Paid Clinical Trials in Bluffton, SC
As of August 2026, 30 paid clinical trials are recruiting in Bluffton, South Carolina. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Bluffton offers studies at sites including Saint Joseph's/Candler - Bluffton Campus for conditions such as Anatomic Stage II Breast Cancer AJCC v8, Stage IV Lung Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Bluffton
Trials by drug in Bluffton
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Newly added in Bluffton
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
30 clinical trials
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)
Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS)
Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD)
A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)
Single Intravitreal (IVT) Injection of 4D-150 in Patients With Macular Neovascularization Secondary to Age-Related Macular Degeneration
Real-world Experience Using Nemolizumab in the Treatment of Moderate-to-Severe Atopic Dermatitis in Adolescents & Adults
A Phase 3B Study to Evaluate Bone Mineral Density With Long-Term Use of Relugolix Combination Tablet in Women With Uterine Fibroids or Endometriosis
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab
Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer
A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer
Mobile Health for Adherence in Breast Cancer Patients
The CDK4/6 Inhibitor Dosing Knowledge (CDK) Study
Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer
Cost Communication and Financial Navigation in Cancer Patients (COSTCOM)
Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer
Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)
TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer
Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors
De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)
Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)
S1703 Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Receptor Positive Her2 Negative Metastatic Breast Cancer
Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics
Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study
Prospective Non-Interventional Study Comparing Osimertinib +/- Chemotherapy for EGFR-Mutated NSCLC Patients
Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer
LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia
Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma
Top Research Study Locations in Bluffton
Researchers run research studies in Bluffton, SC at 13 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Saint Joseph's/Candler - Bluffton Campus | Anatomic Stage II Breast Cancer AJCC v8, Stage IV Lung Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | 19 |
| Charleston Neuroscience Institute - Bluffton | Age-Related Macular Degeneration, Choroidal Neovascularization, Macular Degeneration | 2 |
| Adverum Clinical | Neovascular Age-Related Macular Degeneration (nAMD), Wet AMD | 1 |
| Bluffton | Endometriosis, Uterine Fibroids | 1 |
| Charleston Neuroscience Institute, LLC | Neovascular Age-Related Macular Degeneration (nAMD) | 1 |
| Galderma Investigational | Atopic Dermatitis | 1 |
| Lewis Cancer and Research Pavilion at Saint Joseph's/Candler: SJC Bluffton Campus | Epidermal Growth Factor Receptor Gene Mutation, Non Small Cell Lung Cancer, Stage III Lung Cancer | 1 |
| PanAmerican Clinical Research - Bluffton | Type 2 Diabetes | 1 |
| SC Cancer Specialists at St. Joseph's/Candler Bluffton | Advanced Solid Tumors, Lymphoma, Non-Hodgkin, Multiple Myeloma | 1 |
| Saint Joseph's Candler Health System | Non Small Cell Lung Cancer | 1 |
| St. Joseph's Candler Bluffton Campus | Metastatic Breast Cancer | 1 |
| St. Joseph's/Candler Smith | Advanced Solid Tumors, Lymphoma, Non-Hodgkin, Multiple Myeloma | 1 |
| Summit Cancer Care at St. Josph's/Candler Bluffton | Advanced Solid Tumors, Lymphoma, Non-Hodgkin, Multiple Myeloma | 1 |
Active & Upcoming Studies in Bluffton (2026)
Recruiting trials in Bluffton grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (21 active studies)
- Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study · Phase 2 · SWOG Cancer Research Network
- Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial) · Phase 2, Phase 3 · SWOG Cancer Research Network
Eye & vision (4 active studies)
- A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002) · Phase 2, Phase 3 · EyeBiotech Ltd.
- Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS) · Phase 3 · Adverum Biotechnologies, Inc.
Diabetes & metabolic (1 active study)
- A Study to Test Whether Survodutide Helps People With Type 2 Diabetes Control Their Blood Sugar · Phase 3 · Boehringer Ingelheim
Common conditions studied in Bluffton
- Anatomic Stage II Breast Cancer AJCC v8 (3 active studies)
- Stage IV Lung Cancer AJCC v8 (3 active studies)
- Anatomic Stage IIIA Breast Cancer AJCC v8 (2 active studies)
- Anatomic Stage IIIB Breast Cancer AJCC v8 (2 active studies)
- Anatomic Stage IV Breast Cancer AJCC v8 (2 active studies)
- Breast Carcinoma (2 active studies)
Leading research sponsors in Bluffton
- SWOG Cancer Research Network
- NRG Oncology
- National Cancer Institute (NCI)
- American Society of Clinical Oncology
- ECOG-ACRIN Cancer Research Group
Frequently asked questions
How many paid clinical trials are currently recruiting in Bluffton?
There are approximately 30 recruiting clinical trials in Bluffton, South Carolina listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Bluffton pay participants?
Most recruiting trials in Bluffton compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Bluffton?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Bluffton?
The most common conditions under active study in Bluffton include Anatomic Stage II Breast Cancer AJCC v8 (3), Stage IV Lung Cancer AJCC v8 (3), Anatomic Stage IIIA Breast Cancer AJCC v8 (2), Anatomic Stage IIIB Breast Cancer AJCC v8 (2), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Bluffton?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Bluffton on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Bluffton?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Bluffton?
Recruiting research sites in Bluffton include Saint Joseph's/Candler - Bluffton Campus, Charleston Neuroscience Institute - Bluffton, Adverum Clinical, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Bluffton right now?
The largest active categories in Bluffton are Cancer & tumors (21), Eye & vision (4), Diabetes & metabolic (1). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.