Paid Clinical Trials in Independence, OH
As of July 2026, 23 paid clinical trials are recruiting in Independence, Ohio. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Independence offers studies at sites including Cleveland Clinic Cancer Center Independence for conditions such as Major Depressive Disorder, Alzheimer Disease, Major Depressive Disorder (MDD), Major Depressive Disorder With Anxious Distress. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Independence
Trials by drug in Independence
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21 clinical trials
A Study of Brenipatide in Adult Participants With Schizophrenia
A Phase 2 Study of Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder
A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)
Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder
A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)
A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)
A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (X-NOVA3)
Study of Navtemadlin add-on to Ruxolitinib in JAK Inhibitor-Naïve Patients With Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib
A Study to Evaluate the Effectiveness of Valbenazine in Adult Participants With Tardive Dyskinesia (TD) Who Remain Symptomatic While Receiving or After Stopping a Vesicular Monoamine Transporter 2 (VMAT2) Inhibitor
Safety and Efficacy of EXV-802 and EXV-801 in the Treatment of Agitation in Alzheimer's Disease Dementia
A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-5)
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial
Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer
S1703 Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Receptor Positive Her2 Negative Metastatic Breast Cancer
S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity
A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease Psychosis
Top Research Study Locations in Independence
Researchers run research studies in Independence, OH at 8 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Cleveland Clinic Cancer Center Independence | Anatomic Stage IV Breast Cancer AJCC v8, Breast Cancer, Cardiotoxicity | 7 |
| Insight Clinical Trials | Agitation Associated With Alzheimer's Disease Dementia, Major Depressive Disorder, Post Traumatic Stress Disorder | 5 |
| Insight Clinical Trials LLC | Major Depressive Disorder | 3 |
| Insight Clinical Trials LLC - Independence | Alzheimer Disease, Psychosis | 2 |
| Seaport Investigator Site | Major Depressive Disorder (MDD), Major Depressive Disorder With Anxious Distress | 2 |
| Cleveland Clinic Cancer Center Independence Family Health Center | Colorectal Neoplasms | 1 |
| Independence Family Health Center - Cleveland Clinic | MF, Myelofibrosis, Post-ET Myelofibrosis | 1 |
| Neurocrine Clinical Site | Bipolar Disorder, Major Depressive Disorder, Schizoaffective Disorder | 1 |
Active & Upcoming Studies in Independence (2026)
Recruiting trials in Independence grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (7 active studies)
- Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer · Phase 3 · NRG Oncology
- Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25 · Phase 3 · NRG Oncology
Mental health & behavior (2 active studies)
- A Study of Brenipatide in Adult Participants With Schizophrenia · Phase 2 · Eli Lilly and Company
- A Study to Evaluate the Effectiveness of Valbenazine in Adult Participants With Tardive Dyskinesia (TD) Who Remain Symptomatic While Receiving or After Stopping a Vesicular Monoamine Transporter 2 (VMAT2) Inhibitor · Phase 4 · Neurocrine Biosciences
Neurology & pain (2 active studies)
- A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-5) · Phase 3 · Bristol-Myers Squibb
- A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4) · Phase 3 · Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Common conditions studied in Independence
- Major Depressive Disorder (5 active studies)
- Alzheimer Disease (2 active studies)
- Major Depressive Disorder (MDD) (2 active studies)
- Major Depressive Disorder With Anxious Distress (2 active studies)
- Schizophrenia (2 active studies)
- Agitation Associated With Alzheimer's Disease Dementia (1 active study)
Leading research sponsors in Independence
- NRG Oncology
- National Cancer Institute (NCI)
- SWOG Cancer Research Network
- Seaport Therapeutics
- Syndeio Biosciences, Inc
Frequently asked questions
How many paid clinical trials are currently recruiting in Independence?
There are approximately 23 recruiting clinical trials in Independence, Ohio listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Independence pay participants?
Most recruiting trials in Independence compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Independence?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Independence?
The most common conditions under active study in Independence include Major Depressive Disorder (5), Alzheimer Disease (2), Major Depressive Disorder (MDD) (2), Major Depressive Disorder With Anxious Distress (2), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Independence?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Independence on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Independence?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Independence?
Recruiting research sites in Independence include Cleveland Clinic Cancer Center Independence, Insight Clinical Trials, Insight Clinical Trials LLC, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Independence right now?
The largest active categories in Independence are Cancer & tumors (7), Mental health & behavior (2), Neurology & pain (2). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.