Brain disorders Clinical Trials in Bethesda, MD
As of August 2026, 33 paid clinical trials are recruiting for Brain disorders in Bethesda, Maryland. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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33 clinical trials for Brain disorders
·Clear filters·Investigate Efficacy and Safety of Carisbamate as Adjunctive Treatment for Seizures Associated With LGS in Children and Adults
Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Focal Seizures FOCUS-1
A Study on the Safety of Ozanimod Exposure in Pregnant Women and Their Offspring
Clinical Trial Comparing the Efficacy of Two Teletherapy Programs at Improving Psychological Health in People With Brain Injury
PREVENT ALL ALS Study
PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI)
ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)
CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms
Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO
Surgery as a Treatment for Medically Intractable Epilepsy
Natural History Protocol for Movement Disorders
Noninvasive Pre-surgical Evaluation of Patients With Focal Epilepsy and Establishment of a Normative Imaging Database
Deep Brain Stimulation Therapy in Movement Disorders
The Beneficial Effects of Naps on Motor Learning
PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease
Comprehensive Multimodal Analysis of Neuroimmunological Diseases of the Central Nervous System
Investigating Complex Neurodegenerative Disorders Related to Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
Magnetic Resonance Imaging (MRI) to Evaluate Activity of Multiple Sclerosis (MS)
Deep Brain Stimulation Surgery for Movement Disorders
Screening for Social Determinants of Health (SDOH) and Cognitive Function in Individuals With History of Stroke
Investigation of Blood-Brain-Barrier Breakdown Using Manganese Magnetic Resonance Imaging in Drug-Resistant Epilepsy
Effect of Corticosteroids on Inflammation at the Edge of Acute Multiple Sclerosis Plaques
Targeting Residual Activity By Precision, Biomarker-Guided Combination Therapies of Multiple Sclerosis (TRAP-MS)
Influence of Brain Oscillation-Dependent TMS on Motor Function
Tumor Related Epilepsy
MEHMO Natural History and Biomarkers
Pathological Basis of MRI Signal Changes in Multiple Sclerosis
Central Nervous System Uptake of Anti-CD8+ T Cell Minibodies in Multiple Sclerosis and Progressive Multifocal Leukoencephalopathy
Investigating Epilepsy: Screening and Evaluation
Genes and Environment in Multiple Sclerosis
Efficacy of Xeomin for Migraines in Patients With Traumatic Brain Injuries vs. Anomalous Health Incidents
Cognitive and Vascular Functioning Following TBI
Top Research Study Locations in Bethesda
Researchers run research studies in Bethesda, MD at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| National Institutes of Health Clinical Center | Healthy Volunteers, Healthy Volunteer, Prostate Cancer | 651 |
| Walter Reed National Military Medical Center | Acute Myeloid Leukemia, Malignant Solid Neoplasm, Amputation | 66 |
| National Cancer Institute Developmental Therapeutics Clinic | Metastatic Malignant Solid Neoplasm, Advanced Malignant Solid Neoplasm, Unresectable Malignant Solid Neoplasm | 11 |
| National Institutes of Health | Abdominal Neoplasm, Advanced Solid Tumors, Anaplastic Astrocytoma | 8 |
| Mid-Atlantic Epilepsy and Sleep Center | Focal Epilepsy, Epilepsy, Focal Onset Seizures | 6 |
| National Institute of Health | Cervical Cancer, Chronic Lymphocytic Leukemia (CLL), Diffuse Large B Cell Lymphoma (DLBCL) | 6 |
| NIH Clinical Center | Age-Related Macular Degeneration, COVID-19, Long Haul, Chronic Granulomatous Disease | 5 |
| National Cancer Institute | Advanced Solid Tumor, Advanced or Metastatic Solid Tumor Malignancies, Cutaneous Squamous Cell Carcinoma | 5 |
| The Center for Cancer and Blood Disorders | Acute Myeloid Leukaemia (AML), Advanced Melanoma, Colorectal Cancer | 5 |
| Uniformed Services University of the Health Sciences | Alcohol Use, Arrythmia, Cardiovascular Diseases | 5 |
| National Cancer Institute (NCI) | Melanoma, Breast Cancer, Cardiofaciocutaneous Syndrome | 4 |
| American Oncology Partners of Maryland, PA | Chronic Lymphocytic Leukemia, Immune Thrombocytopenic Purpura (ITP), Leukemia, B-cell | 3 |
| American Oncology Partners, PA | Breast Neoplasms, Chronic Lymphocytic Leukemia, Multiple Myeloma Refractory | 3 |
| Maryland Oncology Hematology, P.A. | Advanced Non-Small Cell Lung Cancer, Carcinoma, Non-Small-Cell Lung, Carcinoma, Non-Small-Cell Lung (NSCLC) | 3 |
| NCI - Center for Cancer Research | Recurrent Hairy Cell Leukemia, Hairy Cell Leukemia, Hereditary Leiomyomatosis and Renal Cell Carcinoma | 3 |
| National Institutes of Health (NIH) | Eosinophilic Colitis, Eosinophilic Esophagitis, Eosinophilic Gastritis | 3 |
| Suburban Hospital | Biochemically Recurrent Prostate Carcinoma, Malignant Neoplasm, Metastatic Prostate Carcinoma | 3 |
| Center for Cancer and Blood Disorders | Multiple Myeloma, Sickle Cell Disease, CLL | 3 |
| American Oncology Partners of Maryland Pa | Chronic Lymphocytic Leukemia, B-cell Malignancy, CLL | 2 |
| American Oncology Partners, PA dba The Center for Cancer and Blood Disorders | Homeostatic Iron Regulator Gene-related Hereditary Hemochromatosis, Secondary Immune Deficiency | 2 |
| GSK Investigational Site | Colonic Neoplasms, Multiple Myeloma, Neoplasms, Colon | 2 |
| Mid Atlantic Epilepsy and Sleep Ctr | Generalized Myasthenia Gravis, Secondary Progressive Multiple Sclerosis (SPMS) | 2 |
| Mid-Atlantic Epilepsy and Sleep Center - Bethesda | Developmental and Epileptic Encephalopathy, Dravet Syndrome | 2 |
| NIH Clinical Site | Drug Induced Liver Injury, Liver Diseases | 2 |
| National Eye Institute (NEI) | Albinism, Aniridia, Best Disease | 2 |
Active & Upcoming Studies in Bethesda (2026)
Recruiting trials in Bethesda grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (235 active studies)
- A Multicenter Study to Evaluate Next-Generation Sequencing (NGS) Testing and Monitoring of B-Cell Recovery to Guide Management Following Chimeric Antigen Receptor T-cell (CART) Induced Remission in Children and Young Adults With B Lineage Acute Lymph... · National Cancer Institute (NCI)
- A UGT1A1 Genotype-Directed Study of Belinostat Pharmacokinetics and Toxicity · Phase 2 · National Cancer Institute (NCI)
Neurology & pain (60 active studies)
- Longitudinal Natural History Protocol for PRKN- and PINK1-Linked PD · National Institute of Neurological Disorders and Stroke (NINDS)
- Massage, Sleep , and Pain · Defense and Veterans Center for Integrative Pain Management
Diabetes & metabolic (25 active studies)
- Trial of the Combination of Alpha-Lipoic Acid and Mirabegron in Women and in Men With Obesity · Phase 2 · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- Effects of Meal Macronutrients on Postprandial Lipids · Phase 2 · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Vaccines (19 active studies)
- Longitudinal Deep Phenotyping of Central Mechanisms in Dysosmia: A Pilot Study Using Electrobulbogram (EBG), Functional MRI (fMRI), and Diffusion-Weighted Imaging (DWI) · National Institute on Deafness and Other Communication Disorders (NIDCD)
- BPL-1357 Against H1N1 Influenza Virus Challenge · Phase 2 · National Institute of Allergy and Infectious Diseases (NIAID)
Mental health & behavior (19 active studies)
- Longitudinal Deep Phenotyping of Central Mechanisms in Dysosmia: A Pilot Study Using Electrobulbogram (EBG), Functional MRI (fMRI), and Diffusion-Weighted Imaging (DWI) · National Institute on Deafness and Other Communication Disorders (NIDCD)
- INSIGHT: Insomnia, Nightmares, and Sympathetic Hyperactivity Intervention · Uniformed Services University of the Health Sciences
Cardiovascular (19 active studies)
- NHLBI-Emory Advanced Cardiac CT Reconstruction · National Heart, Lung, and Blood Institute (NHLBI)
- Fibrotic Disease Activity in Cardiopulmonary Disorders Using 18F-Fibroblast Activation Protein Inhibitor (18F-FAPI-74) PET/CT Imaging · Phase 3 · National Heart, Lung, and Blood Institute (NHLBI)
HIV / STI (17 active studies)
- Immunologic and Virologic Parameters During Analytical Treatment Interruption Following Combination bNAb Therapy During Suppressive ART · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
- VIR-2218 and Peginterferon Alfa-2a for Chronic Hepatitis B · Phase 2 · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Pediatric (10 active studies)
- NCI Childhood Cancer Data Initiative (CCDI) Led Pediatric, Adolescent, and Young Adult Rare Cancer Registry for Very Rare Solid Tumors · National Cancer Institute (NCI)
- A Repository to Study Host-Microbiome Interactions in Health and Disease · National Institute of Allergy and Infectious Diseases (NIAID)
Eye & vision (5 active studies)
- Phase 4 Study: Long-term Safety and Efficacy of NT-501 in MacTel Type 2, Including Sham Procedure Participants · Phase 4 · Neurotech Pharmaceuticals
- Stargardt-like Macular Dystrophy (STDG3) Secondary to Mutations in ELOVL4 · National Eye Institute (NEI)
Common conditions studied in Bethesda
- Healthy Volunteers (24 active studies)
- Prostate Cancer (20 active studies)
- Breast Cancer (19 active studies)
- Healthy Volunteer (17 active studies)
- Obesity (15 active studies)
- Neoplasms (14 active studies)
Leading research sponsors in Bethesda
- National Cancer Institute (NCI)
- National Institute of Allergy and Infectious Diseases (NIAID)
- National Heart, Lung, and Blood Institute (NHLBI)
- National Institute of Neurological Disorders and Stroke (NINDS)
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Frequently asked questions
How many paid clinical trials are currently recruiting in Bethesda?
There are approximately 893 recruiting clinical trials in Bethesda, Maryland listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Bethesda pay participants?
Most recruiting trials in Bethesda compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Bethesda?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Bethesda?
The most common conditions under active study in Bethesda include Healthy Volunteers (24), Prostate Cancer (20), Breast Cancer (19), Healthy Volunteer (17), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Bethesda?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Bethesda on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Bethesda?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Bethesda?
Recruiting research sites in Bethesda include National Institutes of Health Clinical Center, Walter Reed National Military Medical Center, National Cancer Institute Developmental Therapeutics Clinic, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Bethesda right now?
The largest active categories in Bethesda are Cancer & tumors (235), Neurology & pain (60), Diabetes & metabolic (25). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.