Paid Clinical Trials in Charlottesville, VA
As of June 2026, 554 paid clinical trials are recruiting in Charlottesville, Virginia. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Charlottesville offers studies at sites including University of Virginia for conditions such as Acute Myeloid Leukemia, Heart Failure, Breast Cancer, Acute Respiratory Distress Syndrome. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Charlottesville
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Charlottesville has approximately 554 recruiting research studies across a wide range of therapeutic areas. Virginia hosts the University of Virginia Health System, VCU Health, and Inova Health System, running clinical trials across oncology, cardiology, and neuroscience.
Top Research Study Locations in Charlottesville
Researchers run research studies in Charlottesville, VA at 50 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Virginia | Acute Myeloid Leukemia, Cystic Fibrosis, Breast Cancer | 183 |
| University of Virginia Cancer Center | Acute Myeloid Leukemia, Stage IV Lung Cancer AJCC v8, Recurrent Endometrial Carcinoma | 92 |
| University of Virginia Health System | ARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome | 56 |
| University of Virginia Medical Center | Bone Density, Bone Strength, Coronary Artery Disease | 26 |
| University of Virginia Comprehensive Cancer Center | Cervical Cancer, AML, AML With Mutated NPM1 | 14 |
| UVA Health | Anesthesia, Anesthesia Awareness, Anesthesia Complication | 8 |
| University of Virginia | Chronic Inflammatory Demyelinating Polyneuropathy, Chronic Inflammatory Demyelinating Polyradiculoneuropathy, Polyneuropathy, Inflammatory Demyelinating, Chronic | 7 |
| Charlottesville Medical Research | Osteoarthritis, Gout, Menstrual Migraine | 6 |
| UVA Children's Hospital | Acute Respiratory Distress Syndrome, Bronchopulmonary Dysplasia, Chronic Lung Disease of Prematurity | 5 |
| UVA Medical Center | Ischemic Stroke, Atrial Fibrillation, Intracerebral Hemorrhage | 4 |
| University of Virginia (UVA) | Amyotrophic Lateral Sclerosis, Atrial Flutter Typical, Complex Congenital Heart Defect | 4 |
| University of Virginia Center for Diabetes Technology | Type 1 Diabetes, Type 1 Diabetes Mellitis, Type 2 Diabetes | 4 |
| University of Virginia Health | Colorectal Adenoma, Colorectal Cancer, Colorectal Neoplasms | 4 |
| University of Virginia School of Medicine | Acute Myeloid Leukemia (AML), Drug Resistant Epilepsy, Epilepsy | 4 |
| Charlottesville Medical Research Center, LLC | Chronic Idiopathic Constipation (CIC), Healthy Adults, Influenza | 3 |
| UVA Health University Medical Center | Cystic Fibrosis, Epilepsy, Temporal Lobe, Fracture Fixation | 3 |
| University of Virginia School of Medicine-Pediatrics | Cerebroside Lipidosis Syndrome, Fabry Disease, Gaucher Disease | 3 |
| Pediatric Research of Charlottesville, LLC | Acute Treatment of Migraine, Pediatric Migraine, Pneumococcal Infection | 3 |
| Clinical Study Site | Metastatic Colorectal Cancer (CRC), Non-Small Cell Lung Cancer | 2 |
| Clinical Trial Site | Hypophosphatasia, Transthyretin Amyloidosis With Cardiomyopathy | 2 |
| Emily Couric Clinical Cancer Center | B-Cell Non-Hodgkin Lymphoma, Clear Cell Renal Cell Carcinoma (ccRCC), Metastatic Castration-Resistant Prostate Cancer (mCRPC) | 2 |
| Pediatric Associates of Charlottesville, PLC (Private Pediatric Practice) | Acute Treatment of Migraine, Pediatric Migraine | 2 |
| Pediatric Research of Charlottesville, LLC (Regulatory Only) | Acute Treatment of Migraine, Pediatric Migraine | 2 |
| Snyder Building 480 Ray C. Hunt Drive | E-Cig Use, Idiopathic Pulmonary Fibrosis | 2 |
| UVA Comprehensive Cancer Center | Non-small Cell Lung Cancer Stage III, Ovarian Cancer, Ovarian Cancer Recurrent | 2 |
| UVA Health Systems | Clostridia Difficile Colitis, Clostridioides Difficile Infection, Clostridium Difficile Diarrhea | 2 |
| UVA School of Medicine | Tricuspid Valve Disease, Cardiovascular Diseases, Heart Failure | 2 |
| UVA University Hospital | Acute Myocardial Infarction, Acute Stress Disorder, Acute Stress Reaction | 2 |
| University Of Virginia Health System | Atrial Fibrillation, Neoplasms | 2 |
| University of Virgina | Abdominal Aortic Aneurysm, Pregnancy Outcome Trends in Low-resource Geographic Areas, Surgery | 2 |
| University of Virginia (UVA) Health - Developmental Pediatrics Clinic | Generalized Myasthenia Gravis, gMG | 2 |
| University of Virginia Clinical Research Unit | Polycystic Ovary Syndrome, Hyperandrogenism, Puberty | 2 |
| Exelixis Clinical | Extra-Pancreatic Neuroendocrine Tumor (epNET), Pancreatic Neuroendocrine Tumor (pNET), Clear Cell Renal Cell Carcinoma (ccRCC) | 2 |
| Investigational | Heart Diseases, Pericarditis, Recurrent Pericarditis | 2 |
| University of Virginia Cancer Center | Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Diffuse Large B-Cell Lymphoma | 2 |
| #1027, University of Virginia | Advanced Solid Tumor | 1 |
| Baxis | Bacterial Conjunctivitis | 1 |
| Cancer Center at the University of Virginia | Melanoma | 1 |
| Center for Research in Reproduction, University of Virginia | Hyperandrogenism, Polycystic Ovary Syndrome, Puberty | 1 |
| Charlottesville Med Research | Knee Osteoarthritis (OA), Obesity | 1 |
| Contemplative Sciences Center | Anxiety | 1 |
| Crinetics Study Site | Neuroendocrine Neoplasm, Neuroendocrine Tumors, SST2-positive Neuroendocrine Neoplasms | 1 |
| Dr. Falk Investigational Site | Eosinophilic Esophagitis | 1 |
| Dren Investigational Site | Aggressive NK Cell Leukemia, Cutaneous PTCL-NOS (CD8+ or CD56+ and Cytotoxic Marker), Cytotoxic PTCL-NOS (CD8+ or CD56+ and Cytotoxic Marker) | 1 |
| Fontaine Research Park | Knee Pain Chronic, Osteo Arthritis Knee, Surgery | 1 |
| GSK Investigational Site | Gastrointestinal Neoplasms | 1 |
| Icarus Medical Innovations | Medial Compartment Knee Osteoarthritis | 1 |
| Imbria Investigational Site | Non-obstructive Hypertrophic Cardiomyopathy | 1 |
| Investigative Site | Cancer Weight Loss | 1 |
| Investigative | Solid Tumors | 1 |
Active & Upcoming Studies in Charlottesville (2026)
Recruiting trials in Charlottesville grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (197 active studies)
- Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C Mutation · Phase 1, Phase 2 · National Cancer Institute (NCI)
- Study of GB-4362 With Enfortumab Vedotin and Pembrolizumab for Advanced Urothelial Cancer · Phase 1 · Generate Biomedicines
Cardiovascular (37 active studies)
- Pivotal Trial to Evaluate the Safety and Effectiveness of the P&F TricValve® Transcatheter Bicaval Valve System · P+F Products + Features USA Inc.
- Transition to KPL-387 Monotherapy Dosing & Administration Study · Phase 2 · Kiniksa Pharmaceuticals International, plc
Neurology & pain (36 active studies)
- A System to Help With Freezing of Gait in Parkinson's Patients · Barron Associates, Inc.
- Stereotactic MRI-guided Focused Ultrasound Mesencephalotomy · University of Virginia
Diabetes & metabolic (27 active studies)
- The Effect of Exercise and Tirzepatide on Weight and Health Outcomes (EXER-MED) · Phase 3 · University of Virginia
- A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in Children and Adolescents With Type 2 Diabetes · Phase 3 · Novo Nordisk A/S
Mental health & behavior (6 active studies)
- Sleep, Dreaming, and Virtual Reality for Mental Health · EARLY_Phase 1 · Northwestern University
- A Study of a Test for Postpartum Depression at Home · University of Virginia
Pediatric (4 active studies)
- Bone Metabolism in 12-21 Year Olds Undergoing Glucagon Like Peptide (GLP)-1 Receptor Agonist Therapy · Phase 2 · University of Virginia
- Study to Evaluate Safety and Efficacy of Different PANZYGA Dose Regimens in Pediatric Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) Patients · Phase 3 · Octapharma
Vaccines (3 active studies)
- A Study to Evaluate the Safety and Efficacy of CD388 for Prevention of Influenza · Phase 3 · Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
- Outpatient Treatment With Anti-Coronavirus Immunoglobulin · Phase 3 · University of Minnesota
HIV / STI (1 active study)
- Couples Motivational Interviewing to Reduce Drug Use and HIV Risk in Vulnerable Male Couples · Hunter College of City University of New York
Eye & vision (1 active study)
Common conditions studied in Charlottesville
- Acute Myeloid Leukemia (11 active studies). Leukemia trials evaluate targeted inhibitors, CAR-T cell therapies, and novel combinations for acute and chronic forms of the disease.
- Heart Failure (9 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
- Breast Cancer (8 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Acute Respiratory Distress Syndrome (6 active studies). Recruiting Acute Respiratory Distress Syndrome studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Atrial Fibrillation (6 active studies). Atrial fibrillation studies investigate next-generation anticoagulants, ablation technologies, and left atrial appendage closure devices.
- Endometrial Cancer (6 active studies). Recruiting Endometrial Cancer studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Charlottesville
- University of Virginia
- National Cancer Institute (NCI)
- Children's Oncology Group
- AstraZeneca
- Merck Sharp & Dohme LLC
Local regulations and guidelines
Clinical trials in Virginia are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Virginia research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Charlottesville. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Charlottesville
Hipa.ai aggregates every recruiting study in Charlottesville from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Charlottesville?
There are approximately 554 recruiting clinical trials in Charlottesville, Virginia listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Charlottesville pay participants?
Most recruiting trials in Charlottesville compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Charlottesville?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Charlottesville?
The most common conditions under active study in Charlottesville include Acute Myeloid Leukemia (11), Heart Failure (9), Breast Cancer (8), Acute Respiratory Distress Syndrome (6), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Charlottesville?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Charlottesville on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Charlottesville?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Charlottesville?
Recruiting research sites in Charlottesville include University of Virginia, University of Virginia Cancer Center, University of Virginia Health System, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Charlottesville right now?
The largest active categories in Charlottesville are Cancer & tumors (197), Cardiovascular (37), Neurology & pain (36). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.