Paid Clinical Trials in Sacramento, CA
As of September 2026, 583 paid clinical trials are recruiting in Sacramento, California. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Sacramento offers studies at sites including University of California Davis Comprehensive Cancer Center for conditions such as Breast Cancer, Heart Failure, Acute Myeloid Leukemia, Atopic Dermatitis. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Sacramento
Trials by drug in Sacramento
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Newly added in Sacramento
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes
Examining Relationships Between Musculoskeletal Function Measurements of Movement Efficiency and Nervous System Function After Chronic Stroke
516 clinical trials
A Study to Evaluate Efficacy, Safety, and Immunogenicity With ABP 938 8 mg Versus EYLEA® HD (Aflibercept) in Participants With Neovascular Age-related Macular Degeneration
A Phase 2b Study of the Effects of Camoteskimab in Adults With Moderate-to-Severe Atopic Dermatitis
A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).
A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)
A Phase 2/3 Study of Brepocitinib in Adults With Lichen Planopilaris
A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin
Study to Evaluate the Safety and Efficacy of Larsucosterol in Participants With Alcohol-associated Hepatitis (AH)
Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS)
A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes
A Phase 3 Trial to Compare IV BCV Versus IV CDV for Treatment of Adenovirus Infection After Allo-HCT
A Study to Learn About a Clostridioides Difficile Vaccine in People 65 Years of Age and Older
A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC Alone in Participants With Recurrent/Metastatic Head and Neck Cancer
Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)
A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)
A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract
An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1-Mediated Proteinuric Kidney Disease
A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)
A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy
Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants With Psoriasis (PRAGMATYK)
ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer
Phase IIIb Study of Ribociclib + ET in Early Breast Cancer
A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)
Study to Evaluate Efficacy and Safety of ONL1204 in Patients With GA Associated With AMD
A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)
Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD)
Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL
A Study to Evaluate Efficacy of Remibrutinib Compared to Dupilumab at Early Timepoints in Adults With Chronic Spontaneous Urticaria Inadequately Controlled by Second Generation H1-antihistamines
Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer
Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis
Phase 2 Study to Evaluate Safety and Efficacy of Cretostimogene Grenadenorepvec in High-Risk NMIBC
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
FORAGER-1: A Study of Vepugratinib (LY3866288; LOXO-435) in Participants With Cancer With a Change in a Gene Called FGFR3
A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised
A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease
Top Research Study Locations in Sacramento
Researchers run research studies in Sacramento, CA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of California Davis Comprehensive Cancer Center | Stage IV Lung Cancer AJCC v8, Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia | 93 |
| UC Davis Medical Center | Heart Failure, Intracerebral Hemorrhage, Extremity Fracture Lower | 41 |
| University of California, Davis | Duchenne Muscular Dystrophy, Amblyopia, Amyotrophic Lateral Sclerosis | 37 |
| Mercy Cancer Center - Sacramento | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | 32 |
| Sutter Medical Center Sacramento | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8 | 32 |
| Kaiser Permanente Downtown Commons | Lung Non-Small Cell Carcinoma, Stage IIIB Lung Cancer AJCC v8, Stage IV Lung Cancer AJCC v8 | 30 |
| Kaiser Permanente-South Sacramento | Breast Cancer, Lung Non-Small Cell Carcinoma, Stage IIIB Lung Cancer AJCC v8 | 29 |
| UC Davis Health | Heart Failure, Acinetobacter Baumannii-calcoaceticus Complex Infection (ABC), Acute Pain | 22 |
| University of California Davis | Adenovirus Infections, Advanced Lung Carcinoma, Breast Cancer | 17 |
| UC Davis | Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Autoimmune Encephalitis | 15 |
| University of California, Davis Comprehensive Cancer Center | Advanced Solid Tumor, Colorectal Cancer, Locally Advanced Solid Tumor | 14 |
| UC Davis Comprehensive Cancer Center | Avascular Necrosis, Carcinoma, Non-Small-Cell Lung, Colorectal Cancer | 11 |
| University of California Davis Health | Articular Cartilage Defect, Articular Cartilage Disorder of Knee, Breast Cancer | 11 |
| University of California Davis Medical Center | Bariatric Surgery Candidate, Cardiovascular Diseases, Connective Tissue Diseases | 10 |
| University of California, Davis Medical Center | Abdomen Injury, Abdomen, Acute, Abdominal Injury | 10 |
| South Sacramento Cancer Center | Stage IVA Prostate Cancer AJCC v8, Advanced Esophageal Adenocarcinoma, Advanced Gastric Adenocarcinoma | 9 |
| University of California Davis Health System | Anxiety, Aortic Arch Aneurysm, Aortic Arch Dissection | 7 |
| UC Davis MIND Institute | ADHD, Attention Deficit Hyperactivity Disorder, Down Syndrome | 7 |
| Retinal Consultants Medical Group | Geographic Atrophy, Age - Related Macular Degeneration (AMD), Age Related Macular Degeneration | 6 |
| Sutter Institute for Medical Research | Acute Ischemic Stroke, Breast Cancer, Carcinoma, Non-Small-Cell Lung | 6 |
| UC Davis EXPLORER Molecular Imaging Center | Breast Cancer, Cardiovascular Disease, Chronic Low-back Pain (cLBP) | 6 |
| University Of California - Davis | Autism Spectrum Disorder, Bipolar Disorder, Irritability Associated With Autism Spectrum Disorder | 6 |
| Kaiser Permanente Sacramento Medical Center | Atrial Fibrillation, Intracerebral Hemorrhage, Pneumonia | 5 |
| UC Davis Children's Hospital | Abdominal Pain, Ductus Arteriosus, Patent, Gastroschisis | 5 |
| University of California, Davis - Dermatology Department | Scarring, Actinic Keratoses, Psoriasis | 5 |
Active & Upcoming Studies in Sacramento (2026)
Recruiting trials in Sacramento grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (192 active studies)
- ctDNA-Informed Management of Early-Stage Rectal Cancer · Phase 2 · University of California, Davis
- Testing the Addition of Cemiplimab (REGN2810) to Chemotherapy Treatment Given Prior to Surgery in Patients With Sinonasal Squamous Cell Carcinoma · Phase 2 · National Cancer Institute (NCI)
Cardiovascular (34 active studies)
- Dopamine vs. Norepinephrine for Hypotension in Neonates With Pulmonary Hypertension (DONE) · Phase 4 · University of California, Davis
- A Prospective, Randomized Multicenter Clinical Trial of the TricValve® Transcatheter Bicaval Valve System in Subjects With Severe Tricuspid Regurgitation. · P+F Products + Features USA Inc.
Neurology & pain (31 active studies)
- Virtual Reality (VR) Audiovisual Distraction to Reduce Pain and Anxiety for Prone Pain Procedures · University of California, Davis
- Morphine or Ketamine for Analgesia · Phase 3 · Columbia University
Diabetes & metabolic (23 active studies)
- A Study of Orforglipron (LY3502970) Compared With Dulaglutide in Pediatric Participants With Type 2 Diabetes · Phase 3 · Eli Lilly and Company
- Research Study on How People With Type 2 Diabetes Tolerate Switching From Semaglutide to Cagrisema · Phase 3 · Novo Nordisk A/S
Eye & vision (20 active studies)
- A Study to Evaluate Efficacy, Safety, and Immunogenicity With ABP 938 8 mg Versus EYLEA® HD (Aflibercept) in Participants With Neovascular Age-related Macular Degeneration · Phase 3 · Amgen
- A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated · Phase 1, Phase 2 · Boehringer Ingelheim
Mental health & behavior (11 active studies)
- Sham-Controlled Rapid-Acting Neuromodulation for Depression · University of California, Davis
- Virtual Reality (VR) Audiovisual Distraction to Reduce Pain and Anxiety for Prone Pain Procedures · University of California, Davis
Vaccines (5 active studies)
- A Study on the Immune Response and Safety of an Investigational Combined Measles, Mumps, Rubella and Varicella Vaccine, When Given to Healthy Children 4 to 6 Years of Age · Phase 3 · GlaxoSmithKline
- Multiparametric [18F]F-AraG Imaging in Post-Acute Sequelae of COVID-19 (PASC) · EARLY_Phase 1 · University of California, Davis
HIV / STI (3 active studies)
- T-Cell Therapy (EB103) in Adults With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma (NHL) · Phase 1, Phase 2 · Estrella Biopharma, Inc.
- Kidney Transplantation From Donors With HIV: Impact on Rejection and Long-Term Outcomes (Expanding HOPE Kidney) · Johns Hopkins University
Pediatric (2 active studies)
- A Study of Nipocalimab or Intravenous Immunoglobulin (IVIG) in Pregnancies At Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT) · Phase 3 · Janssen Research & Development, LLC
- Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS · Phase 2, Phase 3 · Nationwide Children's Hospital
Common conditions studied in Sacramento
- Breast Cancer (14 active studies)
- Heart Failure (13 active studies)
- Acute Myeloid Leukemia (10 active studies)
- Atopic Dermatitis (9 active studies)
- Prostate Cancer (8 active studies)
- Stage IV Lung Cancer AJCC v8 (7 active studies)
Leading research sponsors in Sacramento
- University of California, Davis
- National Cancer Institute (NCI)
- NRG Oncology
- SWOG Cancer Research Network
- Alliance for Clinical Trials in Oncology
Frequently asked questions
How many paid clinical trials are currently recruiting in Sacramento?
There are approximately 583 recruiting clinical trials in Sacramento, California listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Sacramento pay participants?
Most recruiting trials in Sacramento compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Sacramento?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Sacramento?
The most common conditions under active study in Sacramento include Breast Cancer (14), Heart Failure (13), Acute Myeloid Leukemia (10), Atopic Dermatitis (9), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Sacramento?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Sacramento on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Sacramento?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Sacramento?
Recruiting research sites in Sacramento include University of California Davis Comprehensive Cancer Center, UC Davis Medical Center, University of California, Davis, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Sacramento right now?
The largest active categories in Sacramento are Cancer & tumors (192), Cardiovascular (34), Neurology & pain (31). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.