Paid Clinical Trials in North Charleston, SC
As of July 2026, 54 paid clinical trials are recruiting in North Charleston, South Carolina. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
North Charleston offers studies at sites including Coastal Carolina Research Center for conditions such as Obesity, Overweight, Atopic Dermatitis, Atrial Fibrillation. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in North Charleston
Trials by drug in North Charleston
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Newly added in North Charleston
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
A Research Study Comparing How Well Different Doses of the Medicine UBT251 Lower Blood Sugar in People With Type 2 Diabetes
A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes Mellitus by Comparing it With Semaglutide, a Medicine Already Used to Treat Type 2 Diabetes Mellitus
A Study to Evaluate the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine
Efficacy of PP-01 in Mitigating Cannabis Withdrawal Symptoms in Adults With Cannabis Use Disorder
48 clinical trials
A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD)
A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)
A Study to See How Safe and Effective Alirocumab is When Given Weekly to Adult Participants Who Have Hypercholesterolemia
A 26-Wk Study to Assess Safety & Efficacy of Tenapanor for T/t of Chronic Idiopathic Constipation in Adults
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes
A Study of CX11 Tablets in Patients With Type 2 Diabetes Mellitus
Evaluation of Efficacy and Safety of Suzetrigine (SUZ) for Pain Associated With Diabetic Peripheral Neuropathy
A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight
A Study to Investigate Safety and Efficacy of Tapinarof Cream, 1% in Participants Ages 3 Months to < 24 Months With Atopic Dermatitis
Efficacy and Safety of Ribupatide Administered Once Weekly Compared With Semaglutide and Placebo in Participants Living With Obesity Who Do Not Have Diabetes
A Study of Dotinurad Versus Allopurinol in Participants With Gout
A Study of Dotinurad Versus Allopurinol in Tophaceous Gout
A Study to Evaluate Efficacy of Remibrutinib Compared to Dupilumab at Early Timepoints in Adults With Chronic Spontaneous Urticaria Inadequately Controlled by Second Generation H1-antihistamines
The CONFORM Pivotal Trial
A Study to Evaluate the Long-Term Safety of Astegolimab in Participants With Chronic Obstructive Pulmonary Disease (COPD)
Efficacy and Safety of TYRA-300 in Participants With FGFR3 Altered Low Grade, Intermediate Risk Non-Muscle Invasive Bladder Cancer
A Phase 3 Single-arm Study of UGN-104 for the Treatment of Low-grade Upper Tract Urothelial Cancer
Study of Erdafitinib Intravesical Delivery System for Localized Bladder Cancer
A Study To Learn About Two Study Medicines (PF-07275315 And PF-07264660) In People Who Have Moderate To Severe Atopic Dermatitis
Phase 2 Study to Evaluate Safety and Efficacy of Cretostimogene Grenadenorepvec in High-Risk NMIBC
A Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia
A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants
Evaluation of SPN-812 (Viloxazine Extended-release Capsule) in Preschool-age Children With ADHD
Evaluation of the Tolerability of Cagrilintide in Participants Not Tolerating GLP-1-RA Therapies Due to Gastrointestinal Adverse Events
A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
AMAZE 1: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Lose Weight
A Study of Brenipatide in Adults Who Quit Smoking Cigarettes and Want to Avoid Relapse
A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction
A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction
Sacral Neuromodulation for Male Overactive Bladder (MOAB)
Efficacy and Safety of Subcutaneous Dupilumab for the Treatment of Adult Participants With Chronic Pruritus of Unknown Origin (CPUO) (LIBERTY-CPUO-CHIC)
A Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis or Crohn's Disease
Efficacy and Safety of 186 mcg of OPN-375 Nasal Spray Twice a Day (BID) in Adolescents With Chronic Rhinosinusitis Without Nasal Polyps
A Study of STM-416 Administered to Patients Undergoing TURBT for Recurrent Bladder Cancer
A Long-term Extension Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia
A Phase 2A Clinical Trial to Assess the Safety and Tolerability of ERX1000 in Men and Women for the Treatment of Obesity.
A Study to Evaluate the Efficacy and Safey of PTP-001 (MOTYS™) in Knee Osteoarthritis Patients
Prospective Observational Study to Validate Circulating HPVDNA and Prognostic Genomic Biomarkers in HPV-associated OPSCC
ENV-294 for Moderate-to-Severe Asthma: A 12-Week Study in Adults
A Study of KT-621 Administered Orally to Adult Participants With Moderate to Severe Eosinophilic Asthma
Top Research Study Locations in North Charleston
Researchers run research studies in North Charleston, SC at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Coastal Carolina Research Center | Acute Migraine, Attention-Deficit/Hyperactivity Disorder, Chronic Idiopathic Constipation (CIC) | 8 |
| Coastal Carolina Research Ctr | Obesity, Overweight | 4 |
| Coastal Carolina Research Center - Main | Gout, Tophaceous Gout | 2 |
| MUSC Shawn Jenkins Children's Hospital - Cardiology | Heart Failure (Pediatric), Left Ventricular Systolic Dysfunction | 2 |
| Monroe Biomedical Research | Obesity & Overweight, Urinary Incontinence | 2 |
| North Charleston, South Carolina | Idiopathic Hypersomnia, Narcolepsy Type 1, Narcolepsy Type 2 | 2 |
| Carolina Endocrine Associates Llc | Hypothyroidism | 1 |
| Charleston ENT & Allergy | Chronic Rhinosinusitis Without Nasal Polyps | 1 |
| Charleston ENT and Allergy | Chronic Spontaneous Urticaria (CSU) | 1 |
| Coastal Carolina Res Ctr | Knee Osteoarthritis (OA), Obesity | 1 |
| Coastal Carolina Research | Major Depressive Disorder | 1 |
| Coastal Carolina Research Center - North Charleston | Healthy Volunteers, Human Metapneumovirus Immunization, Respiratory Syncytial Virus Immunization | 1 |
| Coastal Carolina Research Center, LLC | Cannabis Withdrawal | 1 |
| Coastal Carolina Research Center, LLD | Knee Osteoarthritis | 1 |
| Coastal Carolina Research Center_North Charleston | Hypercholesterolemia | 1 |
| Enveda Investigative Site | Asthma | 1 |
| HCA - Trident Medical Center | Atrial Fibrillation | 1 |
| Kailera Clinical Site | Obesity | 1 |
| Kymera Investigative Site | Eosinophilic Asthma | 1 |
| Low Country Urology Clinics | Non-Muscle Invasive Bladder Neoplasms | 1 |
| Low county Urology Clinics | Upper Urinary Tract Urothelial Carcinoma, Urothelial Carcinoma | 1 |
| Lowcountry Lung and Critical Care | Chronic Obstructive Pulmonary Disease | 1 |
| Lowcountry Orthopaedics and Sports Medicine | Degenerative Disc Disease | 1 |
| Lowcountry Urology | Non-muscle-invasive Bladder Cancer | 1 |
| Lowcountry Urology (Solaris) | High-Risk Non-Muscle-Invasive Bladder Cancer | 1 |
Active & Upcoming Studies in North Charleston (2026)
Recruiting trials in North Charleston grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Diabetes & metabolic (11 active studies)
- AMAZE 9: A Research Study Investigating How Well Zenagamtide Tablets Help People With Excess Body Weight Lose Weight · Phase 3 · Novo Nordisk A/S
- A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes Mellitus by Comparing it With Semaglutide, a Medicine Already Used to Treat Type 2 Diabetes Mellitus · Phase 3 · AstraZeneca
Cancer & tumors (5 active studies)
- A Phase 3 Single-arm Study of UGN-104 for the Treatment of Low-grade Upper Tract Urothelial Cancer · Phase 3 · UroGen Pharma Ltd.
- Sacral Neuromodulation for Male Overactive Bladder (MOAB) · Axonics, Inc.
Cardiovascular (5 active studies)
- A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction · Phase 3 · Bayer
- A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction · Phase 3 · Bayer
Neurology & pain (4 active studies)
- A Long-Term Safety Study of Elismetrep (K-304) in the Acute Treatment of Migraine · Phase 3 · Kallyope Inc.
- A Study to Evaluate the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine · Phase 3 · Kallyope Inc.
Mental health & behavior (2 active studies)
- A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD) · Phase 2 · Tonix Pharmaceuticals, Inc.
- A Study of Brenipatide in Adults Who Quit Smoking Cigarettes and Want to Avoid Relapse · Phase 2 · Eli Lilly and Company
Pediatric (2 active studies)
- A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction · Phase 3 · Bayer
- A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction · Phase 3 · Bayer
Vaccines (1 active study)
Common conditions studied in North Charleston
- Obesity (6 active studies)
- Overweight (3 active studies)
- Atopic Dermatitis (2 active studies)
- Atrial Fibrillation (2 active studies)
- Binge-Eating Disorder (2 active studies)
- Heart Failure (Pediatric) (2 active studies)
Leading research sponsors in North Charleston
- Novo Nordisk A/S
- AstraZeneca
- Axsome Therapeutics, Inc.
- Bayer
- Centessa Pharmaceuticals (UK) Limited
Frequently asked questions
How many paid clinical trials are currently recruiting in North Charleston?
There are approximately 54 recruiting clinical trials in North Charleston, South Carolina listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in North Charleston pay participants?
Most recruiting trials in North Charleston compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in North Charleston?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in North Charleston?
The most common conditions under active study in North Charleston include Obesity (6), Overweight (3), Atopic Dermatitis (2), Atrial Fibrillation (2), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in North Charleston?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in North Charleston on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in North Charleston?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in North Charleston?
Recruiting research sites in North Charleston include Coastal Carolina Research Center, Coastal Carolina Research Ctr, Coastal Carolina Research Center - Main, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in North Charleston right now?
The largest active categories in North Charleston are Diabetes & metabolic (11), Cancer & tumors (5), Cardiovascular (5). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.