garden Grove +24 more locations
Sponsor: LB Pharmaceuticals Inc.
Sex: All·Age: 18 - 65
Code: NCT07494305·Phase 2·Recruiting·Listed Mar 2026
A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
for Solid Tumors
Drug: INCB161734
Sites in Orange, Fullerton +67 more locations
Sponsor: Incyte Corporation
Sex: All·Age: 18+
Code: NCT07522073·Phase 3·Recruiting·Listed Apr 2026
An Evaluation of the Safety and Efficacy of TSND-201 for the Treatment of PTSD (EMPOWER-1)
for Post Traumatic Stress Disorder
Drug: TSND-201
Sites in Orange, Montclair +35 more locations
Sponsor: Transcend Therapeutics
Sex: All·Age: 18+
Code: NCT07456696·Phase 3·Recruiting·Listed Mar 2026
A Study of Brenipatide in Adult Participants With Major Depressive Disorder
for Depressive Disorder, Major
Drug: Brenipatide
Sites in Orange, Moorpark +30 more locations
Sponsor: Eli Lilly and Company
Sex: All·Age: 18 - 75
Code: NCT07412756·Phase 3·Recruiting·Listed Feb 2026
A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer
for Pancreatic Cancer
Sites in Orange, Fullerton +47 more locations
Sponsor: Astellas Pharma Global Development, Inc.
Sex: All·Age: 18+
Code: NCT07409272·Phase 3·Recruiting·Listed Feb 2026
A Trial to Investigate Safety, Exposure, and Efficacy of HU6 Compared With Placebo in Adult Participants With Metabolic Dysfunction-associated Steatohepatitis (MASH)
for MASH - Metabolic Dysfunction-Associated Steatohepatitis
Sites in Orange, Garden Grove +29 more locations
Sponsor: Rivus Pharmaceuticals, Inc.
Sex: All·Age: 30+
Code: NCT07491458·Phase 2·Recruiting·Listed Mar 2026
A Study of a Thyroid Hormone Receptor Beta Isoform (THRβ) Agonist and an Semicarbazide Sensitive Amine Oxidase (SSAO) Inhibitor, Alone and in Combination, in Adults With Presumed Metabolic Dysfunction-associated Steatohepatitis (MASH)
for Metabolic Dysfunction-associated Steatohepatitis
Sites in Orange, Fountain Valley +61 more locations
Sponsor: Eccogene
Sex: All·Age: 18 - 75
Code: NCT07288138·Phase 2·Recruiting·Listed Dec 2025
Parasternal Extravascular ICD System Pivotal Clinical Investigation (ALARION EV) Study
for Ventricular Arrythmia
Sites in Orange, Santa Monica +25 more locations
Sponsor: AtaCor Medical, Inc.
Sex: All·Age: 18+
Code: NCT07324031·Recruiting·Listed Jan 2026
A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)
for Metabolic Dysfunction-Associated Steatotic Liver Disease
Sites in Orange, Fountain Valley +140 more locations
Sponsor: Eli Lilly and Company
Sex: All·Age: 18+
Code: NCT07165028·Phase 3·Recruiting·Listed Sep 2025
A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer
for Untreated, Unresectable, or Metastatic Colorectal Cancer
Drug: Bevacizumab
Sites in Orange, Los Angeles +42 more locations
Sponsor: Bristol-Myers Squibb
Sex: All·Age: 18+
Code: NCT07221357·Phase 2, Phase 3·Recruiting·Listed Oct 2025
A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Nivolumab in Combination With Chemotherapy in Participants With Previously Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (ROSETTA Gastric-204)
for Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma
Drug: Nivolumab
Sites in Orange, Los Angeles +32 more locations
Sponsor: Bristol-Myers Squibb
Sex: All·Age: 18+
Code: NCT07221149·Phase 2, Phase 3·Recruiting·Listed Oct 2025
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
for Diabetes Mellitus, Type 2
Drug: Empagliflozin
Sites in Orange, Long Beach +200 more locations
Sponsor: Boehringer Ingelheim
Sex: All·Age: 18+
Code: NCT07064473·Phase 3·Recruiting·Listed Jul 2025
A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract
for Carcinoma, Transitional Cell
Sites in Orange, Irvine +60 more locations
Sponsor: Eli Lilly and Company
Sex: All·Age: 18+
Code: NCT07218380·Phase 3·Recruiting·Listed Oct 2025
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
for Breast Neoplasms
Sites in Orange, Irvine +124 more locations
Sponsor: Eli Lilly and Company
Sex: All·Age: 18+
Code: NCT07174336·Phase 3·Recruiting·Listed Sep 2025
A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer
for Metastatic Castration-resistant Prostate Cancer
Sites in Orange, Fullerton +43 more locations
Sponsor: Amgen
Sex: Male·Age: 18+
Code: NCT07213674·Phase 3·Recruiting·Listed Oct 2025
Symbiotic-GI-13: A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body.
for Carcinoma, Hepatocellular
Drug: PF-08634404
Sites in Orange, Irvine +39 more locations
Sponsor: Pfizer
Sex: All·Age: 18+
Code: NCT07227012·Phase 1, Phase 2·Recruiting·Listed Nov 2025
LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis
for Metabolic Dysfunction Associated Steatohepatitis (MASH)
Drug: Survodutide
Sites in Orange, Fountain Valley +161 more locations
Sponsor: Boehringer Ingelheim
Sex: All·Age: 18+
Code: NCT06632444·Phase 3·Recruiting·Listed Oct 2024
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
for Breast Cancer
Sites in Orange, Irvine +170 more locations
Sponsor: Stemline Therapeutics, Inc.
Sex: All·Age: 18+
Code: NCT06492616·Phase 3·Recruiting·Listed Jul 2024
A Study of Dotinurad Versus Allopurinol in Tophaceous Gout
for Tophaceous Gout
Drug: Dotinurad
Sites in Orange, Norco +80 more locations
Sponsor: Crystalys Therapeutics
Sex: All·Age: 18 - 75
Code: NCT07089888·Phase 3·Recruiting·Listed Jul 2025
LIVERAGE™ - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Cirrhosis
for Metabolic Dysfunction Associated Steatohepatitis
Drug: Survodutide
Sites in Orange, Fountain Valley +124 more locations
Sponsor: Boehringer Ingelheim
Sex: All·Age: 18+
Code: NCT06632457·Phase 3·Recruiting·Listed Oct 2024
CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis
for Transthyretin Amyloid Cardiomyopathy (ATTR CM)
Drug: Coramitug
Sites in Orange, Pasadena +60 more locations
Sponsor: Novo Nordisk A/S
Sex: All·Age: 18+
Code: NCT07207811·Phase 3·Recruiting·Listed Oct 2025
Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression
for Ovarian Cancer
Drug: INCB123667
Sites in Orange, Fullerton +55 more locations
Sponsor: Incyte Corporation
Sex: Female·Age: 18+
Code: NCT07214779·Phase 3·Recruiting·Listed Oct 2025
A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
for Carcinoma, Non-Small-Cell Lung
Drug: Amivantamab
Sites in Orange, Fullerton +123 more locations
Sponsor: Janssen Research & Development, LLC
Sex: All·Age: 18+
Code: NCT06667076·Phase 2·Recruiting·Listed Oct 2024
A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)
for Melanoma
Sites in Orange, Fullerton +89 more locations
Sponsor: Regeneron Pharmaceuticals
Sex: All·Age: 18+
Code: NCT06246916·Phase 3·Recruiting·Listed Feb 2024
Beamion LUNG-3: Adjuvant Zongertinib vs Standard Treatment in People With Completely Resected Stage II-IIIB NSCLC Harboring Activating HER2 TKD Mutations
for Non-small Cell Lung Cancer
Drug: Zongertinib
Sites in Orange, Glendale +25 more locations
Sponsor: Boehringer Ingelheim
Sex: All·Age: 18+
Code: NCT07195695·Phase 3·Recruiting·Listed Sep 2025
Phase IIIb Study of Ribociclib + ET in Early Breast Cancer
for Early Breast Cancer
Drug: Ribociclib
Sites in Orange, Fullerton +72 more locations
Sponsor: Novartis Pharmaceuticals
Sex: All·Age: 18 - 100
Code: NCT05827081·Phase 3·Recruiting·Listed Apr 2023
Randomized Study in Children and Adolescents With Migraine: Acute Treatment
for Pediatric Migraine
Sites in Orange, Fountain Valley +76 more locations
Sponsor: Pfizer
Sex: All·Age: 6 - 17
Code: NCT04649242·Phase 3·Recruiting·Listed Dec 2020
Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer
for Carcinoma, Non-Small-Cell Lung
Drug: LY3537982
Sites in Orange, Los Angeles +89 more locations
Sponsor: Eli Lilly and Company
Sex: All·Age: 18+
Code: NCT06890598·Phase 3·Recruiting·Listed Mar 2025
A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)
for Crohn's Disease
Drug: Tulisokibart
Sites in Orange, Anaheim +69 more locations
Sponsor: Merck Sharp & Dohme LLC
Sex: All·Age: 16 - 80
Code: NCT06430801·Phase 3·Recruiting·Listed May 2024
A Randomized Study of Azetukalner Versus Placebo in Depressive Episodes Associated With Bipolar I or II Disorder (Bipolar Depression)
for Bipolar Disorder
Sites in Orange, Bellflower +31 more locations
Sponsor: Xenon Pharmaceuticals Inc.
Sex: All·Age: 18 - 74
Code: NCT07172516·Phase 3·Recruiting·Listed Sep 2025
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
for Heart Failure With Preserved Ejection Fraction
Sites in Orange, Huntington Beach +117 more locations
Sponsor: Amgen
Sex: All·Age: 18 - 99
Code: NCT07037459·Phase 3·Recruiting·Listed Jun 2025
A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)
for Metastatic Castration-resistant Prostate Cancer (mCRPC)
Sites in Orange, Irvine +51 more locations
Sponsor: Merck Sharp & Dohme LLC
Sex: All·Age: 18+
Code: NCT06136650·Phase 3·Recruiting·Listed Nov 2023
A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-3)
for Bipolar Disorder Type I With Mania
Drug: KarXT
Sites in Orange, Garden Grove +53 more locations
Sponsor: Bristol-Myers Squibb
Sex: All·Age: 18 - 65
Code: NCT06929273·Phase 3·Recruiting·Listed Apr 2025
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
for Heart Failure
Drug: Empagliflozin
Sites in Orange, Tustin +92 more locations
Sponsor: Boehringer Ingelheim
Sex: All·Age: 18+
Code: NCT06424288·Phase 3·Recruiting·Listed May 2024
A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)
for Endometrial Cancer
Sites in Orange, Irvine +46 more locations
Sponsor: Merck Sharp & Dohme LLC
Sex: Female·Age: 18+
Code: NCT06952504·Phase 3·Recruiting·Listed May 2025
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events
for Diabetes Mellitus, Type 2
Sites in Orange, Long Beach +121 more locations
Sponsor: Cleerly, Inc.
Sex: All·Age: 55+·Accepts healthy volunteers
Code: NCT06112418·Recruiting·Listed Nov 2023
Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease
for Alzheimer Disease
Sites in Orange, Riverside +36 more locations
Sponsor: Lighthouse Pharmaceuticals, Inc.
Sex: All·Age: 55 - 80
Code: NCT06847321·Phase 2·Recruiting·Listed Feb 2025
Phase 2 Study to Evaluate Safety and Efficacy of Cretostimogene Grenadenorepvec in High-Risk NMIBC
for High-Risk Non-Muscle-Invasive Bladder Cancer
Sites in Orange, Irvine +73 more locations
Sponsor: CG Oncology, Inc.
Sex: All·Age: 18+
Code: NCT06567743·Phase 2·Recruiting·Listed Aug 2024
Top Research Study Locations in Orange
Researchers run research studies in Orange, CA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Children's Hospital of Orange County | B Acute Lymphoblastic Leukemia, Neuroblastoma, Recurrent Malignant Solid Neoplasm | 68 |
| UC Irvine Health/Chao Family Comprehensive Cancer Center | Stage IV Colorectal Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Metastatic Malignant Solid Neoplasm | 62 |
| University of California Irvine | Amyotrophic Lateral Sclerosis, Anticoagulants, Carcinoma, Non-Small-Cell Lung | 27 |
| Chao Family Comprehensive Cancer Center, University of California, Irvine | Glioma, Hepatocellular Carcinoma, Pancreatic Cancer | 21 |
| University of California Irvine Medical Center | ARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome | 20 |
| University of California, Irvine | Myasthenia Gravis, Parkinson Disease, Acute Myeloid Leukemia (AML) | 17 |
| UC Irvine Health | Multiple Myeloma, Aortic Stenosis, B-cell Malignancy | 14 |
| UC Irvine Medical Center | Advanced Metastatic Castration Resistant Prostate Cancer, Atrial Fibrillation, Autosomal Dominant Polycystic Kidney Disease | 12 |
| NRC Research Institute | Bipolar Disorder, Bipolar I Disorder, Bipolar Depression | 10 |
| ATP Clinical Research | Bipolar Disorder, Alzheimer's Disease, Bipolar Depression | 9 |
| Chao Family Comprehensive Cancer Center University of California, Irvine | Melanoma (Skin), Cervical Cancer, Chronic Myeloid Leukemia | 8 |
| University of California, Irvine (UCI) Health - UC Irvine Medical Center | Neoplasm Metastasis, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung | 8 |
| University of California, Irvine Medical Center | Cancer, Lung, Cardiovascular Diseases, Colorectal Cancer; Lung Cancer | 8 |
| Children's Hospital Orange County | ALL, AML, Acute Undifferentiated Leukemia | 7 |
| Saint Joseph Hospital - Orange | Advanced Malignant Solid Neoplasm, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8 | 7 |
| UC Irvine Health - Chao Family Comprehensive Cancer Center | Gastric Cancer, Hepatocellular Carcinoma, Acute Myeloid Leukemia | 6 |
| UCI Health | Cancer, Crohn's Disease, Fatigue Related to Cancer Treatment | 5 |
| Chao Family Comprehensive Cancer Center | Chronic Lymphocytic Leukemia, Advanced Clear Cell Renal Cell Carcinoma, Endometrial Cancer | 4 |
| Chao Family Comprehensive Cancer Center, University of California Irvine | Allogeneic Stem Cell Transplantation, Breast Cancer, Colorectal Cancer | 4 |
| Children's Hospital of Orange County (CHOC) | Acute Lymphoblastic Leukemia (ALL), Acute Myelogenous Leukemia (AML or ANLL), Anti-myostatin | 4 |
| Knowledge Research Center | Colonic Polyps, MASH - Metabolic Dysfunction-Associated Steatohepatitis, Metabolic Dysfunction-Associated Steatotic Liver Disease | 4 |
| Neurocrine Clinical Site | Major Depressive Disorder, Bipolar Disorder, Schizoaffective Disorder | 4 |
| UC Irvine | Autoimmune Encephalitis, Encephalitis, Overactive Bladder (OAB) | 4 |
| UCI Medical Center | Deep Venous Thrombosis, Locally Advanced Solid Tumor, Metastatic Solid Tumor | 4 |
| Center for Inherited Blood Disorders | Hemophilia A, Hemophilia B | 3 |
Active & Upcoming Studies in Orange (2026)
Recruiting trials in Orange grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (222 active studies)
- Testing the Effect of Teclistamab on Recurrent Plasmablastic Lymphoma · Phase 1 · National Cancer Institute (NCI)
- Fianlimab&Cemiplimab as TotalNeoadj The (TNT) ForMelanoma · Phase 2 · University of California, Irvine
Cardiovascular (19 active studies)
- Optimal Ventilation for Cardiac Arrest · Children's Hospital of Philadelphia
- EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease · Phase 3 · Boehringer Ingelheim
Mental health & behavior (18 active studies)
- Empowering Patients' Lung Cancer Screening Uptake (Empower LCS/Call+) · University of California, Irvine
- Relapse Prevention Trial Evaluating KarXT Treatment in Schizophrenia · Phase 3 · Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Neurology & pain (18 active studies)
- A Study of Zunveyl on Safety, Tolerability, Neuropsychiatric Symptoms, and Caregiver Distress in Alzheimer's Disease (RESOLVE) · Phase 4 · Alpha Cognition, Inc
- Biofield Therapy for the Support of Immunotherapy-related Symptoms Among Adult Cancer Patients - A Pilot Study · University of California, Irvine
Diabetes & metabolic (14 active studies)
- Efficacy, Safety, and Pharmacokinetics of Tirzepatide (LY3298176) Once Weekly Versus Placebo in Pediatric Participants 6 to Less Than 12 Years of Age Who Have Obesity (ADVANCE-SURMOUNT-KIDS) · Phase 3 · Eli Lilly and Company
- EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease · Phase 3 · Boehringer Ingelheim
Pediatric (8 active studies)
- A Study of the Safety, Dosing, and Delivery of NEO100 in Patients With Pediatric Brain Tumors · Phase 1 · Neonc Technologies, Inc.
- Pediatric Down Syndrome Post-Approval Study · Inspire Medical Systems, Inc.
Vaccines (2 active studies)
- Percutaneous Electrical Nerve Field Stimulation (PENFS) in Patients With Post Concussion Syndrome (PCS) · Children's Hospital of Orange County
- SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry · Massive Bio, Inc.
Eye & vision (1 active study)
- The Myelin Disorders Biorepository Project · Children's Hospital of Philadelphia
Common conditions studied in Orange
- Breast Cancer (9 active studies)
- Ovarian Cancer (9 active studies)
- Acute Myeloid Leukemia (8 active studies)
- Major Depressive Disorder (8 active studies)
- Endometrial Cancer (7 active studies)
- Gastric Cancer (7 active studies)
Leading research sponsors in Orange
- University of California, Irvine
- National Cancer Institute (NCI)
- Children's Oncology Group
- Eli Lilly and Company
- NRG Oncology
Frequently asked questions
How many paid clinical trials are currently recruiting in Orange?
There are approximately 517 recruiting clinical trials in Orange, California listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Orange pay participants?
Most recruiting trials in Orange compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Orange?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Orange?
The most common conditions under active study in Orange include Breast Cancer (9), Ovarian Cancer (9), Acute Myeloid Leukemia (8), Major Depressive Disorder (8), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Orange?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Orange on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Orange?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Orange?
Recruiting research sites in Orange include Children's Hospital of Orange County, UC Irvine Health/Chao Family Comprehensive Cancer Center, University of California Irvine, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Orange right now?
The largest active categories in Orange are Cancer & tumors (222), Cardiovascular (19), Mental health & behavior (18). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
Browse more clinical trials
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