Oncology Clinical Trials in Chattanooga, TN
As of September 2026, 35 paid clinical trials are recruiting for Oncology in Chattanooga, Tennessee. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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35 clinical trials for Oncology
·Clear filters·Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer
This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.
Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression
A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)
A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy
Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer
A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)
A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)
A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors
A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)
A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002)
A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)
Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)
Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC
A Dose-Escalation and Expansion Study of Tacabrutideg (BGB-16673) in Participants With B-Cell Malignancies
Efficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-3076)
Study of Navtemadlin add-on to Ruxolitinib in JAK Inhibitor-Naïve Patients With Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib
A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer
Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS
Phase 3 Trial Evaluating the Safety & Efficacy of IMNN-001 Administered in Combination w/ Standard NACT & Adjuvant Chemotherapy in Newly Diagnosed Patients w/ Advanced EOC, Fallopian Tube or Primary Peritoneal Cancer
A Trial of Robotic Versus Open Hysterectomy Surgery in Cervix Cancer
Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy
Project: Every Child for Younger Patients With Cancer
Sacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBC
RSSearch Patient Registry-Long Term Study of Use of SRS/SBRT
Neoadjuvant and Adjuvant Treatment in Resectable Non-small Cell Lung Cancer
A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer (TROPION-Breast05)
A Study to Investigate the Safety and Efficacy of Belantamab for the Treatment of Multiple Myeloma When Used as Monotherapy and in Combination Treatments
A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)
Saruparib (AZD5305) Plus Camizestrant or Plus Endocrine Therapy, Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer
A Phase 3 Study to Evaluate Petosemtamab Plus Pembrolizumab vs Pembrolizumab in First-line Treatment of Head and Neck Cancer (LiGeR - HN1)
Top Research Study Locations in Chattanooga
Researchers run research studies in Chattanooga, TN at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Erlanger Health System | AChR-Ab Seropositive Generalized Myasthenia Gravis, gMG, Generalized Myasthenia Gravis | 6 |
| GSK Investigational Site | Non-alcoholic Fatty Liver Disease, Irritable Bowel Syndrome, Multiple Myeloma | 5 |
| Southeast Renal Research Institute | Diabetic Kidney Disease (DKD), End Stage Kidney Disease, Focal Segmental Glomerulosclerosis | 5 |
| T C Thompson Children's Hospital | Adrenal Gland Pheochromocytoma, B Acute Lymphoblastic Leukemia, B Lymphoblastic Lymphoma | 5 |
| Tennessee Oncology, PLLC - Chattanooga Downtown | Advanced Non-Small Cell Lung Cancer, Advanced/Metastatic Urothelial Cancer, Cancer of the Prostate | 4 |
| Tennessee Oncology, PLLC - Chattanooga Med Park II | Advanced Renal Cell Carcinoma, Advanced or Metastatic Renal Cell Carcinoma, Advanced/Metastatic Urothelial Cancer | 4 |
| Tennessee Oncology, PLLC - Chattanooga Memorial | Advanced Renal Cell Carcinoma, Advanced or Metastatic Renal Cell Carcinoma, Advanced/Metastatic Urothelial Cancer | 4 |
| Erlanger Health, Inc. | Cardiovascular Disease, Endometrioid Ovarian Cancer, Fallopian Tube Cancer | 3 |
| Tennessee Oncology | Advanced Solid Tumors, B-Cell Non-Hodgkins Lymphoma, Colorectal Cancer (CRC) | 3 |
| Tennessee Oncology - Chattanooga | Carcinoma, Non-Small-Cell Lung, Melanoma, Metastatic Castration-resistant Prostatic Neoplasms | 3 |
| Tennessee Oncology Chattanooga | Carcinoma, Non-Small-Cell Lung, Colorectal Neoplasms, Neoplasm Metastasis | 3 |
| Tennessee Oncology, PLLC - Investigational Drug Services/Supply Storage | Advanced Renal Cell Carcinoma, Advanced or Metastatic Renal Cell Carcinoma, Advanced/Metastatic Urothelial Cancer | 3 |
| University Diabetes & Endocrine Consultants | T1D, T1DM, T1DM - Type 1 Diabetes Mellitus | 3 |
| Vascular Institute of Chattanooga | Arteriovenous Fistula, Chronic Total Occlusion of Artery of the Extremities, End-stage Renal Disease | 3 |
| Clinical Trial Site | Generalized Myasthenia Gravis, High Cardiovascular Risk, High Risk Cardiovascular Disease | 2 |
| ClinSearch, LLC | Liver Fibrosis, Metabolic Dysfunction Associated Steatohepatitis, Metabolic Dysfunction Associated Steatohepatitis (MASH) | 2 |
| Erlanger Health | Epithelial Ovarian Cancer, Fallopian Tube Cancer, Heart Failure | 2 |
| Galen Medical Group - Galen Hepatology | Hepatitis, Metabolic Dysfunction-Associated Steatotic Liver Disease | 2 |
| Tennessee Oncology PLLC | Prostate Cancer, Cancer of the Prostate, Hormone Sensitive Prostate Cancer | 2 |
| Tennessee Oncology, PLLC | Acinar Cell Carcinoma, Advanced Cancer, Breast Cancer | 2 |
| Tennessee Oncology, PLLC - Chattanooga East | Advanced/Metastatic Urothelial Cancer, Cancer of the Prostate, Hormone Sensitive Prostate Cancer | 2 |
| WR-ClinSearch, LLC | Acute Migraine, Migraine | 2 |
| WR-Clinsearch, LLC | Atherosclerotic Cardiovascular Disease (ASCVD), COVID-19 SARS-CoV-2 Infection, Elevated Lp(a) | 2 |
| Woolfson Eye Institute | Forme Fruste Keratoconus (FFK), Keratoconus, Down Syndrome (DS) | 2 |
| Erlanger Medical Center | Atrial Fibrillation, Implant, Oral Anticoagulation | 2 |
Active & Upcoming Studies in Chattanooga (2026)
Recruiting trials in Chattanooga grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (42 active studies)
- Symbiotic-GU-06: A Study to Learn About PF-08634404 Alone or In Combination With Enfortumab Vedotin in Urothelial Cancer · Phase 1, Phase 2 · Pfizer
- Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer · Phase 1, Phase 2 · Pfizer
Diabetes & metabolic (12 active studies)
- A Study to Test Whether Survodutide Helps People With Type 2 Diabetes Control Their Blood Sugar · Phase 3 · Boehringer Ingelheim
- Evaluation of the Fully Closed Loop Omnipod® System in Type 2 Diabetes · Insulet Corporation
Neurology & pain (9 active studies)
- A Long-Term Safety Study of Elismetrep (K-304) in the Acute Treatment of Migraine · Phase 3 · Kallyope Inc.
- A Study to Evaluate the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine · Phase 3 · Kallyope Inc.
Cardiovascular (9 active studies)
Vaccines (2 active studies)
Pediatric (1 active study)
- CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D) · Phase 1, Phase 2 · COUR Pharmaceutical Development Company, Inc.
Common conditions studied in Chattanooga
- Carcinoma, Non-Small-Cell Lung (5 active studies)
- Generalized Myasthenia Gravis (4 active studies)
- AChR-Ab Seropositive Generalized Myasthenia Gravis (3 active studies)
- Breast Cancer (3 active studies)
- Chronic Lymphocytic Leukemia (3 active studies)
- Fallopian Tube Cancer (3 active studies)
Leading research sponsors in Chattanooga
- AstraZeneca
- Pfizer
- Boehringer Ingelheim
- GlaxoSmithKline
- Children's Oncology Group
Frequently asked questions
How many paid clinical trials are currently recruiting in Chattanooga?
There are approximately 130 recruiting clinical trials in Chattanooga, Tennessee listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Chattanooga pay participants?
Most recruiting trials in Chattanooga compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Chattanooga?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Chattanooga?
The most common conditions under active study in Chattanooga include Carcinoma, Non-Small-Cell Lung (5), Generalized Myasthenia Gravis (4), AChR-Ab Seropositive Generalized Myasthenia Gravis (3), Breast Cancer (3), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Chattanooga?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Chattanooga on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Chattanooga?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Chattanooga?
Recruiting research sites in Chattanooga include Erlanger Health System, GSK Investigational Site, Southeast Renal Research Institute, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Chattanooga right now?
The largest active categories in Chattanooga are Cancer & tumors (42), Diabetes & metabolic (12), Neurology & pain (9). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.