As of September 2026, 1,216 paid clinical trials are recruiting in Rochester, Minnesota. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Rochester offers studies at sites including Mayo Clinic for conditions such as Malignant Solid Neoplasm, Breast Cancer, Heart Failure, Ovarian Cancer. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
Researchers run research studies in Rochester, MN at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Mayo Clinic | Heart Failure, Breast Cancer, Ovarian Cancer | 461 |
| Mayo Clinic in Rochester | Malignant Solid Neoplasm, Hematopoietic and Lymphatic System Neoplasm, Breast Carcinoma | 397 |
| Mayo Clinic Rochester | Chronic Lymphocytic Leukemia, CRC, Colorectal Cancer | 80 |
| Mayo Clinic - Rochester | Endometrial Cancer, Epilepsy, Epilepsy (Treatment Refractory) | 31 |
| Mayo Clinic Minnesota | Healthy, Advanced Melanoma, Aging | 27 |
| Mayo Clinic in Rochester, Minnesota | Breast Neoplasms, Multiple Myeloma, Neoplasm Metastasis | 13 |
| Mayo Clinic, Rochester | Interstitial Lung Diseases, Acute Kidney Failure, Acute Kidney Insufficiency | 11 |
| Mayo Clinic Cancer Center | Lung Cancer, PDAC, PDAC - Pancreatic Ductal Adenocarcinoma | 7 |
| Clinical Trial Site | Advanced Hepatocellular Carcinoma, End Stage Renal Disease, Hereditary Transthyretin-Mediated Amyloidosis With Polyneuropathy | 5 |
| Mayo Clinic (Data Collection Only) | Adult T-cell Leukemia/Lymphoma, Aggressive NK-cell Leukemia, Anaplastic Large Cell Lymphoma, ALK-Positive | 4 |
| Mayo Clinic Cancer Center Outpatient Pharmacy | Colorectal Neoplasms, Advanced Renal Cell Carcinoma, Advanced or Metastatic Renal Cell Carcinoma | 4 |
| Mayo Clinic Comprehensive Cancer Center | Acute Myeloid Leukemia, Adenocarcinoma, Adenocarcinoma of Colon | 4 |
| Mayo Clinic in Minnesota | Advanced Solid Tumor, Colorectal Cancer (CRC), Cutaneous Melanoma | 4 |
| GSK Investigational Site | Amyloidosis, Gastrointestinal Neoplasms, Neoplasms, Prostate | 3 |
| Mayo Clinic - PPDS | Alpha1-Antitrypsin Deficiency, Metastatic HER2-positive Breast Cancer, Uveal Melanoma | 3 |
| Mayo Clinic Hospital | ADA SCID, Glioblastoma, Glioblastoma (GBM) | 3 |
| Mayo Clinic- Rochester | Aneurysmal Subarachnoid Hemorrhage (aSAH), Cerebral Vasospasm, Crohns Disease | 3 |
| Mayo Rochester | Advanced Solid Tumor, Adult, Breast Cancer, Cervical Cancer | 3 |
| The Mayo Clinic | FIGO Stage III and IV Ovarian Cancer, Fallopian Tube Cancers, Long-COVID | 3 |
| 89bio Clinical Study Site | Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis, Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis | 2 |
| Crinetics Study Site | Classic Congenital Adrenal Hyperplasia, Congenital Adrenal Hyperplasia, Neuroendocrine Neoplasm | 2 |
| Mayo Clinic - PIN | Crohn's Disease (CD), Obesity, Overweight | 2 |
| Mayo Clinic - Rochester Minnesota | Intermediate Risk Non-Muscle Invasive Bladder Cancer, Low-grade Upper Tract Urothelial Carcinoma | 2 |
| Mayo Clinic Children's - PIN | Developmental and Epileptic Encephalopathy, Dravet Syndrome | 2 |
| Mayo Clinic Department of Ophthalmology | Amblyopia | 2 |
Recruiting trials in Rochester grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
There are approximately 1,216 recruiting clinical trials in Rochester, Minnesota listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Most recruiting trials in Rochester compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
The most common conditions under active study in Rochester include Malignant Solid Neoplasm (18), Breast Cancer (15), Heart Failure (15), Ovarian Cancer (15), among many others. Browse the list above to explore every recruiting trial.
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Rochester on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Recruiting research sites in Rochester include Mayo Clinic, Mayo Clinic in Rochester, Mayo Clinic Rochester, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
The largest active categories in Rochester are Cancer & tumors (381), Cardiovascular (92), Neurology & pain (68). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.