Paid Clinical Trials in Sacramento, CA
As of August 2026, 583 paid clinical trials are recruiting in Sacramento, California. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Sacramento offers studies at sites including University of California Davis Comprehensive Cancer Center for conditions such as Breast Cancer, Heart Failure, Acute Myeloid Leukemia, Atopic Dermatitis. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Sacramento
Trials by drug in Sacramento
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Newly added in Sacramento
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
Supporting Mental Health and Reducing Care Stress in Caregivers of Persons With Cardiovascular Disease
Post-market Cosmetic Evaluation of Ariessence™ Pure PDGF+ Following Ablative Laser
Renal Impairment Study for Oral EC5026
Evaluation of YB-101 for Safety, Tolerability, Pharmacokinetics, and Efficacy in Graves' Disease
UHFUS Characterization of Normal Lymphatic Anatomy
516 clinical trials
A Study to Evaluate Efficacy, Safety, and Immunogenicity With ABP 938 8 mg Versus EYLEA® HD (Aflibercept) in Participants With Neovascular Age-related Macular Degeneration
A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).
A Phase 2b Study of the Effects of Camoteskimab in Adults With Moderate-to-Severe Atopic Dermatitis
A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated
A Phase 2/3 Study of Brepocitinib in Adults With Lichen Planopilaris
COMO: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)
Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS)
Study to Evaluate the Safety and Efficacy of Larsucosterol in Participants With Alcohol-associated Hepatitis (AH)
A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin
A Phase 3 Trial to Compare IV BCV Versus IV CDV for Treatment of Adenovirus Infection After Allo-HCT
A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes
A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC Alone in Participants With Recurrent/Metastatic Head and Neck Cancer
A Study to Learn About a Clostridioides Difficile Vaccine in People 65 Years of Age and Older
A Study to Investigate Safety and Efficacy of Tapinarof Cream, 1% in Participants Ages 3 Months to < 24 Months With Atopic Dermatitis
A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)
A 16-Week Study to Learn About the Study Medicine Called Ritlecitinib in Adults With Long Lasting Painful Red Skin Lumps, Known by the Medical Term, Hidradenitis Suppurativa, or HS.
GATEWAY: Safety Evaluation of the MiniMed™ NMX8-AID System in Children and Adults Living With Diabetes
A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract
An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease
A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)
ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer
Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants With Psoriasis (PRAGMATYK)
A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)
A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1-Mediated Proteinuric Kidney Disease
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy
MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in People With Multiple Myeloma (MM) That Has Come Back After Taking Other Treatments (Including Prior Treatment With an Anti-CD38 Antibody and Lenalidomide)
A Study of ZL-1310 Versus Investigator's Choice of Therapy in Participants With Relapsed Small Cell Lung Cancer (DLLEVATE)
Phase IIIb Study of Ribociclib + ET in Early Breast Cancer
Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer
A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids)
Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD)
A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised
Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL
Evaluation of Efficacy and Safety of Suzetrigine for Pain Associated With Diabetic Peripheral Neuropathy
A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)
A Study to Evaluate Efficacy of Remibrutinib Compared to Dupilumab at Early Timepoints in Adults With Chronic Spontaneous Urticaria Inadequately Controlled by Second Generation H1-antihistamines
Top Research Study Locations in Sacramento
Researchers run research studies in Sacramento, CA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of California Davis Comprehensive Cancer Center | Stage IV Lung Cancer AJCC v8, Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia | 91 |
| UC Davis Medical Center | Heart Failure, Intracerebral Hemorrhage, Acute Decompensated Heart Failure | 38 |
| University of California, Davis | Duchenne Muscular Dystrophy, Amblyopia, Amyotrophic Lateral Sclerosis | 38 |
| Mercy Cancer Center - Sacramento | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8 | 34 |
| Kaiser Permanente Downtown Commons | Lung Non-Small Cell Carcinoma, Stage IIIB Lung Cancer AJCC v8, Stage IV Lung Cancer AJCC v8 | 31 |
| Sutter Medical Center Sacramento | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8 | 31 |
| Kaiser Permanente-South Sacramento | Breast Cancer, Lung Non-Small Cell Carcinoma, Stage IIIB Lung Cancer AJCC v8 | 30 |
| UC Davis Health | Heart Failure, Acinetobacter Baumannii-calcoaceticus Complex Infection (ABC), Acute Pain | 22 |
| University of California Davis | Adenovirus Infections, Advanced Lung Carcinoma, Breast Cancer | 20 |
| UC Davis | Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Autoimmune Encephalitis | 13 |
| University of California, Davis Comprehensive Cancer Center | Advanced Solid Tumor, Colorectal Cancer, Locally Advanced Solid Tumor | 12 |
| University of California Davis Health | Articular Cartilage Defect, Articular Cartilage Disorder of Knee, Breast Cancer | 11 |
| UC Davis Comprehensive Cancer Center | Abdominal Neoplasm, Advanced Solid Tumors, Avascular Necrosis | 10 |
| University of California Davis Medical Center | Bariatric Surgery Candidate, Cardiovascular Diseases, Connective Tissue Diseases | 10 |
| South Sacramento Cancer Center | Stage IVA Prostate Cancer AJCC v8, Advanced Esophageal Adenocarcinoma, Advanced Gastric Adenocarcinoma | 9 |
| Sutter Institute for Medical Research | Acute Ischemic Stroke, Breast Cancer, Carcinoma, Non-Small-Cell Lung | 9 |
| University of California, Davis Medical Center | Abdomen Injury, Abdomen, Acute, Abdominal Injury | 9 |
| Retinal Consultants Medical Group | Diabetic Macular Edema, Geographic Atrophy, Age - Related Macular Degeneration (AMD) | 7 |
| University of California, Davis - Dermatology Department | Scarring, Actinic Keratoses, Psoriasis | 7 |
| UC Davis MIND Institute | ADHD, Attention Deficit Hyperactivity Disorder, Down Syndrome | 7 |
| University of California - Davis | AMD, Alzheimer Disease, Huntington's Disease | 7 |
| UC Davis EXPLORER Molecular Imaging Center | Breast Cancer, Cardiovascular Disease, Chronic Low-back Pain (cLBP) | 6 |
| University of California Davis Health System | Anxiety, COVID-19, Cardiovascular Diseases | 6 |
| Integrative Skin Science and Research | Atopic Dermatitis, Atopic, Dermatitis | 5 |
| UC Davis Children's Hospital | Abdominal Pain, Ductus Arteriosus, Patent, Gastroschisis | 5 |
Active & Upcoming Studies in Sacramento (2026)
Recruiting trials in Sacramento grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (193 active studies)
- Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial · Phase 3 · National Cancer Institute (NCI)
- Testing the Addition of Cemiplimab (REGN2810) to Chemotherapy Treatment Given Prior to Surgery in Patients With Sinonasal Squamous Cell Carcinoma · Phase 2 · National Cancer Institute (NCI)
Cardiovascular (32 active studies)
- A Prospective, Randomized Multicenter Clinical Trial of the TricValve® Transcatheter Bicaval Valve System in Subjects With Severe Tricuspid Regurgitation. · P+F Products + Features USA Inc.
- EPX-HTG for Structural Heart Procedures · EchoPixel, Inc.
Neurology & pain (30 active studies)
- Morphine or Ketamine for Analgesia · Phase 3 · Columbia University
- Examining Relationships Between Musculoskeletal Function Measurements of Movement Efficiency and Nervous System Function After Chronic Stroke · University of California, Davis
Eye & vision (24 active studies)
- A Study to Evaluate Efficacy, Safety, and Immunogenicity With ABP 938 8 mg Versus EYLEA® HD (Aflibercept) in Participants With Neovascular Age-related Macular Degeneration · Phase 3 · Amgen
- A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated · Phase 1, Phase 2 · Boehringer Ingelheim
Diabetes & metabolic (23 active studies)
- A Study of Orforglipron (LY3502970) Compared With Dulaglutide in Pediatric Participants With Type 2 Diabetes · Phase 3 · Eli Lilly and Company
- A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus on Background Insulin · Phase 3 · AstraZeneca
Mental health & behavior (10 active studies)
- Sham-Controlled Rapid-Acting Neuromodulation for Depression · University of California, Davis
- Supporting Mental Health and Reducing Care Stress in Caregivers of Persons With Cardiovascular Disease · University of California, Davis
Vaccines (4 active studies)
- A Study on the Immune Response and Safety of an Investigational Combined Measles, Mumps, Rubella and Varicella Vaccine, When Given to Healthy Children 4 to 6 Years of Age · Phase 3 · GlaxoSmithKline
- Multiparametric [18F]F-AraG Imaging in Post-Acute Sequelae of COVID-19 (PASC) · EARLY_Phase 1 · University of California, Davis
HIV / STI (3 active studies)
- T-Cell Therapy (EB103) in Adults With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma (NHL) · Phase 1, Phase 2 · Estrella Biopharma, Inc.
- Kidney Transplantation From Donors With HIV: Impact on Rejection and Long-Term Outcomes (Expanding HOPE Kidney) · Johns Hopkins University
Pediatric (3 active studies)
- MiniMed Fit Payload Wear Pediatric Study · Medtronic MiniMed, Inc.
- A Study of Nipocalimab or Intravenous Immunoglobulin (IVIG) in Pregnancies At Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT) · Phase 3 · Janssen Research & Development, LLC
Common conditions studied in Sacramento
- Breast Cancer (13 active studies)
- Heart Failure (12 active studies)
- Acute Myeloid Leukemia (10 active studies)
- Atopic Dermatitis (10 active studies)
- Prostate Cancer (8 active studies)
- Stage IV Lung Cancer AJCC v8 (7 active studies)
Leading research sponsors in Sacramento
- University of California, Davis
- National Cancer Institute (NCI)
- Alliance for Clinical Trials in Oncology
- SWOG Cancer Research Network
- NRG Oncology
Frequently asked questions
How many paid clinical trials are currently recruiting in Sacramento?
There are approximately 583 recruiting clinical trials in Sacramento, California listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Sacramento pay participants?
Most recruiting trials in Sacramento compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Sacramento?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Sacramento?
The most common conditions under active study in Sacramento include Breast Cancer (13), Heart Failure (12), Acute Myeloid Leukemia (10), Atopic Dermatitis (10), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Sacramento?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Sacramento on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Sacramento?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Sacramento?
Recruiting research sites in Sacramento include University of California Davis Comprehensive Cancer Center, UC Davis Medical Center, University of California, Davis, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Sacramento right now?
The largest active categories in Sacramento are Cancer & tumors (193), Cardiovascular (32), Neurology & pain (30). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.