Paid Clinical Trials in Bethesda, MD
As of June 2026, 933 paid clinical trials are recruiting in Bethesda, Maryland. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Bethesda offers studies at sites including National Institutes of Health Clinical Center for conditions such as Healthy Volunteers, Prostate Cancer, Breast Cancer, Healthy Volunteer. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Bethesda
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·Clear filters·↓ Download CSVAbout research studies in Bethesda
Bethesda has approximately 933 recruiting research studies across a wide range of therapeutic areas. Maryland hosts Johns Hopkins Medicine and the NIH Clinical Center in Bethesda, giving participants access to some of the most advanced early-phase research in the country.
Top Research Study Locations in Bethesda
Researchers run research studies in Bethesda, MD at 50 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| National Institutes of Health Clinical Center | Healthy Volunteers, Healthy Volunteer, Obesity | 661 |
| Walter Reed National Military Medical Center | Acute Myeloid Leukemia, Malignant Solid Neoplasm, Acute Myeloid Leukemia Post Cytotoxic Therapy | 75 |
| National Cancer Institute Developmental Therapeutics Clinic | Metastatic Malignant Solid Neoplasm, Advanced Malignant Solid Neoplasm, Unresectable Malignant Solid Neoplasm | 12 |
| Suburban Hospital | Asthma, Atherosclerosis, Atrial Fibrillation | 10 |
| Mid-Atlantic Epilepsy and Sleep Center | Developmental and Epileptic Encephalopathy, Dravet Syndrome, Focal Epilepsy | 9 |
| National Institutes of Health | Abdominal Neoplasm, Advanced Solid Tumors, Anaplastic Astrocytoma | 8 |
| National Cancer Institute | Non Small Cell Lung Cancer, Prostate Cancer, Advanced Solid Tumor | 7 |
| National Institute of Health | Cervical Cancer, Chronic Lymphocytic Leukemia (CLL), Diffuse Large B Cell Lymphoma (DLBCL) | 7 |
| American Oncology Partners of Maryland, PA | Chronic Lymphocytic Leukemia, Immune Thrombocytopenic Purpura (ITP), Leukemia, B-cell | 5 |
| The Center for Cancer and Blood Disorders | Acute Myeloid Leukaemia (AML), Advanced Melanoma, Colorectal Cancer | 5 |
| Uniformed Services University of the Health Sciences | Alcohol Use, Arrythmia, Cardiovascular Diseases | 5 |
| NIH Clinical Center | Age-Related Macular Degeneration, COVID-19, Long Haul, Chronic Granulomatous Disease | 4 |
| National Cancer Institute (NCI) | Melanoma, Breast Cancer, Cardiofaciocutaneous Syndrome | 4 |
| American Oncology Partners of Maryland Pa | Chronic Lymphocytic Leukemia, Marginal Zone Lymphoma, B-cell Malignancy | 3 |
| American Oncology Partners, PA | Breast Neoplasms, Chronic Lymphocytic Leukemia, Multiple Myeloma Refractory | 3 |
| Maryland Oncology Hematology, P.A. | Advanced Non-Small Cell Lung Cancer, Carcinoma, Non-Small-Cell Lung, Carcinoma, Non-Small-Cell Lung (NSCLC) | 3 |
| Mid Atlantic Epilepsy and Sleep Ctr | Generalized Myasthenia Gravis, Secondary Progressive Multiple Sclerosis (SPMS) | 3 |
| NCI - Center for Cancer Research | Recurrent Hairy Cell Leukemia, Hairy Cell Leukemia, Hereditary Leiomyomatosis and Renal Cell Carcinoma | 3 |
| National Institutes of Health (NIH) | Eosinophilic Colitis, Eosinophilic Esophagitis, Eosinophilic Gastritis | 3 |
| Praxis Research Site | Focal Seizure, Epilepsy, Tonic-Clonic, Focal Onset Seizure | 3 |
| Center for Cancer and Blood Disorders-American Oncology Partners of Maryland | Follicular Lymphoma (FL), Multiple Myeloma, Chronic Lymphocytic Leukemia | 3 |
| American Oncology Partners of Maryland | Advanced Cancer, Metastatic Non Small Cell Lung Cancer | 2 |
| Center for Cancer and Blood Disorders | Multiple Myeloma, Sickle Cell Disease | 2 |
| GSK Investigational Site | Colonic Neoplasms, Multiple Myeloma, Neoplasms, Colon | 2 |
| NIH Clinical Site | Drug Induced Liver Injury, Liver Diseases | 2 |
| National Eye Institute (NEI) | Albinism, Aniridia, Best Disease | 2 |
| National Institute of Allergy and Infectious Diseases (NIAID) | Healthy Volunteer Samples, Staphylococcal Infections | 2 |
| National Institute of Environmental Health Sciences (NIEHS) | COVID-19, Puberty | 2 |
| The National Institutes of Health | Eosinophilic Esophagitis, Eosinophilic Gastritis, Gastric Motility Disorder | 2 |
| Uniformed Services University | Obstructive Sleep Apnea (OSA), Stress Disorders, Post-Traumatic | 2 |
| Walter Reed National Military Medical Center (WRNMC) | Post Traumatic Stress Disorder | 2 |
| American Oncology Partners, P.A. | Breast Cancer, Diffuse Large B-Cell Lymphoma | 2 |
| Orhopaedic Surgery Service, Walter Reed National Military Medical Center | Amputation; Traumatic, Leg, Lower, Amputation With Osseointegration | 2 |
| Akero Clinical Study Site | MASH - Metabolic Dysfunction-Associated Steatohepatitis, NASH - Nonalcoholic Steatohepatitis | 1 |
| American Gastroenterological Association | Clostridium Difficile Infection, Fecal Microbiota Transplantation, Gut Microbiome | 1 |
| American Oncology Partners PA Center for Cancer and Blood Disorders | Metastatic Hormone-sensitive Prostate Cancer | 1 |
| American Oncology Partners of Maryland PA | Endometrial Adenocarcinoma | 1 |
| American Oncology Partners, P.A. - The Center for Cancer & Blood Disorders | Cancer | 1 |
| American Oncology Partners, PA (The Center for Cancer and Blood Disorders-Bethesda) | Higher-risk Myelodysplastic Syndromes | 1 |
| American Oncology Partners, PA dba The Center for Cancer and Blood Disorders | Homeostatic Iron Regulator Gene-related Hereditary Hemochromatosis | 1 |
| Aplastic Anemia and MDS International Foundation | Paroxysmal Nocturnal Hemoglobinuria | 1 |
| Cancer Center For Blood Disorders A Division of American Oncology Partners P.A | CRC (Colorectal Cancer) | 1 |
| Capitol Surgical Center | Lumbar Spinal Stenosis | 1 |
| Child Trends | Health Behavior, Health Care Utilization, Sexually Transmitted Infections | 1 |
| Clearway Pain Solutions - Bethesda | Lumbar Spinal Stenosis | 1 |
| District Surg Ctr | Lumbar Spinal Stenosis | 1 |
| Ep0162 50488 | Stereotypical Prolonged Seizures | 1 |
| Evidera | Multiple Sclerosis | 1 |
| Evidera INC. | Multiple Sclerosis | 1 |
| GC2202 Study | B-cell Chronic Lymphocytic Leukemia, Bacterial Infections, Hypogammaglobulinemia | 1 |
Active & Upcoming Studies in Bethesda (2026)
Recruiting trials in Bethesda grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (255 active studies)
- Collection of CSF Samples From Participants With Metastatic Triple Negative Breast Cancer (TNBC) and HER2+ Breast Cancer With no Prior History Nor Active Radiographically Detectable Brain Metastases · National Cancer Institute (NCI)
- A Study to Evaluate Next-Generation Sequencing (NGS) Testing and Monitoring of B-cell Recovery to Guide Management Following Chimeric Antigen Receptor T-cell (CART) Induced Remission in Children and Young Adults With B Lineage Acute Lymphoblastic Leu... · National Cancer Institute (NCI)
Neurology & pain (60 active studies)
- Longitudinal Natural History Protocol for PRKN- and PINK1-Linked PD · National Institute of Neurological Disorders and Stroke (NINDS)
- Periganglionic Resiniferatoxin for the Treatment of Intractable Pain Due to Cancer-induced Bone Pain · Phase 1, Phase 2 · National Institute of Neurological Disorders and Stroke (NINDS)
Diabetes & metabolic (26 active studies)
- Trial of the Combination of Alpha-Lipoic Acid and Mirabegron in Women and in Men With Obesity · Phase 2 · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- Effects of Meal Macronutrients on Postprandial Lipids · Phase 2 · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Vaccines (22 active studies)
- BPL-1357 Against H1N1 Influenza Virus Challenge · Phase 2 · National Institute of Allergy and Infectious Diseases (NIAID)
- Longitudinal Deep Phenotyping of Central Mechanisms in Dysosmia: A Pilot Study Using Electrobulbogram (EBG), Functional MRI (fMRI), and Diffusion-Weighted Imaging (DWI) · National Institute on Deafness and Other Communication Disorders (NIDCD)
Mental health & behavior (19 active studies)
- Longitudinal Deep Phenotyping of Central Mechanisms in Dysosmia: A Pilot Study Using Electrobulbogram (EBG), Functional MRI (fMRI), and Diffusion-Weighted Imaging (DWI) · National Institute on Deafness and Other Communication Disorders (NIDCD)
- INSIGHT: Insomnia, Nightmares, and Sympathetic Hyperactivity Intervention · Uniformed Services University of the Health Sciences
Cardiovascular (19 active studies)
- NHLBI-Emory Advanced Cardiac CT Reconstruction · National Heart, Lung, and Blood Institute (NHLBI)
- Fibrotic Disease Activity in Cardiopulmonary Disorders Using 18F-Fibroblast Activation Protein Inhibitor (18F-FAPI-74) PET/CT Imaging · Phase 3 · National Heart, Lung, and Blood Institute (NHLBI)
HIV / STI (17 active studies)
- Immunologic and Virologic Parameters During Analytical Treatment Interruption Following Combination bNAb Therapy During Suppressive ART · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
- VIR-2218 and Peginterferon Alfa-2a for Chronic Hepatitis B · Phase 2 · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Pediatric (10 active studies)
- NCI Childhood Cancer Data Initiative (CCDI) Led Pediatric, Adolescent, and Young Adult Rare Cancer Registry for Very Rare Solid Tumors · National Cancer Institute (NCI)
- A Repository to Study Host-Microbiome Interactions in Health and Disease · National Institute of Allergy and Infectious Diseases (NIAID)
Eye & vision (5 active studies)
- Phase 4 Study: Long-term Safety and Efficacy of NT-501 in MacTel Type 2, Including Sham Procedure Participants · Phase 4 · Neurotech Pharmaceuticals
- Stargardt-like Macular Dystrophy (STDG3) Secondary to Mutations in ELOVL4 · National Eye Institute (NEI)
Common conditions studied in Bethesda
- Healthy Volunteers (22 active studies). Healthy-volunteer studies examine how new drugs behave in the body, helping researchers understand safety and dosing before later-phase trials.
- Prostate Cancer (21 active studies). Prostate cancer studies test next-generation hormone therapies, PARP inhibitors, and radioligand treatments for both localized and advanced disease.
- Breast Cancer (19 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Healthy Volunteer (17 active studies). Healthy-volunteer studies examine how new drugs behave in the body, helping researchers understand safety and dosing before later-phase trials.
- Obesity (16 active studies). Obesity trials evaluate GLP-1 and GIP receptor agonists, novel metabolic drugs, and combined lifestyle interventions for sustainable weight loss.
- Neoplasms (13 active studies). Recruiting Neoplasms studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Bethesda
- National Cancer Institute (NCI)
- National Institute of Allergy and Infectious Diseases (NIAID)
- National Heart, Lung, and Blood Institute (NHLBI)
- National Institute of Neurological Disorders and Stroke (NINDS)
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Local regulations and guidelines
Clinical trials in Maryland are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Maryland research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Bethesda. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Bethesda
Hipa.ai aggregates every recruiting study in Bethesda from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Bethesda?
There are approximately 933 recruiting clinical trials in Bethesda, Maryland listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Bethesda pay participants?
Most recruiting trials in Bethesda compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Bethesda?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Bethesda?
The most common conditions under active study in Bethesda include Healthy Volunteers (22), Prostate Cancer (21), Breast Cancer (19), Healthy Volunteer (17), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Bethesda?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Bethesda on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Bethesda?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Bethesda?
Recruiting research sites in Bethesda include National Institutes of Health Clinical Center, Walter Reed National Military Medical Center, National Cancer Institute Developmental Therapeutics Clinic, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Bethesda right now?
The largest active categories in Bethesda are Cancer & tumors (255), Neurology & pain (60), Diabetes & metabolic (26). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.