Crohn's disease Clinical Trials

Recruiting crohn's disease studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat crohn's disease. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting crohn's disease studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting crohn's disease trials

Within

ACT for Veterans With IBD and Mental Health Challenges

for Inflammatory Bowel Diseases

1 site in Houston

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT07397195

Digital Mind Body Intervention Among Black and Hispanic Patients Living With Inflammatory Bowel Disease

for Crohn's Disease

1 site in The Bronx

Sponsor: Montefiore Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06510296

Medical Treatment Versus Surgery in Stricturing Small Bowel Crohn's Disease

for Crohn Disease

Sponsor: Nantes University Hospital

Sex: All·Age: 18 - 70

Code: NCT05584228

Emerging Indications for Hyperbaric Oxygen Treatment

for Post-COVID-19 Condition

Sponsor: Jay C. Buckey Jr.

Sex: All·Age: All ages

Code: NCT07240649·Phase 4

Treatment of Chinese Adult Subjects With Moderate to Severe Crohn's Disease With Tabellvi®

for Crohn's Disease

Sponsor: Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Sex: All·Age: 18 - 70

Code: NCT07663526·Phase 4

Online Pain Education for Crohn's Disease and Ulcerative Colitis

for Crohn's Disease

1 site in Los Angeles

Sponsor: Cedars-Sinai Medical Center

Sex: All·Age: 18+

Code: NCT07671313

Efficacy and Safety of CDED With Anti-TNF-α Biologics in Crohn's Disease

for Crohn Disease

Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University

Sex: All·Age: 18+

Code: NCT07344428

Retrospective Observational Multicenter Study on the Treatment Patterns, Extra-Intestinal Manifestations, Resource Utilisation, and Outcomes of Patients With Inflammatory Bowel Disease in Dutch Hospitals

for Crohn Disease

Sponsor: LOGEX

Sex: All·Age: 18+

Code: NCT07682038

Developing a Self-Management Intervention to Improve Health Outcomes for Patients With Inflammatory Bowel Disease

for Inflammatory Bowel Diseases

1 site in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT07456566

Longitudinal Immunophenotyping of Patients With Inflammatory Bowel Disease

for Inflammatory Bowel Disease

1 site in Bethesda

Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Sex: All·Age: 18 - 85

Code: NCT07619547

Study of Advanced Therapies for the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease or Ulcerative Colitis

for Crohn's Disease

9 sites incl. Lakeland

Sponsor: AbbVie

Sex: All·Age: 18 - 75

Code: NCT07697456·Phase 2

A Study on Infections in Adults With Ulcerative Colitis/Crohn's Disease

for Ulcerative Colitis

1 site in Cambridge

Sponsor: Takeda

Sex: All·Age: 65+

Code: NCT07250815

A Study of Zasocitinib (TAK-279) in Adults With Active Crohn's Disease

for Crohn's Disease

Sponsor: Takeda

Sex: All·Age: 18 - 75

Code: NCT07403968·Phase 2

A Phase II Study of H021 Enteric-coated Tablets for Moderately to Severely Active Crohn's Disease

for Crohn's Disease

3 sites incl. Hamden

Sponsor: Jiangsu Carephar Pharmaceutical Co., Ltd.

Sex: All·Age: 18 - 75

Code: NCT07677514·Phase 2

Stopping PPI Therapy in Inactive IBD

for Ulcerative Colitis (UC)

Sponsor: University of Nottingham

Sex: All·Age: 16+

Code: NCT07691138·Phase 4

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A Study of Guselkumab in Participants With Crohn's Disease and Ulcerative Colitis

for Crohn Disease

Sponsor: Janssen-Cilag Pharma GmbH

Sex: All·Age: 18+

Code: NCT07606339

NaviCam Patency Capsule to Verify Gastrointestinal Patency

for Intestinal Stricture

1 site in Downers Grove

Sponsor: AnX Robotica Corp.

Sex: All·Age: 22+

Code: NCT07649720

A Study to Assess Concentration of TREMFYA in Breast Milk of Lactating Women Who Are Receiving TREMFYA Therapeutically

for Psoriasis

1 site in Chapel Hill

Sponsor: Janssen Research & Development, LLC

Sex: Female·Age: 18+

Code: NCT07654751·Phase 4

A Study of JNJ-78934804 in Participants With Moderately to Severely Active Crohn's Disease

for Crohn Disease

6 sites incl. Anaheim

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07577843·Phase 3

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A Study to Investigate the Long-term Safety, Tolerability and Efficacy of Balinatunfib in Participants With Crohn's Disease or Ulcerative Colitis (SPECIFI-IBD-LTS)

for Colitis Ulcerative

Sponsor: Sanofi

Sex: All·Age: 19 - 77

Code: NCT07222189·Phase 2

A Real-World Study of Guselkumab in Ulcerative Colitis and Crohn's Disease in Saudi Arabia

for Colitis

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07541261

Apply to this trial

A Master Protocol (IIBD): A Study of Multiple Drugs in Adults With Ulcerative Colitis or Crohn's Disease

for Colitis, Ulcerative

15 sites incl. Scottsdale

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 80

Code: NCT07483073·Phase 2

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A Study of LY4395089 and Mirikizumab (LY3074828) Given Together and Mirikizumab (Alone) in Adults With Crohn's Disease

for Crohn Disease

15 sites incl. Scottsdale

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 80

Code: NCT07483099·Phase 2

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Development of the SC-IBD Self-Care Measurement Scale

for Inflammatory Bowel Diseases

Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Sex: All·Age: 18+

Code: NCT07494227

A Study of Guselkumab Versus Risankizumab in Participants With Moderately to Severely Active Crohn's Disease

for Crohn Disease

24 sites incl. Dothan

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07499232·Phase 3

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Open-label Single-arm Study to Assess the Efficacy of Mirikizumab in Patients With Inflammatory Strictures Due to CD

for Crohn Disease

1 site in Orlando

Sponsor: Alimentiv Inc.

Sex: All·Age: 18+

Code: NCT06997965·Phase 4

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Real-World Study of IL-23 Inhibitors in Active Crohn's Disease

for Crohn's Disease

Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University

Sex: All·Age: 18 - 75

Code: NCT07545317

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A Study to Assess Real-world Outcomes for Long-Term Use of Guselkumab

for Inflammatory Bowel Disease

Sponsor: Janssen-Cilag A.G., Switzerland

Sex: All·Age: 18+

Code: NCT07532213

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Palmitoleic Acid Combined With Infliximab for Promoting Intestinal Mucosal Healing in Crohn's Disease

for Crohn's Disease

Sponsor: Chinese Medical Association

Sex: All·Age: 18 - 75

Code: NCT07417696·Phase 4

Thermal Measurements of the Gut With a Colonoscope Compatible Thermal Probe

for Inflammatory Bowel Diseases

1 site in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT07352995

Partial Enteral Nutrition to Prevent Weight Loss and Sarcopenia in IBD Patients at Nutritional Risk - SIMBA

for Ulcerative Colitis (Disorder)

Sponsor: Lionhealth Srl Società Benefit

Sex: All·Age: 18 - 65

Code: NCT07433946

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Impact of Prior Identification and Education of Patients Requiring a Digestive Stoma for Fecal Diversion

for Colorectal Anastomosis

Sponsor: Assistance Publique Hopitaux De Marseille

Sex: All·Age: 18+

Code: NCT06881303

Lipopolysaccharide Adsorption (Efferon LPS) in Patients With Ulcerative Colitis and Crohn Disease

for Crohn Disease

Sponsor: Efferon JSC

Sex: All·Age: 18 - 65

Code: NCT07383597

A Retrospective Study to Evaluate Treat-to-Target and Disease Modification in Adult Participants With Crohn's Disease and Ulcerative Colitis in Real World Setting

for Crohn's Disease

Sponsor: AbbVie

Sex: All·Age: 20+

Code: NCT07421258

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Comparison of Quality of Life During a Flare of Crohn's Disease Treated With Prednisolone or aCDED With PEN in Adult Patients

for Crohn Disease

Sponsor: University Hospital Tuebingen

Sex: All·Age: 18+

Code: NCT06953791·Phase 2

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68Ga-FAPI-46 PET/CT for Assessing Small Bowel Fibrostenosis in Crohn's Disease

for Crohn's Disease

1 site in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07273188·EARLY_Phase 1

Apply to this trial

A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease

for Crohn's Disease

22 sites incl. Colorado Springs

Sponsor: Sanofi

Sex: All·Age: 16 - 80

Code: NCT07184944·Phase 3

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Impact Of The Gut Microbiota On Host Cells Energy Metabolism in Health And In Inflammatory Bowel Disease

for IBD

Sponsor: Assistance Publique - Hôpitaux de Paris

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT07300553·Phase 2

Apply to this trial

Repetitive Transcranial Magnetic Stimulation Combined With Anti-inflammatory Diet in Crohn's Disease

for Crohn's Disease

Sponsor: Cairo University

Sex: All·Age: 40 - 60

Code: NCT07531342

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A Study to Evaluate the Efficacy of Guselkumab in Chinese Participants With Crohn's Disease (CD)

for Crohn Disease

Sponsor: Xian-Janssen Pharmaceutical Ltd.

Sex: All·Age: 18+

Code: NCT07310095·Phase 4

Apply to this trial

The Effect of Vascular Imaging Devices on Success Rates of Peripheral Vascular Access in Pediatric Patients

for Peripheral Vascular Access in Pediatric Patients

Sponsor: Sibel Seçkin Pehlivan

Sex: All·Age: 0 Days - 18 Days

Code: NCT07315711

A Study to Observe Real-world Evidence of Guselkumab Treatment in Participants With Ulcerative Colitis and Crohn's Disease in the United Kingdom (UK)

for Inflammatory Bowel Disease

Sponsor: Janssen-Cilag Ltd.

Sex: All·Age: 18+

Code: NCT07242248

Apply to this trial

COMPARE - Pediatric Inflammatory Bowel Disease (PIBD)

for Ulcerative Colitis, Pediatric

4 sites incl. Chapel Hill

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: 1 - 18

Code: NCT07198113

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Epidemiological Characteristics and Efficacy Evaluation of Difficult-To-Treat Crohn's Disease

for Crohn Disease

Sponsor: Xiang Gao

Sex: All·Age: 18 - 65

Code: NCT07364734

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Cranberry and Gut Health in Crohn's Disease

for Crohn Disease (CD)

1 site in Worcester

Sponsor: Ana Maldonado-Contreras

Sex: All·Age: 18 - 65

Code: NCT07170462·EARLY_Phase 1

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A Long-Term Extension Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis (UC) or Crohn's Disease (CD)

for Ulcerative Colitis

14 sites incl. Phoenix

Sponsor: Takeda

Sex: All·Age: 2 - 17

Code: NCT06405087·Phase 3

Apply to this trial

Risankizumab for Fibrostenotic Crohn's Disease Treatment

for Crohn Disease

Sponsor: First Affiliated Hospital of Wenzhou Medical University

Sex: All·Age: 18 - 80

Code: NCT07177118·Phase 3

Personalized Risk Estimation for Crohn's Disease (PRE-Crohn's): Implementation and Feasibility

for Inflammatory Bowel Diseases

1 site in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 14+·Accepts healthy volunteers

Code: NCT05332639

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A Study of Icotrokinra in Participants With Moderately to Severely Active Crohn's Disease

for Crohn Disease

55 sites incl. Chandler

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07196722·Phase 2, Phase 3

Apply to this trial

An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease

for Crohn's Disease

94 sites incl. Peoria

Sponsor: Sanofi

Sex: All·Age: 16 - 80

Code: NCT07184931·Phase 3

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Evaluation of a Multimodal Day Hospital for the Overall Management of Patients With Chronic Inflammatory Bowel Diseases (IBD)

for Inflammatory Bowel Disease (IBD)

Sponsor: Assistance Publique - Hôpitaux de Paris

Sex: All·Age: 18+

Code: NCT07167186

Evaluation of a Remote Monitoring Application in the Follow-up of Patients With Active Inflammatory Bowel Diseases

for Crohn Disease

Sponsor: Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives

Sex: All·Age: 18 - 80

Code: NCT06742385

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Safety of Mesentery-embedding Surgery in Patients With Ileocolic Crohn's Disease on Biotherapy

for Crohn Disease

Sponsor: Centre Hospitalier Universitaire de Nīmes

Sex: All·Age: 18+

Code: NCT06856044

Apply to this trial

MOdel-Informed Precision Dosing of Ustekinumab and VEdolizumab in Inflammatory Bowel Disease

for Inflammatory Bowel Diseases

Sponsor: Odense University Hospital

Sex: All·Age: 18+

Code: NCT06788340·Phase 4

A Study to Generate Real-world Evidence of Guselkumab Effectiveness in Inflammatory Bowel Disease in Germany

for Inflammatory Bowel Disease

Sponsor: Janssen-Cilag G.m.b.H

Sex: All·Age: 18+

Code: NCT07102368

Apply to this trial

Phase 1b/2a Trial of Allogeneic HSCT From an HLA-partially Matched Related or Unrelated Donor After TCRab+ T-cell/CD19+ B-cell Depletion for Patients With Monogenic and/or Early-onset Medically Refractory Crohn Disease

for Crohn Disease

1 site in Palo Alto

Sponsor: Stanford University

Sex: All·Age: 2 - 30

Code: NCT06986382·Phase 1, Phase 2

Study of Tissue Repair in Inflammatory Bowel Disease Exploiting Organoid Technology

for Crohn Disease

Sponsor: Assistance Publique Hopitaux De Marseille

Sex: All·Age: 18+

Code: NCT06805890

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A Study to Assess the Effectiveness of Second-Line Therapy of Upadacitinib and Risankizumab in Adult Participants With Crohn's Disease in a Real-World Setting

for Crohn's Disease

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07073079

Apply to this trial

Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

for Crohn's Disease

35 sites incl. Dothan

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 70

Code: NCT06937099·Phase 3

Apply to this trial

A Phase 2 Study to Evaluate Therapies for Inflammatory Bowel Disease

for Inflammatory Bowel Disease (IBD)

46 sites incl. Birmingham

Sponsor: Mirador Therapeutics, Inc.

Sex: All·Age: 18 - 80

Code: NCT07113522·Phase 2

Apply to this trial

Crohn's disease clinical trials — common questions

Are crohn's disease clinical trials free to join?

Yes. Participating in a crohn's disease clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a crohn's disease clinical trial?

Each crohn's disease study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a crohn's disease trial near me?

Use the location controls above. We'll show recruiting crohn's disease trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many crohn's disease trials are recruiting right now?

We're currently tracking roughly 82 recruiting crohn's disease trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Crohn's disease trials by city

Boston, MA Los Angeles, CA Birmingham, AL La Jolla, CA Anaheim, CA Ann Arbor, MI Colorado Springs, CO Downers Grove, IL

Related specialties

Gastroenterology Inflammatory bowel disease Autoimmune disease