Paid Clinical Trials in Orange City, FL
As of August 2026, 53 paid clinical trials are recruiting in Orange City, Florida. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Orange City offers studies at sites including Mid Florida Hematology and Oncology Center for conditions such as Non-small Cell Lung Cancer, Non-Small Cell Lung Cancer, Carcinoma, Non-Small-Cell Lung, Melanoma. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Orange City
Trials by drug in Orange City
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51 clinical trials
A Study of Brenipatide in Adult Participants With Major Depressive Disorder
A 26-Wk Study to Assess Safety & Efficacy of Tenapanor for T/t of Chronic Idiopathic Constipation in Adults
Effectiveness and Adverse-effect Switch Evaluation of Xanomeline and Trospium Chloride (KarXT)
Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
Symbiotic-Lung-20: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Different Anticancer Agents in Advanced Cancers
Efficacy and Safety of Ribupatide Administered Once Weekly Compared With Semaglutide and Placebo in Participants Living With Obesity Who Do Not Have Diabetes
Efficacy and Safety of Ribupatide Administered Once Weekly in Participants Living With Obesity or Overweight and Diabetes
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
Beamion LUNG-3: Adjuvant Zongertinib vs Standard Treatment in People With Completely Resected Stage II-IIIB NSCLC Harboring Activating HER2 TKD Mutations
Study to Assess Adverse Events and Disease Activity of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Children and Adolescents (Ages 6-17)
A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)
A Study of ZL-1310 Versus Investigator's Choice of Therapy in Participants With Relapsed Small Cell Lung Cancer (DLLEVATE)
This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.
A Study of Vedolizumab in Adults With Ulcerative Colitis or Crohn's Disease in the Community Setting
A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)
A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002)
A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)
A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric Participants Participants (10 to 17 Years of Age) With Bipolar I Disorder.
A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)
A Study of Disitamab Vedotin in Adults With HER2 Expressing Advanced Breast Cancer
Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease
Study to Evaluate Adverse Events and Efficacy of Intravenous (IV) Telisotuzumab Adizutecan in Combination With a PD-1 Immune Checkpoint Inhibitor in Adult Participants With Advanced or Metastatic Non-Squamous NSCLC With No Prior Treatment for Advanced Disease, and No Actionable Genomic Alterations
Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer
A U.S. Registry of Eosinophilic Esophagitis Pediatric, Adolescent and Adult Patients Treated With DUPIXENT® As Standard of Care
A Study to Evaluate the Risk of Tumor Lysis Syndrome (TLS) in Adult Participants Receiving Oral Venetoclax in Combination With Intravenously Infused Obinutuzumab or Oral Acalabrutinib for Previously Untreated Chronic Lymphocytic Leukemia (CLL)
A Phase 2 Study of Vosoritide in Children With Idiopathic Short Stature
Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Esophagus
Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Bowel
Prospective Study to Assess a Diagnostic Aid for Cancer
Evaluation of SPN-812 (Viloxazine Extended-release Capsule) in Preschool-age Children With ADHD
A Study to Evaluate the Long-term Safety and Tolerability of KarXT and KarX-EC for the Treatment of Schizophrenia and Autism-Related Irritability in Adolescents, Respectively
Efficacy, Safety, and Tolerability of NBI-1065890 Versus Placebo in Adults With Tardive Dyskinesia
Symbiotic-Lung-04: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Extensive-Stage Small Cell Lung Cancer
A Study to Compare the Efficacy and Safety of BMS-986489 (BMS-986012+ Nivolumab Fixed Dose Combination) in Combination With Carboplatin Plus Etoposide to That of Atezolizumab With Carboplatin Plus Etoposide as First-Line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer (TIGOS).
Study of Trastuzumab Deruxtecan, Pembrolizumab, and Platinum-based Chemotherapy in First-line HER2 Overexpressing Non-small Cell Lung Cancer
A Phase I Clinical Study to Evaluate the PK Profile, Efficacy, Safety and Immunogenicity of HLX17 vs. Keytruda® in Multiple Resected Solid Tumors
A Study to Assess Adverse Events, Change in Disease Activity of Intravenous Telisotuzumab Adizutecan in Combination With Osimertinib as First-Line Treatment in Adult Participants With Locally Advanced Unresectable or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer
Efficacy & Safety of Olvimulogene Nanivacirepvec & Platinum-doublet + Physician's Choice of Immune Checkpoint Inhibitor Compared to Docetaxel in NSCL Cancer
Top Research Study Locations in Orange City
Researchers run research studies in Orange City, FL at 21 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Mid Florida Hematology and Oncology Center | Non-Small Cell Lung Cancer, Carcinoma, Non-Small-Cell Lung, Carcinoma, Non-Small-Cell Lung (NSCLC) | 21 |
| Medical Research Group of Central Florida | Attention-Deficit/Hyperactivity Disorder, Depression, Major Depressive Disorder (MDD) | 5 |
| Optimal Research Sites | Depressive Disorder, Major, Diabetes Mellitus, Type 2, Idiopathic Short Stature | 3 |
| Florida Cancer Specialists | Advanced Non-Small Cell Lung Cancer, Breast Cancer, Breast Neoplasms | 2 |
| Gastroenterology of Greater Orlando | Cancer, Eosinophilic Esophagitis (EoE) | 2 |
| Hillcrest Medical Research | Bowel; Stricture, Esophageal Stricture | 2 |
| Kailera Clinical Site | Obesity, Obesity With Diabetes, Overweight With Diabetes | 2 |
| Mid-Florida Hematology & Oncology Centers, P.A. | Non-small Cell Lung Cancer, Patients With Chemotherapy-Induced Thrombocytopenia | 2 |
| Neurocrine Clinical Site | Tardive Dyskinesia, Bipolar Disorder, Major Depressive Disorder | 2 |
| Alpha Clinical Research Centers LLC | Advanced Non-Small Cell Lung Cancer, Carcinoma, Non-Small-Cell Lung, Carcinoma, Non-Small-Cell Lung (NSCLC) | 1 |
| Florida Cancer Specialists - North | Limited Stage Small Cell Lung Cancer | 1 |
| Florida Hospital FISH | Anal Cancer, Bile Duct Cancer, Bladder Cancer | 1 |
| Harmony Clinical Research - Orlando | Chronic Idiopathic Constipation (CIC) | 1 |
| Hillcrest Medical Research, LLC | Crohn's Disease | 1 |
| Local Institution - 0166 | Autism-Related Irritability, Schizophrenia | 1 |
| Medical Research of Central Florida | Schizophrenia | 1 |
| Mid Florida Cancer Centers | Non-small Cell Lung Cancer | 1 |
| Mid Florida Center | Advanced Solid Tumors | 1 |
| Mid Florida Hematology and Oncology Centers | Cancer-associated Cachexia | 1 |
| The Clinical Trials Network CTNX LLC | Crohn's Disease, Ulcerative Colitis | 1 |
| Zai Lab | Small-cell Lung Cancer | 1 |
Active & Upcoming Studies in Orange City (2026)
Recruiting trials in Orange City grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (28 active studies)
- Visugromab in Cachexia International Trial · Phase 2, Phase 3 · CatalYm GmbH
- Symbiotic-Lung-20: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Different Anticancer Agents in Advanced Cancers · Phase 1, Phase 2 · Pfizer
Mental health & behavior (5 active studies)
- A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD) · Phase 2 · Tonix Pharmaceuticals, Inc.
- A Study to Evaluate the Long-term Safety and Tolerability of KarXT and KarX-EC for the Treatment of Schizophrenia and Autism-Related Irritability in Adolescents, Respectively · Phase 3 · Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Diabetes & metabolic (3 active studies)
- AMAZE 8: A Research Study Investigating How Well the Medicine NNC0487-0111 Compared to Semaglutide Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight · Phase 3 · Novo Nordisk A/S
- Efficacy and Safety of Ribupatide Administered Once Weekly in Participants Living With Obesity or Overweight and Diabetes · Phase 3 · Kailera
Neurology & pain (2 active studies)
- Long-term Extension Study to Assess Safety and Tolerability of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Pediatric Participants (Ages 6-17) · Phase 3 · AbbVie
- Study to Assess Adverse Events and Disease Activity of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Children and Adolescents (Ages 6-17) · Phase 3 · AbbVie
Common conditions studied in Orange City
- Non-small Cell Lung Cancer (7 active studies)
- Non-Small Cell Lung Cancer (5 active studies)
- Carcinoma, Non-Small-Cell Lung (3 active studies)
- Melanoma (3 active studies)
- Schizophrenia (3 active studies)
- Breast Cancer (2 active studies)
Leading research sponsors in Orange City
- AbbVie
- Pfizer
- Merck Sharp & Dohme LLC
- AstraZeneca
- Bristol-Myers Squibb
Frequently asked questions
How many paid clinical trials are currently recruiting in Orange City?
There are approximately 53 recruiting clinical trials in Orange City, Florida listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Orange City pay participants?
Most recruiting trials in Orange City compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Orange City?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Orange City?
The most common conditions under active study in Orange City include Non-small Cell Lung Cancer (7), Non-Small Cell Lung Cancer (5), Carcinoma, Non-Small-Cell Lung (3), Melanoma (3), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Orange City?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Orange City on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Orange City?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Orange City?
Recruiting research sites in Orange City include Mid Florida Hematology and Oncology Center, Medical Research Group of Central Florida, Optimal Research Sites, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Orange City right now?
The largest active categories in Orange City are Cancer & tumors (28), Mental health & behavior (5), Diabetes & metabolic (3). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.