Paid Clinical Trials in Mayfield Heights, OH
As of July 2026, 52 paid clinical trials are recruiting in Mayfield Heights, Ohio. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Mayfield Heights offers studies at sites including Hillcrest Hospital Cancer Center for conditions such as Atopic Dermatitis, Breast Cancer, Plaque Psoriasis, Amblyopia. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Mayfield Heights
Trials by drug in Mayfield Heights
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Newly added in Mayfield Heights
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
50 clinical trials
A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)
A Study Evaluating BFB759 in Moderate to Severe Hidradenitis Suppurativa
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer
Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer
Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants With Psoriasis (PRAGMATYK)
Ocular Assessments in Patients Treated With Tivdak® in Recurrent or Metastatic Cervical Cancer
A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)
A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
Phase 2/3 Trial of Izalontamab Brengitecan vs Platinum-based Chemotherapy for Metastatic Urothelial Cancer With Disease Progression on or After Immunotherapy
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer
A Study to Evaluate the Efficacy, Safety, and Drug Levels of Deucravacitinib (BMS-986165) in Adolescent Participants With Moderate to Severe Plaque Psoriasis
Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer
Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer
A Study To Learn About Two Study Medicines (PF-07275315 And PF-07264660) In People Who Have Moderate To Severe Atopic Dermatitis
Study of Navtemadlin add-on to Ruxolitinib in JAK Inhibitor-Naïve Patients With Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
A Study to Evaluate D-2570 in Participants With Moderate to Severe Plaque Psoriasis
A Long-Term Study of Zasocitinib in Children and Teenagers With Plaque Psoriasis
A Study of Zasocitinib in Adults With Hidradenitis Suppurativa
A Study to Evaluate the Efficacy and Safety of IMG-007 in Adult Participants With Moderate-to-Severe Atopic Dermatitis
Study of the Efficacy and Safety of ICP-332 in Participants With Prurigo Nodularis
Phase 2 Study to Evaluate EI-001 in Non-segmental Vitiligo Patients
Visugromab in Cachexia International Trial
A 16-week Trial to Investigate the Efficacy and Safety of Delgocitinib Cream 20 mg/g in Adult Participants With Mild to Severe Palmoplantar Pustulosis
Phase II Study of Artesunate Ointment for the Treatment of Vulvar High Grade Squamous Intraepithelial Lesions (Vulvar HSIL, VIN2/3)
Artesunate Vaginal Inserts for the Treatment of Cervical Intraepithelial Neoplasia (CIN2/3)
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study
Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer
Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer
Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial
Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response
Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer
Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma
Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer
De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)
Top Research Study Locations in Mayfield Heights
Researchers run research studies in Mayfield Heights, OH at 21 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Hillcrest Hospital Cancer Center | Ovarian Carcinoma, Stage IIIB Lung Cancer AJCC v8, Advanced Lung Non-Squamous Non-Small Cell Carcinoma | 16 |
| Cleveland Clinic - Hillcrest Hospital | Neoplasm Metastasis, Breast Neoplasms, Extensive-stage Small-cell Lung Cancer | 5 |
| Hillcrest Hospital | HPV Infection, Pre-Cancerous Dysplasia, Breast Cancer | 5 |
| Apex Clinical Research Center | Plaque Psoriasis, Atopic Dermatitis, Prurigo Nodularis (PN) | 5 |
| Apex Clinical Research Center, LLC | Hidradenitis Suppurativa (HS), Plaque Psoriasis | 2 |
| Cleveland Clinic Hillcrest Hospital | Cancer-associated Cachexia, Cervical Cancer | 2 |
| Inmagene | Atopic Dermatitis, Atopic Dermatitis Eczema, Eczema | 2 |
| Rainbow Babies and Children's Hospital Dept of Ophth | Amblyopia | 2 |
| Apex Clinical Research Center, LLC (Mayfield) | Non-segmental Vitiligo | 1 |
| Apex Clinical Research Center, LLC. | Hidradenitis Suppurativa | 1 |
| Cleveland Clinic - Hillcrest Hospital-Hillcrest Hospital Cancer Center | Lymphoma, Large B-Cell, Diffuse | 1 |
| Cleveland Clinic Cancer Center Hillcrest Hospital | Colorectal Neoplasms | 1 |
| Cleveland Clinic Hillcrest | Blood Pressure Control | 1 |
| Clinical Study Site | Metastatic Colorectal Cancer (CRC) | 1 |
| Enveda Investigative Site | Atopic Dermatitis (AD) | 1 |
| Hillcrest Hospital - Cleveland Clinic | MF, Myelofibrosis, Post-ET Myelofibrosis | 1 |
| LEO Pharma Investigation Site | Palmoplantar Pustulosis | 1 |
| Local Institution - 0924 | Non-small Cell Lung Cancer (NSCLC) | 1 |
| Massive Bio SYNERGY-AI site | BRCA Gene Rearrangement, Bladder Cancer, Breast Cancer | 1 |
| Study Center | Psoriasis | 1 |
| UH Hospitals | Bacterial Vaginosis, Cancer, Candidiasis | 1 |
Active & Upcoming Studies in Mayfield Heights (2026)
Recruiting trials in Mayfield Heights grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (27 active studies)
- Visugromab in Cachexia International Trial · Phase 2, Phase 3 · CatalYm GmbH
- A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201) · Phase 3 · Bristol-Myers Squibb
Vaccines (1 active study)
Common conditions studied in Mayfield Heights
- Atopic Dermatitis (3 active studies)
- Breast Cancer (3 active studies)
- Plaque Psoriasis (3 active studies)
- Amblyopia (2 active studies)
- Atopic Dermatitis Eczema (2 active studies)
- Cancer (2 active studies)
Leading research sponsors in Mayfield Heights
- NRG Oncology
- National Cancer Institute (NCI)
- Bristol-Myers Squibb
- SWOG Cancer Research Network
- BioNTech SE
Frequently asked questions
How many paid clinical trials are currently recruiting in Mayfield Heights?
There are approximately 52 recruiting clinical trials in Mayfield Heights, Ohio listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Mayfield Heights pay participants?
Most recruiting trials in Mayfield Heights compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Mayfield Heights?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Mayfield Heights?
The most common conditions under active study in Mayfield Heights include Atopic Dermatitis (3), Breast Cancer (3), Plaque Psoriasis (3), Amblyopia (2), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Mayfield Heights?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Mayfield Heights on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Mayfield Heights?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Mayfield Heights?
Recruiting research sites in Mayfield Heights include Hillcrest Hospital Cancer Center, Cleveland Clinic - Hillcrest Hospital, Hillcrest Hospital, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Mayfield Heights right now?
The largest active categories in Mayfield Heights are Cancer & tumors (27), Vaccines (1). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.