Development of Optical Biometer
for Cataract and IOL Surgery
1 location in Hilton Head Island
Sponsor: Cassini Technologies
Sex: All·Age: 18+
Code: NCT07325162·Recruiting·Listed Jan 2026
Paid Clinical Trials in Hilton Head Island, SC
As of August 2026, 19 paid clinical trials are recruiting in Hilton Head Island, South Carolina. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Hilton Head Island offers studies at sites including South Carolina Cancer Specialists PC for conditions such as Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Hilton Head Island
Trials by drug in Hilton Head Island
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19 clinical trials
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
for Breast Cancer
Sites in Hilton Head Island, Bluffton +1098 more locations
Sponsor: NRG Oncology
Sex: Female·Age: 18 - 60
Code: NCT05879926·Phase 3·Recruiting·Listed May 2023
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
for Lung Non-Small Cell Carcinoma
Sites in Hilton Head Island, Bluffton +633 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT04267848·Phase 3·Recruiting·Listed Feb 2020
Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab
for Anatomic Stage II Breast Cancer AJCC v8
Sites in Hilton Head Island, Bluffton +777 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT05812807·Phase 3·Recruiting·Listed Apr 2023
Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer
for Anatomic Stage II Breast Cancer AJCC v8
Drug: Durvalumab
Sites in Hilton Head Island, Bluffton +525 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06058377·Phase 3·Recruiting·Listed Sep 2023
Mobile Health for Adherence in Breast Cancer Patients
for Anatomic Stage IV Breast Cancer AJCC v8
Sites in Hilton Head Island, Bluffton +457 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT06112613·Recruiting·Listed Nov 2023
The CDK4/6 Inhibitor Dosing Knowledge (CDK) Study
for Metastatic Breast Cancer
Sites in Hilton Head Island, Bluffton +71 more locations
Sponsor: American Society of Clinical Oncology
Sex: All·Age: 65+
Code: NCT06377852·Phase 3·Recruiting·Listed Apr 2024
Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer
for Previously Treated Non-Small Cell Lung Cancer
Sites in Hilton Head Island, Bluffton +948 more locations
Sponsor: SWOG Cancer Research Network
Sex: All·Age: 18+
Code: NCT03851445·Phase 2, Phase 3·Recruiting·Listed Feb 2019
Cost Communication and Financial Navigation in Cancer Patients (COSTCOM)
for Malignant Solid Neoplasm
Sites in Hilton Head Island, Bluffton +363 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: All ages·Accepts healthy volunteers
Code: NCT06295367·Recruiting·Listed Mar 2024
TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer
for Lymphoma, Non-Hodgkin
Sites in Hilton Head Island, Bluffton +144 more locations
Sponsor: American Society of Clinical Oncology
Sex: All·Age: 12+
Code: NCT02693535·Phase 2·Recruiting·Listed Feb 2016
Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors
for Malignant Solid Neoplasm
Sites in Hilton Head Island, Bluffton +586 more locations
Sponsor: SWOG Cancer Research Network
Sex: All·Age: 18+
Code: NCT04871542·Recruiting·Listed May 2021
De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)
for Stage I Breast Cancer
Sites in Hilton Head Island, Bluffton +705 more locations
Sponsor: NRG Oncology
Sex: All·Age: 50 - 70
Code: NCT04852887·Phase 3·Recruiting·Listed Apr 2021
Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)
for Recurrent Lung Non-Small Cell Carcinoma
Drug: Cemiplimab
Sites in Hilton Head Island, Bluffton +379 more locations
Sponsor: SWOG Cancer Research Network
Sex: All·Age: 18+
Code: NCT06616584·Phase 2, Phase 3·Recruiting·Listed Sep 2024
S1703 Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Receptor Positive Her2 Negative Metastatic Breast Cancer
for Anatomic Stage IV Breast Cancer AJCC v8
Sites in Hilton Head Island, Bluffton +584 more locations
Sponsor: SWOG Cancer Research Network
Sex: All·Age: 18+
Code: NCT03723928·Recruiting·Listed Oct 2018
Randomized Trial Comparing Immediate vs. Deferred Surgery for Symptomatic ERM
for Epiretinal Membrane
Sites in Hilton Head Island +46 more locations
Sponsor: Jaeb Center for Health Research
Sex: All·Age: 50+
Code: NCT05145491·Recruiting·Listed Dec 2021
Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics
for Breast Carcinoma
Sites in Hilton Head Island, Bluffton +462 more locations
Sponsor: Wake Forest University Health Sciences
Sex: All·Age: 18+
Code: NCT06418204·Recruiting·Listed May 2024
Prospective Non-Interventional Study Comparing Osimertinib +/- Chemotherapy for EGFR-Mutated NSCLC Patients
for Non Small Cell Lung Cancer
Drug: Osimertinib
Sites in Hilton Head Island, Bluffton +144 more locations
Sponsor: PrECOG, LLC.
Sex: All·Age: 18+
Code: NCT06538038·Recruiting·Listed Aug 2024
Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer
for Anatomic Stage I Breast Cancer AJCC v8
Sites in Hilton Head Island, Bluffton +913 more locations
Sponsor: SWOG Cancer Research Network
Sex: All·Age: 18+
Code: NCT05929768·Phase 3·Recruiting·Listed Jul 2023
LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia
for Advanced Colorectal Carcinoma
Sites in Hilton Head Island, Bluffton +194 more locations
Sponsor: University of Rochester
Sex: All·Age: 18+
Code: NCT06073431·Recruiting·Listed Oct 2023
Top Research Study Locations in Hilton Head Island
Researchers run research studies in Hilton Head Island, SC at 7 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| South Carolina Cancer Specialists PC | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8 | 13 |
| The Radiation Oncology Center-Hilton Head/Bluffton | Breast Carcinoma, Colorectal Carcinoma, Lung Non-Small Cell Carcinoma | 3 |
| Bishop Eye Center | Cataract and IOL Surgery | 1 |
| Hilton Head Retina Institute | Epiretinal Membrane | 1 |
| Lewis Cancer and Research Pavilion at Saint Joseph's/Candler: South Carolina Cancer Specialists | Epidermal Growth Factor Receptor Gene Mutation, Non Small Cell Lung Cancer, Stage III Lung Cancer | 1 |
| SC Cancer Specialists - Hilton Head at St. Joseph's/Candler | Metastatic Breast Cancer | 1 |
| South Carolina Cancer Specialists | Advanced Solid Tumors, Lymphoma, Non-Hodgkin, Multiple Myeloma | 1 |
Active & Upcoming Studies in Hilton Head Island (2026)
Recruiting trials in Hilton Head Island grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (15 active studies)
- Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial) · Phase 2, Phase 3 · SWOG Cancer Research Network
- Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics · Wake Forest University Health Sciences
Eye & vision (1 active study)
- Development of Optical Biometer · Cassini Technologies
Common conditions studied in Hilton Head Island
- Anatomic Stage II Breast Cancer AJCC v8 (3 active studies)
- Anatomic Stage IIIA Breast Cancer AJCC v8 (2 active studies)
- Anatomic Stage IIIB Breast Cancer AJCC v8 (2 active studies)
- Anatomic Stage IV Breast Cancer AJCC v8 (2 active studies)
- Breast Carcinoma (2 active studies)
- Early Stage Triple-Negative Breast Carcinoma (2 active studies)
Leading research sponsors in Hilton Head Island
- SWOG Cancer Research Network
- American Society of Clinical Oncology
- ECOG-ACRIN Cancer Research Group
- NRG Oncology
- National Cancer Institute (NCI)
Frequently asked questions
How many paid clinical trials are currently recruiting in Hilton Head Island?
There are approximately 19 recruiting clinical trials in Hilton Head Island, South Carolina listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Hilton Head Island pay participants?
Most recruiting trials in Hilton Head Island compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Hilton Head Island?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Hilton Head Island?
The most common conditions under active study in Hilton Head Island include Anatomic Stage II Breast Cancer AJCC v8 (3), Anatomic Stage IIIA Breast Cancer AJCC v8 (2), Anatomic Stage IIIB Breast Cancer AJCC v8 (2), Anatomic Stage IV Breast Cancer AJCC v8 (2), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Hilton Head Island?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Hilton Head Island on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Hilton Head Island?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Hilton Head Island?
Recruiting research sites in Hilton Head Island include South Carolina Cancer Specialists PC, The Radiation Oncology Center-Hilton Head/Bluffton, Bishop Eye Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Hilton Head Island right now?
The largest active categories in Hilton Head Island are Cancer & tumors (15), Eye & vision (1). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
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