Paid Clinical Trials in Salem, VA
As of August 2026, 34 paid clinical trials are recruiting in Salem, Virginia. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Salem offers studies at sites including Salem VA Medical Center, Salem, VA for conditions such as Diabetic Foot Ulcer (DFU), Heart Failure, Breast Cancer, Colorectal Cancer. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Salem
Trials by drug in Salem
Filter results
34 clinical trials
Symbiotic-GU-06: A Study to Learn About PF-08634404 Alone or In Combination With Enfortumab Vedotin in Urothelial Cancer
Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer
A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Nivolumab in Combination With Chemotherapy in Participants With Previously Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (ROSETTA Gastric-204)
A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)
This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.
A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)
A Study of Disitamab Vedotin in Adults With HER2 Expressing Advanced Breast Cancer
A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS)
A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants
Surabgene Lomparvovec Administered in the Suprachoroidal Space in Adult Participants With Diabetic Retinopathy Without Center-Involved Diabetic Macular Edema
Symbiotic-Lung-04: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Extensive-Stage Small Cell Lung Cancer
A Study to Evaluate the Safety and Efficacy of Two Dose Levels of ONO-4578 With Opdivo®, in Combination With mFOLFOX6 and Bevacizumab Versus Standard of Care in Participants With Non-MSI-H/dMMR, PD-L1 Positive Advanced Colorectal Cancer
A Non-Randomized Open Label Clinical Trial Evaluating DermaBind TL
Matrion Decellularized Placental Membrane Versus Conventional Wound Management in Subjects With Diabetic Foot Ulcers
A Study to Evaluate ENERGI-F703 GEL in Diabetic Foot Ulcer
Rising Tide - Amniotic Tissue(s) Treatments for Chronic Diabetic Foot Ulcers
A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (FRUITFUL)
BMS-986489 (Atigotatug + Nivolumab) vs Durvalumab in Limited-stage Small-cell Lung Cancer (TIGOS-LS)
A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients With Heart Failure Who Are Intolerant or Not Eligible for Treatment With Steroidal Mineralocorticoid Receptor Antagonists
A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
ERP to Improve Functioning in Veterans With OCD
Study of Tucatinib and Doxil in Participants With Human Epidermal Growth Factor Receptor 2 Positive (HER2+) Metastatic Breast Cancer
The Effect of Interval Exercise on Functional Outcomes in Veterans With COPD and OSA
Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes
A Study Comparing Oral Buprenorphine and Injectable Buprenorphine for the Treatment of Opioid Use Disorder
PREVAIL Interdisciplinary Track: A Pragmatic Randomized Clinical Trial
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
Phase III Study of Rilvegostomig in Combination With Bevacizumab With or Without Tremelimumab as First-line Treatment of Hepatocellular Carcinoma
MTX-001 for the Treatment of Non-Healing Venous Stasis Ulcers
Top Research Study Locations in Salem
Researchers run research studies in Salem, VA at 20 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Salem VA Medical Center, Salem, VA | Atherosclerosis, COPD, Comorbid Post-Traumatic Stress Disorder and OCD | 4 |
| Foot and Ankle Specialists of the Mid-Atlantic | Diabetic Foot Ulcer (DFU), Chronic Foot Ulcers, Lower Extremity | 3 |
| Oncology & Hematology Associates of Southwest Virginia, Inc., DBA Blue Ridge Cancer Care | Advanced Renal Cell Carcinoma, Advanced or Metastatic Renal Cell Carcinoma, Carcinoma, Renal Cell | 3 |
| Salem VA Medical Center | Heart Failure With Mildly Reduced Ejection Fraction, Heart Failure With Preserved Ejection Fraction, Kidney Disease, Chronic | 3 |
| Blue Ridge Cancer Care | Cancer of the Prostate, Colorectal Cancer, Hormone Sensitive Prostate Cancer | 2 |
| Oncology & Hematology Associates of Southwest Virginia Inc dba Blue Ridge Cancer Care | Breast Cancer, Breast Neoplasms, Non-Small Cell Lung Cancer Metastatic | 2 |
| Salem, VA Investigative | Acute Heart Failure, Heart Failure | 2 |
| Blue Ridge Cancer Care (Oncology & Hematology Assoc of SW Virginia, Inc) | Breast Cancer | 1 |
| Blue Ridge Cancer Care (Oncology & Hematology Associates of Southwest VA) | Colon Cancer, Colorectal Cancer, Colorectal Cancer (CRC) | 1 |
| Blue Ridge Cancer Center (Oncology & Hematology Associates of Southwest VA) | Limited Stage Small Cell Lung Cancer | 1 |
| Blue Ridge Surgery Center | Lumbar Spinal Stenosis | 1 |
| Investigative | Solid Tumors | 1 |
| Lewis Gale Hospital | Lumbar Spinal Stenosis | 1 |
| Oncology & Hematology Associates of Southwest Virginia, Inc. D.B.A Blue Ridge Cancer Care | Colorectal Neoplasms | 1 |
| Oncology & Hematology Associates of Southwest Virginia, Inc.,DBA Blue Ridge Cancer Care | Advanced/Metastatic Urothelial Cancer, Urothelial Cancer, Urothelial Carcinoma | 1 |
| Oncology and Hematology Associates of Southwest Virginia, Inc. - Salem | Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma | 1 |
| Salem VA Health Care System | Chronic Pain | 1 |
| Salem Veterans Affairs Medical Center VAMC | Diabetes Mellitus, Diabetic Foot Ulcer, Foot Ulcer | 1 |
| TG Therapeutics Investigational Trial Site | Multiple Sclerosis, Relapsing Multiple Sclerosis | 1 |
| Vistar Eye Center - Salem | Diabetic Retinopathy | 1 |
Active & Upcoming Studies in Salem (2026)
Recruiting trials in Salem grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (11 active studies)
- Symbiotic-GU-06: A Study to Learn About PF-08634404 Alone or In Combination With Enfortumab Vedotin in Urothelial Cancer · Phase 1, Phase 2 · Pfizer
- Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer · Phase 1, Phase 2 · Pfizer
Cardiovascular (4 active studies)
Diabetes & metabolic (2 active studies)
- Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity · Phase 3 · Amgen
- A Study to Evaluate ENERGI-F703 GEL in Diabetic Foot Ulcer · Phase 3 · Energenesis Biomedical Co., Ltd.
Neurology & pain (2 active studies)
- A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS) · TG Therapeutics, Inc.
- PREVAIL Interdisciplinary Track: A Pragmatic Randomized Clinical Trial · Salem Veterans Affairs Medical Center
Common conditions studied in Salem
- Diabetic Foot Ulcer (DFU) (3 active studies)
- Heart Failure (3 active studies)
- Breast Cancer (2 active studies)
- Colorectal Cancer (2 active studies)
- Colorectal Neoplasms (2 active studies)
- Acute Heart Failure (1 active study)
Leading research sponsors in Salem
- Pfizer
- VA Office of Research and Development
- SCRI Development Innovations, LLC
- AbbVie
- AstraZeneca
Frequently asked questions
How many paid clinical trials are currently recruiting in Salem?
There are approximately 34 recruiting clinical trials in Salem, Virginia listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Salem pay participants?
Most recruiting trials in Salem compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Salem?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Salem?
The most common conditions under active study in Salem include Diabetic Foot Ulcer (DFU) (3), Heart Failure (3), Breast Cancer (2), Colorectal Cancer (2), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Salem?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Salem on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Salem?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Salem?
Recruiting research sites in Salem include Salem VA Medical Center, Salem, VA, Foot and Ankle Specialists of the Mid-Atlantic, Oncology & Hematology Associates of Southwest Virginia, Inc., DBA Blue Ridge Cancer Care, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Salem right now?
The largest active categories in Salem are Cancer & tumors (11), Cardiovascular (4), Diabetes & metabolic (2). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.