End-stage renal disease Clinical Trials

Recruiting end-stage renal disease studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat end-stage renal disease. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting end-stage renal disease studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting end-stage renal disease trials

Within

BicMag Study - Improving Mineral Buffering Capacity in Dialysis Patients

for End Stage Renal Disease

Sponsor: Elisabethinen Hospital

Sex: All·Age: 18+

Code: NCT07663279

Development and Test of a Communication Skills Training for Transplant Providers - Aims 2 & 3

for Kidney Disease, Chronic

2 sites incl. Livingston

Sponsor: Temple University

Sex: All·Age: 18 - 80

Code: NCT06182475

Pumpkin Seed Oil as a Nutraceutical for Hemodialysis Patients

for End Stage Renal Disease

Sponsor: Al-Mustansiriyah University

Sex: All·Age: 18+

Code: NCT07710183

Apply to this trial

Study of ChoironeX GalKO Porcine Thymokidney Xenotransplantation in End-Stage Renal Disease

for End Stage Renal Disease

2 sites in New York

Sponsor: Xeno Holdings (US), LLC dba ChoironeX

Sex: All·Age: 18 - 70

Code: NCT07696962·Phase 1

Bupropion for Fatigue in End-stage Kidney Disease Patients on Hemodialysis

for End Stage Renal Disease

1 site in San Antonio

Sponsor: The University of Texas Health Science Center at San Antonio

Sex: All·Age: 25 - 74

Code: NCT06609343·Phase 1, Phase 2

The Effect of Intradialytic Eye Exercise in Hemodialysis Patients

for End Stage Renal Disease

Sponsor: Pardis Specialized Wellness Institute

Sex: All·Age: 18 - 80

Code: NCT07591714

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Impact on Quality of Life of Symptoms Routine E-monitoring Among Dialysis Patients.

for End Stage Renal Disease

Sponsor: Central Hospital, Nancy, France

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06257134

Apply to this trial

Solv Multi-Pass Hemodialysis System In-Center Clinical Study

for End Stage Renal Disease

1 site in Greenville

Sponsor: Mozarc Medical US LLC

Sex: All·Age: 18+

Code: NCT07216885

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Comparison of Individualized Sodium Management Versus Standard Treatment in Hemodialysis

for End Stage Renal Disease

Sponsor: Fresenius Medical Care Deutschland GmbH

Sex: All·Age: 18+

Code: NCT06341452

Apply to this trial

Drug Interaction Potential of Pro-Inflammatory Conditions

for Diabetes Mellitus, Type 2

1 site in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 12 - 99

Code: NCT07360938

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PReSeRVE-HD: Observational Study of the Merit HeRO® Graft and Super HeRO® in Patients on Hemodialysis

for End Stage Renal Disease

7 sites incl. Washington D.C.

Sponsor: Merit Medical Systems, Inc.

Sex: All·Age: 18+

Code: NCT06422871

Apply to this trial

Blood Flow Conditions and Sounds in AVFs

for End Stage Renal Disease

Sponsor: Mario Negri Institute for Pharmacological Research

Sex: All·Age: 18 - 90

Code: NCT06411353

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Ventilatory Functions and Physical Intolerance in ESRD Adolescents: Response to Program of Walking With Dogs

for End Stage Renal Disease

Sponsor: Cairo University

Sex: All·Age: 13 - 17

Code: NCT06861816

Apply to this trial

CAPABLE Transplant

for Quality of Life

1 site in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18 - 99

Code: NCT06326905

Apply to this trial

Post Market Study for VasQ, an External Support Implant for Arteriovenous Fistula

for End Stage Renal Disease

8 sites incl. Long Beach

Sponsor: Laminate Medical Technologies

Sex: All·Age: 18 - 80

Code: NCT06516653

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Development of an Innovative Hemodialysis Method to Improve Dialytic Clearance of Protein-bound Uremic Toxins

for End Stage Renal Disease

Sponsor: Hospices Civils de Lyon

Sex: All·Age: 18+

Code: NCT06595680·Phase 2

Xeltis Hemodialysis Access (aXess) Conduit: aXess-E Study

for End Stage Renal Disease

Sponsor: Xeltis

Sex: All·Age: 18+

Code: NCT06329310

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The 2-minute Walk Test in Hemodialysis Patients

for End Stage Renal Disease

Sponsor: Kirsehir Ahi Evran Universitesi

Sex: All·Age: 18 - 80

Code: NCT06650215

Xeltis Hemodialysis Access Graft (aXess) US Study

for End Stage Renal Disease

7 sites incl. Phoenix

Sponsor: Xeltis

Sex: All·Age: 18+

Code: NCT06494631

PMR vs MM for Patients on Hemodialysis

for End Stage Renal Disease

Sponsor: Jordan University of Science and Technology

Sex: All·Age: 18+

Code: NCT06625125

Oral Intradialytic Amino Acid Supplementation to Vitalize End-stage Kidney Disease Patients on Hemodialysis

for End Stage Renal Disease

1 site in San Antonio

Sponsor: The University of Texas Health Science Center at San Antonio

Sex: All·Age: 18 - 64

Code: NCT05705414·EARLY_Phase 1

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Study of the Quality of Life in School Aged-children With Posterior Urethral Valves

for Quality of Life

Sponsor: Hospices Civils de Lyon

Sex: Male·Age: 6 - 17

Code: NCT06439862

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Cardio-Renal Registry

for End Stage Renal Disease

Sponsor: Queen Mary University of London

Sex: All·Age: 16+

Code: NCT06521801

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An Extension to Assess the Effect of Expanded Dialysis on Patient Reported Symptoms Using LEVIL

for End Stage Renal Disease

Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Sex: All·Age: 18+

Code: NCT06032208

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Maturation of Arteriovenous Fistula With Automated Sonography Assessments Trial

for Diabetes

20 sites incl. Dothan

Sponsor: Sonavex, Inc.

Sex: All·Age: 18 - 84

Code: NCT06190717

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Safety and Efficacy of Empagliflozin in Hemodialysis

for End Stage Renal Disease

2 sites incl. Boston

Sponsor: NYU Langone Health

Sex: All·Age: 18+

Code: NCT05786443·Phase 2

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SAVE-FistulaS: the SelfWrap-Assisted ArterioVEnous Fistulas Study

for Chronic Kidney Diseases

28 sites incl. Bullhead City

Sponsor: VenoStent

Sex: All·Age: 18+

Code: NCT06001827

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Endoscopic Sleeve Gastroplasty With Endomina® for the Treatment of Obesity in Kidney Transplant Candidates

for Obesity, Morbid

Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Sex: All·Age: 18 - 70

Code: NCT05917795

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CoQ10 and Exercise for Mitochondrial Dysfunction in Advance Kidney Disease

for End Stage Renal Disease

2 sites incl. Sacramento

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18 - 75

Code: NCT05422534·Phase 3

Apply to this trial

Acoustic Analysis of VA Sounds

for End Stage Renal Disease

Sponsor: Mario Negri Institute for Pharmacological Research

Sex: All·Age: 18 - 90

Code: NCT05612022

Apply to this trial

Preference of Life-Sustaining Treatment Among Patients With End Stage Renal Disease

for End Stage Renal Disease

Sponsor: National Taiwan University Hospital

Sex: All·Age: 20+

Code: NCT05878171

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Rheopheresis as Adjuvant Treatment of Calciphylaxis

for Metabolic Disorder

Sponsor: University Hospital, Lille

Sex: All·Age: 18+

Code: NCT04654000

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Efficacy and Safety of XyloCore Peritoneal Dialysis Solution.

for End Stage Renal Disease

Sponsor: Iperboreal Pharma Srl

Sex: All·Age: 18+

Code: NCT03994471·Phase 3

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Retrospective Analysis of Performance and Treatment Data Collected for Genius SleddFlux Filter, Ultraflux AV 600 S Filter & Genius 90 Concentrates in Haemodialysis Patients

for Renal Failure

Sponsor: Fresenius Medical Care Deutschland GmbH

Sex: All·Age: 18+

Code: NCT05282732

Apply to this trial

CKD Specific Telemonitoring Platform to Minimize Adverse Outcomes in High Risk CKD Patients

for Chronic Kidney Disease Stage 5

Sponsor: University of Manitoba

Sex: All·Age: 18+

Code: NCT05726526

Apply to this trial

Tulane Abdominal Transplant Institute (TATI) of Solid Organ Transplantation of HIV-Positive Recipients From HIV-Positive Donors

for Human Immunodeficiency Virus

1 site in Metairie

Sponsor: Tulane University

Sex: All·Age: 18+

Code: NCT05159466

Apply to this trial

Intravascular Ultrasound in Patients With End-stage Renal Disease on Dialysis

for End Stage Renal Disease

1 site in Boston

Sponsor: Boston Medical Center

Sex: All·Age: 18 - 85

Code: NCT04399941

Apply to this trial

Safety & Efficacy of DCR-PHXC in Patients With PH1 and ESRD

for Primary Hyperoxaluria Type 1

1 site in Rochester

Sponsor: Dicerna Pharmaceuticals, Inc., a Novo Nordisk company

Sex: All·Age: All ages

Code: NCT04580420·Phase 2

Apply to this trial

Blood Pressure Slopes and Ultrafiltration in Hemodialysis Patients

for End Stage Renal Disease

1 site in Dallas

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT04163614

Apply to this trial

AMSC for Reducing Anastomotic Stenosis in Primary Arteriovenous Anastomoses

for End Stage Renal Disease

1 site in Jacksonville

Sponsor: Houssam Farres, M.D.

Sex: All·Age: 18 - 85

Code: NCT04392206·Phase 1

Apply to this trial

The Effect of a Prehabilitation Exercise Program on Physical Functioning for Patients Undergoing Kidney Transplantation

for End Stage Renal Disease

Sponsor: University of British Columbia

Sex: All·Age: 19+

Code: NCT04044963

Apply to this trial

Impact of Envarsus XR® on Kidney Biopsy Subclinical Rejection and Blood Immunologic Profile

for End Stage Renal Disease

1 site in Lexington

Sponsor: Roberto Gedaly

Sex: All·Age: 18 - 75

Code: NCT03321656·Phase 2, Phase 3

Apply to this trial

Dissemination of the Donor Application: Utilizing Social Media to Identify Potential Live Organ Donors

for End Stage Renal Disease

6 sites incl. San Diego

Sponsor: Johns Hopkins University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT03803423

Apply to this trial

Partners Calciphylaxis Biobank

for Calciphylaxis

1 site in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT03032835

Apply to this trial

End-stage renal disease clinical trials — common questions

Are end-stage renal disease clinical trials free to join?

Yes. Participating in a end-stage renal disease clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a end-stage renal disease clinical trial?

Each end-stage renal disease study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a end-stage renal disease trial near me?

Use the location controls above. We'll show recruiting end-stage renal disease trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many end-stage renal disease trials are recruiting right now?

We're currently tracking roughly 24 recruiting end-stage renal disease trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

End-stage renal disease trials by city

Boston, MA Indianapolis, IN Jacksonville, FL Long Beach, CA Sacramento, CA San Diego, CA

Related specialties

Nephrology Kidney disease