Paid Clinical Trials in Lynchburg, VA
As of August 2026, 55 paid clinical trials are recruiting in Lynchburg, Virginia. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Lynchburg offers studies at sites including Centra Alan B Pearson Regional Cancer Center for conditions such as Breast Cancer, Lung Non-Small Cell Carcinoma, Anatomic Stage II Breast Cancer AJCC v8, Crohn's Disease. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Lynchburg
Trials by drug in Lynchburg
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Newly added in Lynchburg
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
53 clinical trials
COMO: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)
Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS)
Study of DONQ52 in Active Celiac Disease
A Study of Solbinsiran (LY3561774) in Participants With Severe Hypertriglyceridemia
Efficacy and Safety of Orforglipron in Participants With Peripheral Artery Disease
A Phase 2, Randomized, Placebo Controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL 3007 in Combination With Syfovre/Pegcetacoplan (APL-2) in Patients Diagnosed With Geographic Atrophy Secondary to Age Related Macular Degeneratio
An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease
A Study of Icotrokinra in Participants With Moderately to Severely Active Crohn's Disease
A Protocol of Icotrokinra Therapy in Adult and Adolescent Participants With Moderately to Severely Active Ulcerative Colitis
A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy
Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis
A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease
A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS)
BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT
A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)
Study to Evaluate Efficacy and Safety of ONL1204 in Patients With GA Associated With AMD
A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease
Single Intravitreal (IVT) Injection of 4D-150 in Patients With Macular Neovascularization Secondary to Age-Related Macular Degeneration
Once Daily Versus Twice Daily Budesonide Orodispersible Tablets for Induction of Remission in EoE
CCM OPEN HF Registry
EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Breast Cancer (MRD)
A Clinical Study Evaluating Licaminlimab for Dry Eye Disease
An Exploratory Efficacy and Safety Study of DFL24498 Topical Ophthalmic Solution Compared With Vehicle in Participants With Dry Eye Disease
A Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of RO7823653 in Participants With Diabetic Macular Edema (DME)
Conquer-AF Protocol for Redo Ablation Procedures in Recurrent Paroxysmal and Persistent Atrial Fibrillation Using the Sphere-9 Catheter and Affera Ablation System (Conquer-AF)
A Study to Test Whether BI 1815368 Helps People With an Eye Condition Called Diabetic Macular Edema
A Study to Optimize Subretinal Surgical Delivery and to Evaluate Safety and Activity of Opregen in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (GAlette); Adaptive Optics (AO) Retinal Imaging Substudy in Association With Study GR44251
Deep Neural Network Stratification for Use Detecting Endometriosis in Women Affected by Chronic Pelvic Pain (EndoCheck)
Evaluation of Gixam's Efficacy Predicting the Presence of Advanced and Non-advanced Colorectal Neoplasia in a FIT Negative Population
A Study to Evaluate the Efficacy and Safety of Orally Administered VX-01
Evaluation of Cataract Surgery Outcomes in Patients With Prior Laser Vision Correction Implanted With the CT LUCIA Lens
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab
mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma
ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab
Top Research Study Locations in Lynchburg
Researchers run research studies in Lynchburg, VA at 23 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Centra Alan B Pearson Regional Cancer Center | Lung Non-Small Cell Carcinoma, Anatomic Stage II Breast Cancer AJCC v8, Breast Cancer | 13 |
| Piedmont Eye Center | Diabetic Macular Edema, Geographic Atrophy, Geographic Atrophy (GA) | 13 |
| Blue Ridge Medical Research | CRC Screening, Celiac Disease, Colitis, Ulcerative | 5 |
| Centra Health, Inc. dba Stroobants Cardiovascular Center | Heart Failure, Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation | 2 |
| GSK Investigational Site | HIV Infections, Irritable Bowel Syndrome | 2 |
| Stroobants Cardiovascular Center | Peripheral Arterial Disease, Severe Hypertriglyceridemia | 2 |
| Adverum Clinical | Neovascular Age-Related Macular Degeneration (nAMD), Wet AMD | 1 |
| Alan B. Pearson Regional Cancer Center | Breast Cancer | 1 |
| Blue Ridge Ear, Nose and Throat | Osteopathic Manipulative Treatment (OMT), Otitis Media, Otitis Media Chronic | 1 |
| Blue Ridge Medical Research - Gastroenterology Associates of Central Virginia | Moderately to Severely Active Crohns Disease | 1 |
| Blue Ridge Medical Research: 8400020 | Crohn's Disease | 1 |
| Centra Health dba Stroobants Cardiovascular Center | Hypertension, Hypertension, Essential, Hypertension, Systolic | 1 |
| Centra Health, Inc.dba Stroobants Cardiovascular Center | Paroxysmal Atrial Fibrillation | 1 |
| Centra Medical Group Stroobants Cardiovascular Center | Atrial Fibrillation (AF), Paroxysmal Atrial Fibrillation (PAF), Persistent Atrial Fibrillation | 1 |
| Collaborative Healthplex | Osteopathic Manipulative Treatment (OMT), Otitis Media, Otitis Media Chronic | 1 |
| Dr. Falk Investigational Site | Eosinophilic Esophagitis | 1 |
| Gastroenterology Associates of Central Virginia | Crohn's Disease, Inflammatory Bowel Diseases | 1 |
| Piedmont Eye Center (01097) | Geographic Atrophy Secondary to Age-related Macular Degeneration | 1 |
| Piedmont Eye Center, Inc. | Dry Eye Disease (DED) | 1 |
| Surgery Center of Lynchburg | Lumbar Spinal Stenosis | 1 |
| The Education & Research Foundation | Acne | 1 |
| Vanda Investigational Site | Dry Eye | 1 |
| Womens Health Services of Central Virginia | Endometriosis | 1 |
Active & Upcoming Studies in Lynchburg (2026)
Recruiting trials in Lynchburg grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Eye & vision (15 active studies)
- An Exploratory Efficacy and Safety Study of DFL24498 Topical Ophthalmic Solution Compared With Vehicle in Participants With Dry Eye Disease · Phase 2 · Dompé Farmaceutici S.p.A
- A Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of RO7823653 in Participants With Diabetic Macular Edema (DME) · Phase 1 · Genentech, Inc.
Cancer & tumors (14 active studies)
- Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors · Phase 3 · SWOG Cancer Research Network
- ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab · Phase 3 · Alliance for Clinical Trials in Oncology
Cardiovascular (5 active studies)
- Conquer-AF Protocol for Redo Ablation Procedures in Recurrent Paroxysmal and Persistent Atrial Fibrillation Using the Sphere-9 Catheter and Affera Ablation System (Conquer-AF) · Medtronic Cardiac Ablation Solutions
- CCM OPEN HF Registry · Impulse Dynamics
HIV / STI (1 active study)
Mental health & behavior (1 active study)
- E-Mindfulness Approaches for Living After Breast Cancer · Phase 3 · NRG Oncology
Pediatric (1 active study)
Common conditions studied in Lynchburg
- Breast Cancer (3 active studies)
- Lung Non-Small Cell Carcinoma (3 active studies)
- Anatomic Stage II Breast Cancer AJCC v8 (2 active studies)
- Crohn's Disease (2 active studies)
- Diabetic Macular Edema (2 active studies)
- Dry Eye Disease (DED) (2 active studies)
Leading research sponsors in Lynchburg
- Alliance for Clinical Trials in Oncology
- Genentech, Inc.
- Janssen Research & Development, LLC
- NRG Oncology
- National Cancer Institute (NCI)
Frequently asked questions
How many paid clinical trials are currently recruiting in Lynchburg?
There are approximately 55 recruiting clinical trials in Lynchburg, Virginia listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Lynchburg pay participants?
Most recruiting trials in Lynchburg compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Lynchburg?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Lynchburg?
The most common conditions under active study in Lynchburg include Breast Cancer (3), Lung Non-Small Cell Carcinoma (3), Anatomic Stage II Breast Cancer AJCC v8 (2), Crohn's Disease (2), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Lynchburg?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Lynchburg on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Lynchburg?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Lynchburg?
Recruiting research sites in Lynchburg include Centra Alan B Pearson Regional Cancer Center, Piedmont Eye Center, Blue Ridge Medical Research, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Lynchburg right now?
The largest active categories in Lynchburg are Eye & vision (15), Cancer & tumors (14), Cardiovascular (5). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.