Non-invasive Prediction of EArly Cardiac rEjection
for Heart Transplant
Sites in Columbus +21 more locations
Sponsor: Vanderbilt University Medical Center
Sex: All·Age: 6 - 25
Code: NCT07770659·Recruiting·Listed Aug 18, 2026
Clinical Trials at Nationwide Children's Hospital
As of August 2026, 170 paid clinical trials are recruiting at Nationwide Children's Hospital, located at 700 CHILDRENS DR, COLUMBUS, OH 43205-2696, phone (614) 355-2103 in Columbus, Ohio. Active studies at this site cover conditions such as Acute Myeloid Leukemia, Breast Cancer and Chronic Lymphocytic Leukemia. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Columbus
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
Domatinostat With Sirolimus for Relapsed, Refractory Sarcoma and Osteosarcoma
for Sarcoma
Sites in Columbus +3 more locations
Sponsor: H. Lee Moffitt Cancer Center and Research Institute
Sex: All·Age: 12 - 40
Code: NCT07725380·Phase 1, Phase 2·Recruiting·Listed Jul 24, 2026
The MedMemos Study: Promoting Adherence to Medications in Pediatric Bone Marrow Transplant Patients
for Hematopoietic Cell Transplant
1 location in Columbus
Sponsor: Nationwide Children's Hospital
Sex: All·Age: 0 - 12
Code: NCT07718204·Recruiting·Listed Jul 21, 2026
Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG).
for Diffuse Intrinsic Pontine Glioma
Sites in Columbus +5 more locations
Sponsor: BrainChild Bio, Inc
Sex: All·Age: 1 - 26
Code: NCT07680439·Phase 2·Recruiting·Listed Jul 2026
174 clinical trials at Nationwide Children's Hospital
·Clear filters· Get a weekly email when new trials open in Columbus, OH.
A Phase 3 Trial to Compare IV BCV Versus IV CDV for Treatment of Adenovirus Infection After Allo-HCT
for Adenovirus Infections
Sites in Columbus, Cincinnati +30 more locations
Sponsor: SymBio Pharmaceuticals
Sex: All·Age: 2 Months+
Code: NCT07387367·Phase 3·Recruiting·Listed Feb 2026
PODOMOUNT-Basket, a Study to Test Whether BI 764198 Helps Adults and Adolescents With Different Types of Kidney Disease
for Proteinuric Kidney Diseases
Sites in Columbus, Cleveland +24 more locations
Sponsor: Boehringer Ingelheim
Sex: All·Age: 12+
Code: NCT07355296·Phase 2·Recruiting·Listed Jan 2026
A Study to Find Out if BI 764198 Helps Adults and Adolescents With a Kidney Condition Called Focal Segmental Glomerulosclerosis (FSGS)
for Focal Segmental Glomerulosclerosis
Sites in Columbus, Cincinnati +71 more locations
Sponsor: Boehringer Ingelheim
Sex: All·Age: 12+
Code: NCT07220083·Phase 3·Recruiting·Listed Oct 2025
Pompe Disease Registry Protocol
for Glycogen Storage Disease Type II
Sites in Columbus, Dublin +72 more locations
Sponsor: Genzyme, a Sanofi Company
Sex: All·Age: All ages
Code: NCT00231400·Recruiting·Listed Oct 2005
Fabry Disease Registry & Pregnancy Sub-registry
for Fabry Disease
Sites in Columbus, Dublin +72 more locations
Sponsor: Genzyme, a Sanofi Company
Sex: All·Age: All ages
Code: NCT00196742·Recruiting·Listed Sep 2005
A Study to Assess Growth in Children With Idiopathic Short Stature
for Idiopathic Short Stature
Sites in Columbus, Cincinnati +28 more locations
Sponsor: BioMarin Pharmaceutical
Sex: All·Age: 2 - 16
Code: NCT06309979·Recruiting·Listed Mar 2024
COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction
for Complex Congenital Heart Defect
Sites in Columbus, Cincinnati +19 more locations
Sponsor: Edwards Lifesciences
Sex: All·Age: All ages
Code: NCT02744677·Recruiting·Listed Apr 2016
International Collaborative Gaucher Group (ICGG) Gaucher Disease Registry & Pregnancy Sub-registry
for Gaucher Disease
Sites in Columbus, Dublin +68 more locations
Sponsor: Genzyme, a Sanofi Company
Sex: All·Age: All ages
Code: NCT00358943·Recruiting·Listed Aug 2006
Registry of Patients With a Diagnosis of Spinal Muscular Atrophy (SMA)
for Spinal Muscular Atrophy (SMA)
Sites in Columbus, Cincinnati +40 more locations
Sponsor: Novartis Pharmaceuticals
Sex: All·Age: All ages
Code: NCT04174157·Recruiting·Listed Nov 2019
Fontan Udenafil Exercise Longitudinal Assessment Trial - 2
for Single Ventricle Heart Disease
Sites in Columbus, Cincinnati +35 more locations
Sponsor: Mezzion Pharma Co. Ltd
Sex: All·Age: 12 - 18
Code: NCT05918211·Phase 3·Recruiting·Listed Jun 2023
Child and Adolescent Registry for Participants With Narcolepsy
for Narcolepsy
Sites in Columbus, Dublin +23 more locations
Sponsor: Jazz Pharmaceuticals
Sex: All·Age: Up to 17
Code: NCT04899947·Recruiting·Listed May 2021
A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)
for Obesity
Sites in Columbus, Cleveland +49 more locations
Sponsor: Eli Lilly and Company
Sex: All·Age: 6 - 17
Code: NCT06672549·Phase 3·Recruiting·Listed Nov 2024
REVEAL: A Phase 3 Study of Obudanersen (ION582) in Angelman Syndrome
for Angelman Syndrome
Sites in Columbus, Cincinnati +16 more locations
Sponsor: Ionis Pharmaceuticals, Inc.
Sex: All·Age: 2 - 50
Code: NCT06914609·Phase 3·Recruiting·Listed Apr 2025
4D-710 in Adult Patients With Cystic Fibrosis
for Cystic Fibrosis Lung
Sites in Columbus, Cleveland +16 more locations
Sponsor: 4D Molecular Therapeutics
Sex: All·Age: 18+
Code: NCT05248230·Phase 2·Recruiting·Listed Feb 2022
A Study to Investigate the Safety and Effectiveness of a Coagulation Factor IX Gene Insertion Therapy (REGV131-LNP1265) in Pediatric, Adolescent and Adult Participants With Hemophilia B
for Hemophilia B
Sites in Columbus +14 more locations
Sponsor: Regeneron Pharmaceuticals
Sex: Male·Age: 2+
Code: NCT06379789·Phase 1, Phase 2·Recruiting·Listed Apr 2024
A Study of SGT-003 Gene Therapy in Duchenne Muscular Dystrophy (INSPIRE DUCHENNE)
for Duchenne Muscular Dystrophy
Sites in Columbus +11 more locations
Sponsor: Solid Biosciences Inc.
Sex: Male·Age: 0 - 17
Code: NCT06138639·Phase 1, Phase 2·Recruiting·Listed Nov 2023
A Clinical Study to Evaluate the Safety and Efficacy of ETX101 in Infants and Children With SCN1A-Positive Dravet Syndrome
for Dravet Syndrome
Sites in Columbus +10 more locations
Sponsor: Encoded Therapeutics
Sex: All·Age: 6 Months - 17
Code: NCT05419492·Phase 1, Phase 2·Recruiting·Listed Jun 2022
Study of Olutasidenib and Temozolomide in HGG
for High Grade Glioma
Sites in Columbus, Cincinnati +9 more locations
Sponsor: Rigel Pharmaceuticals
Sex: All·Age: 12 - 39
Code: NCT06161974·Phase 2·Recruiting·Listed Dec 2023
Study of Sparsentan Treatment in Pediatrics With Proteinuric Glomerular Diseases
for Focal Segmental Glomerulosclerosis
Drug: Sparsentan
Sites in Columbus +16 more locations
Sponsor: Travere Therapeutics, Inc.
Sex: All·Age: 1 - 17
Code: NCT05003986·Phase 2·Recruiting·Listed Aug 2021
Study of Lurbinectedin Monotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Ewing Sarcoma
for Refractory Ewing Sarcoma
Drug: Lurbinectedin
Sites in Columbus, Cincinnati +12 more locations
Sponsor: Jazz Pharmaceuticals
Sex: All·Age: 2 - 30
Code: NCT05734066·Phase 1, Phase 2·Recruiting·Listed Feb 2023
Minima Stent System Post- Approval Study (PAS)
for Pulmonary Artery Stenosis
Sites in Columbus, Cincinnati +13 more locations
Sponsor: Renata Medical
Sex: All·Age: All ages
Code: NCT06828770·Recruiting·Listed Feb 2025
A Multicenter Multinational Observational Study of Children With Hypochondroplasia
for Hypochondroplasia
Sites in Columbus, Akron +14 more locations
Sponsor: BioMarin Pharmaceutical
Sex: All·Age: Up to 15
Code: NCT06212947·Recruiting·Listed Jan 2024
Phase 2 Study of SAT-3247 in Pediatric Ambulatory Patients
for Duchenne Muscular Dystrophy
Sites in Columbus +6 more locations
Sponsor: Satellos Bioscience, Inc.
Sex: Male·Age: 7 - 9
Code: NCT07287189·Phase 2·Recruiting·Listed Dec 2025
Starlight Cardiovascular Lifeline Ductus Arteriosus Stent IDE Study
for Congenital Heart Disease
Sites in Columbus, Cincinnati +7 more locations
Sponsor: Starlight Cardiovascular Inc
Sex: All·Age: 1 Minute - 6 Months
Code: NCT07114718·Recruiting·Listed Aug 2025
Infant Formula in Infants and Children With Cow's Milk Allergy
for Cow's Milk Allergy
Sites in Columbus, Cincinnati +6 more locations
Sponsor: Abbott Nutrition
Sex: All·Age: 3 Months - 12
Code: NCT06456541·Recruiting·Listed Jun 2024
Growth and Tolerance of Plant-based Enteral Formulas in Children Ages 12-17 Months.
for Formula Dependent Children 1 to 2 Years of Age
1 location in Columbus
Sponsor: Kate Farms Inc
Sex: All·Age: 12 Months - 17 Months
Code: NCT07231705·Recruiting·Listed Nov 2025
Gene Correction in Autologous CD34+ Hematopoietic Stem Cells (HbS to HbA) to Treat Severe Sickle Cell Disease
for Sickle Cell Disease
Sites in Columbus +5 more locations
Sponsor: Kamau Therapeutics
Sex: All·Age: 12 - 50
Code: NCT04819841·Phase 1, Phase 2·Recruiting·Listed Mar 2021
KiteLock 4% EDTA Lock Solution for the Prevention of Occlusions in Children With Intestinal Failure
for Pediatric Intestinal Failure
Sites in Columbus, Cincinnati +6 more locations
Sponsor: SterileCare Inc.
Sex: All·Age: 4 Weeks - 18
Code: NCT05879835·Recruiting·Listed May 2023
NXT Post-Market Clinical Follow-up
for Urinary Incontinence
Sites in Columbus +4 more locations
Sponsor: Laborie Medical Technologies Inc.
Sex: All·Age: All ages
Code: NCT06336304·Recruiting·Listed Mar 2024
Safety Study of SMOFlipid to Evaluate the Risk of Developing EFAD and/or PNAC in Pediatric and Adult Patients
for Malnutrition, Child
Sites in Columbus +4 more locations
Sponsor: Fresenius Kabi
Sex: All·Age: 1 Month - 17
Code: NCT06049680·Phase 4·Recruiting·Listed Sep 2023
Modulation of SERCA2a of Intra-Myocytic Calcium Trafficking in Cardiomyopathy Secondary to Duchenne Muscular Dystrophy
for DMD-Associated Dilated Cardiomyopathy
Sites in Columbus, Cincinnati +1 more location
Sponsor: Sardocor Corp.
Sex: Male·Age: 18+
Code: NCT06224660·Phase 1·Recruiting·Listed Jan 2024
Teenthrive 2: Treatments for Improving Mood in Teens
for Depression in Adolescence
Sites in Columbus +1 more location
Sponsor: Butler Hospital
Sex: All·Age: 12 - 18
Code: NCT07475845·Recruiting·Listed Mar 2026
Study to Enable New Diagnostics for Pulmonary Microbes in People With CF
for Cystic Fibrosis (CF)
Sites in Columbus +8 more locations
Sponsor: Chris Goss
Sex: All·Age: 16+
Code: NCT07312734·Recruiting·Listed Dec 2025
Bowel Continence Across the Lifespan in People With Spina Bifida
for Spina Bifida
Sites in Columbus, Cincinnati +22 more locations
Sponsor: David Chu
Sex: All·Age: 5+
Code: NCT07390318·Recruiting·Listed Feb 2026
Feasibility of Light Therapy in the Pediatric Intensive Care Unit (ICU)
for Circadian Dysregulation
1 location in Columbus
Sponsor: Laura Beth Kalvas
Sex: All·Age: 4 - 17
Code: NCT07384585·Recruiting·Listed Feb 2026
Pathways to Prevention Food-is-Medicine Trial
for Heart Disease
1 location in Columbus
Sponsor: Amrik Singh Khalsa
Sex: All·Age: 6+·Accepts healthy volunteers
Code: NCT07380243·Recruiting·Listed Feb 2026
A First-in-human Study of S230815 in Pediatric Participants With KCNT1-related Developmental and Epileptic Encephalopathy
for Epileptic Encephalopathy
Sites in Columbus +4 more locations
Sponsor: Institut de Recherches Internationales Servier
Sex: All·Age: 2 - 12
Code: NCT07227857·Phase 1, Phase 2·Recruiting·Listed Nov 2025
Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors
for Childhood Extracranial Germ Cell Tumor
Sites in Columbus, Grove City +380 more locations
Sponsor: Children's Oncology Group
Sex: All·Age: All ages
Code: NCT03067181·Phase 3·Recruiting·Listed Mar 2017
A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab
for Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8
Drug: Nivolumab
Sites in Columbus, Dayton +378 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 5 - 60
Code: NCT05675410·Phase 3·Recruiting·Listed Jan 2023
Metastatic Ewing's Trial Testing Schedule Enhancement to Improve Outcomes
for Metastatic Ewing Sarcoma
Sites in Columbus, Cleveland +18 more locations
Sponsor: H. Lee Moffitt Cancer Center and Research Institute
Sex: All·Age: 1+
Code: NCT07194044·Phase 1·Recruiting·Listed Sep 2025
Common conditions studied in Columbus
- Acute Myeloid Leukemia (20 active studies)
- Breast Cancer (19 active studies)
- Chronic Lymphocytic Leukemia (18 active studies)
- Ovarian Cancer (17 active studies)
- Endometrial Cancer (16 active studies)
- Malignant Solid Neoplasm (14 active studies)
Leading research sponsors in Columbus
- Ohio State University
- Ohio State University Comprehensive Cancer Center
- National Cancer Institute (NCI)
- Nationwide Children's Hospital
- AstraZeneca
Frequently asked questions
How many paid clinical trials are currently recruiting in Columbus?
There are approximately 1,365 recruiting clinical trials in Columbus, Ohio listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Columbus pay participants?
Most recruiting trials in Columbus compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Columbus?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Columbus?
The most common conditions under active study in Columbus include Acute Myeloid Leukemia (20), Breast Cancer (19), Chronic Lymphocytic Leukemia (18), Ovarian Cancer (17), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Columbus?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Columbus on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Columbus?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Columbus?
Recruiting research sites in Columbus include Ohio State University Comprehensive Cancer Center, Nationwide Children's Hospital, The Ohio State University, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Columbus right now?
The largest active categories in Columbus are Cancer & tumors (492), Cardiovascular (79), Neurology & pain (65). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
What is the address of Nationwide Children's Hospital?
Nationwide Children's Hospital is located at 700 CHILDRENS DR, COLUMBUS, OH 43205-2696. Use the Google Maps link in the intro above to get directions.
How do I contact Nationwide Children's Hospital?
You can reach Nationwide Children's Hospital by phone at (614) 355-2103. For questions about a specific trial, use the study coordinator contact listed on the individual study record — click any trial title above to open it.
Browse more clinical trials
Other cities in Ohio
Cleveland, OH(1,259)Cincinnati, OH(1,081)Dayton, OH(180)Canton, OH(149)Toledo, OH(123)Akron, OH(121)Centerville, OH(80)West Chester, OH(58)Mayfield Heights, OH(53)Franklin, OH(52)Beachwood, OH(51)Greenville, OH(50)Mentor, OH(49)Westlake, OH(49)Troy, OH(48)Dublin, OH(45)Maumee, OH(44)Kettering, OH(43)Sylvania, OH(41)Marion, OH(37)Westerville, OH(34)Beavercreek, OH(30)Zanesville, OH(30)Avon, OH(28)Mansfield, OH(28)Middleburg Heights, OH(28)Springfield, OH(27)Youngstown, OH(27)Lima, OH(26)Boardman, OH(25)Delaware, OH(25)Athens, OH(24)Newark, OH(24)Perrysburg, OH(24)Chillicothe, OH(23)Independence, OH(23)Belpre, OH(22)North Canton, OH(20)Mount Vernon, OH(19)Portsmouth, OH(19)Fairborn, OH(18)Findlay, OH(18)Gahanna, OH(18)Grove City, OH(18)Marietta, OH(18)Marysville, OH(17)Pickerington, OH(17)Hilliard, OH(16)Sandusky, OH(16)Lancaster, OH(15)Mason, OH(15)New Albany, OH(15)Chardon, OH(14)Parma, OH(14)Warren, OH(14)Wooster, OH(14)Springboro, OH(12)Fairfield, OH(10)Blue Ash, OH(9)Liberty Township, OH(9)