Intraoperative Microelectrode Recordings Using MAVEN Compared to Standard Recording Apparatuses

Part of paid clinical trials in Rochester, Minnesota.

Sponsor: Mayo Clinic
Study ID: NCT07868614
Status: Recruiting

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Conditions

Dystonia
Essential Tremor
Parkinson's Disease

Eligibility Criteria

Sex: ALL
Age: 18 Years - N/A
Healthy Volunteers: Not accepted

Interventions

Multifunctional Apparatus for Voltammetry, Electrophysiology, and Neuromodulation (MAVEN) — DEVICE
During deep brain stimulation (DBS) surgery, the MAVEN device will be used in parallel with the currently used Alpha Omega Device to compare the quality of electrophysiologic readings.

Study Details

The purpose of this research is to determine if the electrophysiologic data collected from standard-of-care microelectrode recordings during human deep brain stimulation (DBS) surgery will be the same using the MAVEN device compared with the standard Alpha Omega device with either a tungsten standard-of-care microelectrode (for microelectrode recordings), or a carbon-fiber microelectrode (for neurotransmitter recordings). The number of microelectrodes used for both the tungsten and the carbon-fiber version will be the same as the standard-of-care.

Key Dates

First listed: Oct 9, 2026
Start date: Jul 29, 2025
Status verified: Oct 2026
Primary completion: Dec 1, 2028
Completion: Dec 1, 2028

Study Design

Enrollment: 30 participants (estimated)

Arms

Arm: Tungsten fiber microelectrode
Standard of care Tungsten microelectrode and cables will be utilized, and a splitter adaptor cable will route the data to both the standard Alpha Omega device and also to MAVEN, for comparison of MER readings.
Arm: Carbon fiber microelectrode
A carbon fiber microelectrode will be utilized (in lieu of the tungsten microelectrode) and a splitter adaptor cable will route the data to both the standard Alpha Omega device and also to MAVEN, for comparison of MER readings.