Myeloproliferative neoplasm Clinical Trials

Recruiting myeloproliferative neoplasm studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat myeloproliferative neoplasm. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting myeloproliferative neoplasm studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting myeloproliferative neoplasm trials

Within

Automated Total Marrow and Lymphoid Irradiation for Allogeneic Hematopoietic Cell Transplant

for Acute Myeloid Leukemia

1 site in Palo Alto

Sponsor: Stanford University

Sex: All·Age: 18 - 70

Code: NCT07634536·Phase 2

A Pragmatic Clinical Trial to Prevent Relapse for Myeloid Malignancies With Measurable Disease Prior to Allogeneic Transplant

for Myeloid Disorders

1 site in Milwaukee

Sponsor: Medical College of Wisconsin

Sex: All·Age: 18+

Code: NCT07572929·Phase 2

Phase I Trial of Pacritinib in Combination With Venetoclax and Azacitidine for the Treatment of Accelerated and Blast Phase Myeloproliferative Neoplasms

for Myeloproliferative Neoplasm

1 site in Buffalo

Sponsor: Roswell Park Cancer Institute

Sex: All·Age: 18+

Code: NCT07679334·Phase 1

Pacritinib With Aza for Upfront Myelodysplastic Syndrome

for Myelodysplastic Syndromes

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT07387354·Phase 1, Phase 2

Caris Chromoseq Data Collection

for Acute Myeloid Leukemia (AML)

1 site in Phoenix

Sponsor: Caris Science, Inc.

Sex: All·Age: 18+

Code: NCT07680868

Apply to this trial

Replacing Bone Marrow Diagnostics With Peripheral Blood Analysis in MPN Patients

for Myeloproliferative Neoplasm

Sponsor: Weizmann Institute of Science

Sex: All·Age: 18+

Code: NCT07648433

A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplant

for Accelerated Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive

3 sites incl. Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT07020533·Phase 1

Apply to this trial

Efficacy and Safety of Ropeginterferon Alfa 2b (P1101) for Patients With Polycythemia Vera

for Polycythemia Vera

Sponsor: PharmaEssentia

Sex: All·Age: 18 - 59

Code: NCT06290765·Phase 4

Prognostic Value of NETosis Markers for Thrombosis During Myeloproliferative Neoplasms (AVATARE)

for Myeloproliferative Neoplasm

Sponsor: University Hospital, Bordeaux

Sex: All·Age: 18+

Code: NCT07119970

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Vedolizumab Plus Post-transplant Cyclophosphamide and Short Course Tacrolimus for the Prevention of Graft Versus Host Disease in Patients Undergoing Allogeneic Hematopoietic Cell Transplantation After Reduced Intensity Conditioning

for Acute Lymphoblastic Leukemia

1 site in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18 - 80

Code: NCT06815003·Phase 2

Apply to this trial

Leukemia and Lymphoma Society (LLS) Services Impact on Outcomes and Care

for Leukemia

3 sites incl. Miami

Sponsor: University of Miami

Sex: All·Age: 18+

Code: NCT05745285

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Evaluation of the Pathobiology of CALR-mutated MPN Cells

for Myeloproliferative Neoplasm

2 sites incl. Charlotte

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06480591

Apply to this trial

Prevalence and Risk Factors of Pulmonary Hypertension in Patients with Myeloproliferative Neoplasms in Assiut University Hospital.

for Myeloproliferative Neoplasm

Sponsor: Assiut University

Sex: All·Age: 18+

Code: NCT06647706

Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With High-Risk Hematologic Diseases

for Acute Leukemia of Ambiguous Lineage

1 site in Seattle

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 6 Months - 65

Code: NCT06013423·Phase 2

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CMV-MVA Triplex Vaccination in HLA-Matched Related Stem Cell Donors for the Prevention of CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplant

for Acute Lymphoblastic Leukemia

3 sites incl. Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT06059391·Phase 2

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BeFluBu vs FluBuRux Conditioning in Haploidentical HCT

for Acute Lymphoblastic Leukemia

Sponsor: St. Petersburg State Pavlov Medical University

Sex: All·Age: 18 - 75

Code: NCT06477549·Phase 2

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Exploring the Impact of Monocytes in Myeloproliferative Neoplasia (EMYNEM)

for Myeloproliferative Neoplasm

Sponsor: University Hospital, Brest

Sex: All·Age: 18+

Code: NCT06462664

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Functional and Phenotypic Characterization of Monocytes in Myeloproliferative Syndromes

for Myeloproliferative Neoplasm

Sponsor: University Hospital, Angers

Sex: All·Age: 18+

Code: NCT06361641

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Sorafenib Relapase Prophylaxis After HCT With PTBCy Regimen

for Acute Myeloid Leukemia, in Relapse

Sponsor: St. Petersburg State Pavlov Medical University

Sex: All·Age: 18 - 75

Code: NCT06532084·Phase 2

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A Prospective Patient Reported Outcomes and Wearables Study in Myeloproliferative Neoplasms

for Myeloproliferative Neoplasm

Sponsor: Guy's and St Thomas' NHS Foundation Trust

Sex: All·Age: 18+

Code: NCT06334913

Preemptive CIML NK Cell Therapy After Hematopoietic Stem Cell Transplantation

for Acute Myeloid Leukemia

2 sites in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT06138587·Phase 1

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Impact of Epigenetic Age on Clinic-biological Presentation and Prognosis in Myeloproliferative Neoplasms Epigenetic Age in Myeloproliferative Neoplasms (EpiC)

for Myeloproliferative Neoplasm

Sponsor: University Hospital, Bordeaux

Sex: All·Age: 18+

Code: NCT06022328

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Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution

for Hematologic Malignancy

5 sites incl. Aurora

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 0 - 38

Code: NCT06131801

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Study of Venetoclax and Azacitidine in Advanced BCR-ABL Negative Myeloproliferative Neoplasms

for Myeloproliferative Neoplasm

Sponsor: University Health Network, Toronto

Sex: All·Age: 18+

Code: NCT05074355·Phase 2

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MultiOmic characteriZation of Acute Myeloid Leukemia Evolving From myelopRoliferative Neoplasm to Identify New Targeted Therapeutic Strategies

for Myeloproliferative Neoplasm

Sponsor: University Hospital, Angers

Sex: All·Age: 18+

Code: NCT06022341

Determination of the Clonality Profile in Myeloproliferative Neoplasms and Association With the Thrombotic Complications (CLOJAK)

for Myeloproliferative Neoplasm

Sponsor: University Hospital, Bordeaux

Sex: All·Age: 18+

Code: NCT05839717

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Asian Myeloproliferative Neoplasm (MPN) Registry

for Myeloproliferative Neoplasm

Sponsor: The University of Hong Kong

Sex: All·Age: 18+

Code: NCT05882773

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Identification of Factors Associated With Treatment Response in Patients With Polycythemia Vera, Essential Thrombocythemia, and Pre-myelofibrosis.

for Myeloproliferative Neoplasm

Sponsor: University Hospital, Angers

Sex: All·Age: 18+

Code: NCT05440838

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Evaluation of Optical Genome Mapping in Phi Negative Myeloproliferative Neoplasia in the Detection of Acquired Cytogenetic Abnormalities

for Myeloproliferative Neoplasm

Sponsor: Centre Hospitalier Universitaire, Amiens

Sex: All·Age: 18+

Code: NCT05714592

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Allo HSCT Using RIC and PTCy for Hematological Diseases

for Acute Myelogenous Leukemia

1 site in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: Up to 75

Code: NCT05805605·Phase 2

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Children, Adolescents and Young Adults with Myeloproliferative Neoplasia: Study of Clinico-biological Characteristics and Complications (VYP)

for Myeloproliferative Neoplasm

Sponsor: University Hospital, Brest

Sex: All·Age: 0 - 30

Code: NCT06715267

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Mechanism of Action of Interferon in the Treatment of Myeloproliferative Neoplasms

for Myeloproliferative Neoplasm

Sponsor: Institut National de la Santé Et de la Recherche Médicale, France

Sex: All·Age: 18+

Code: NCT05850273

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Olverembatinib for FGFR1-rearranged Neoplasms

for Myeloproliferative Neoplasm

Sponsor: The First Affiliated Hospital of Soochow University

Sex: All·Age: All ages

Code: NCT05521204·Phase 2

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An Optimal Dose Finding Study of N-Acetylcysteine in Patients With Myeloproliferative Neoplasms

for Myeloproliferative Neoplasm

1 site in Irvine

Sponsor: University of California, Irvine

Sex: All·Age: 18+

Code: NCT05123365·Phase 1, Phase 2

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Improving Cognitive Function in Older Adults Undergoing Stem Cell Transplant

for Leukemia

1 site in Omaha

Sponsor: University of Nebraska

Sex: All·Age: 19+

Code: NCT04898790

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Interest of CALR Allele Burden in Diagnosis and Follow-up of Patients With CALR Mutated Myeloproliferative Syndromes (CALRSUIVI)

for Myeloproliferative Neoplasm

Sponsor: University Hospital, Angers

Sex: All·Age: 18+

Code: NCT04942080

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CPX-351 and Ivosidenib for the Treatment of IDH1 Mutated Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

for Acute Myeloid Leukemia With Gene Mutations

1 site in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT04493164·Phase 2

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Sequential and Personalized PK-guided Busulfan Administration in the Frame of the Conditiong Regimen for Allo-HSCT in Patients With Malignant Hemopathies Ineligible for the Standard Myeloablative Conditioning

for Acute Leukemia

Sponsor: Institut Paoli-Calmettes

Sex: All·Age: 18 - 65

Code: NCT04451200·Phase 2

Decitabine With Ruxolitinib, Fedratinib or Pacritinib for the Treatment of Accelerated/Blast Phase Myeloproliferative Neoplasms

for Acute Myeloid Leukemia

1 site in Seattle

Sponsor: University of Washington

Sex: All·Age: 18+

Code: NCT04282187·Phase 2

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Graft Versus Host Disease-Reduction Strategies for Donor Blood Stem Cell Transplant Patients With Acute Leukemia or Myelodysplastic Syndrome (MDS)

for Acute Leukemia

3 sites incl. Tampa

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 1 - 60

Code: NCT03970096·Phase 2

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A Phase 1 Trial of CIML NK Cell Infusion for Myeloid Disease Relapse After Hematopoietic Cell Transplantation

for Acute Myeloid Leukemia

2 sites in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 12+

Code: NCT04024761·Phase 1

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Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant

for Acute Biphenotypic Leukemia

9 sites incl. Los Angeles

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 6 Months - 26·Accepts healthy volunteers

Code: NCT03779854·Phase 2

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Edetate Calcium Disodium or Succimer in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome Undergoing Chemotherapy

for Acute Myeloid Leukemia

1 site in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 1+

Code: NCT03630991·Phase 1

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Dexrazoxane Hydrochloride in Preventing Heart-Related Side Effects of Chemotherapy in Participants With Blood Cancers

for Acute Myeloid Leukemia

1 site in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 12+

Code: NCT03589729·Phase 2

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Ivosidenib and Venetoclax With or Without Azacitidine in Treating Patients With IDH1 Mutated Hematologic Malignancies

for Acute Myeloid Leukemia

4 sites incl. Boston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT03471260·Phase 1, Phase 2

Apply to this trial

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

for Cancer, Metastatic

67 sites incl. Birmingham

Sponsor: Massive Bio, Inc.

Sex: All·Age: All ages

Code: NCT03452774

Apply to this trial

Project: Every Child for Younger Patients With Cancer

for Adrenal Gland Pheochromocytoma

233 sites incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 25

Code: NCT02402244

Apply to this trial

Myeloproliferative neoplasm clinical trials — common questions

Are myeloproliferative neoplasm clinical trials free to join?

Yes. Participating in a myeloproliferative neoplasm clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a myeloproliferative neoplasm clinical trial?

Each myeloproliferative neoplasm study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a myeloproliferative neoplasm trial near me?

Use the location controls above. We'll show recruiting myeloproliferative neoplasm trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many myeloproliferative neoplasm trials are recruiting right now?

We're currently tracking roughly 25 recruiting myeloproliferative neoplasm trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Myeloproliferative neoplasm trials by city

Boston, MA Duarte, CA Birmingham, AL Seattle, WA Aurora, CO Irvine, CA Los Angeles, CA Miami, FL Milwaukee, WI Omaha, NE Palo Alto, CA Tampa, FL

Related specialties

Oncology Blood cancer