Paid Clinical Trials in Illinois

Illinois has 2,847 paid clinical trials enrolling now across cities including Chicago, Peoria and Evanston. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Illinois include Northwestern Medicine, University of Chicago Medicine and Rush, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 14, 2026.

Filter results

Filter results

State

City

Recruitment status

Phase

Study type

Intervention

Condition

Sex

Age

Healthy volunteers only

2,519 clinical trials

Get a weekly email when new trials open in Chicago, IL.

Vertebral Artery Origin Treatment Via Endovascular Techniques Registry (VOTER)

for Vertebral Artery Stenosis

Sites in Winfield +9 more locations

Sponsor: St. Louis University

Sex: All·Age: 18 - 90

Code: NCT03999983·Recruiting·Listed Jun 2019

Apply to this trial

Breaking Sitting with High-intensity Interval Training for Brain Health

for Aging

1 location in Urbana

Sponsor: University of Illinois at Urbana-Champaign

Sex: All·Age: 40 - 75·Accepts healthy volunteers

Code: NCT06243016·Recruiting·Listed Feb 2024

Apply to this trial

Long Term Outcomes Following Hernia Repair With Mesh

for Abdominal Hernia

1 location in Evanston

Sponsor: Endeavor Health

Sex: All·Age: 18+

Code: NCT04578340·Recruiting·Listed Oct 2020

Apply to this trial

International REgistry of COnservative or Radical Treatment of Localized Kidney Tumors

for Kidney Cancer

Sites in Chicago +6 more locations

Sponsor: Azienda Ospedaliero-Universitaria Careggi

Sex: All·Age: 18+

Code: NCT05363657·Recruiting·Listed May 2022

Apply to this trial

Glanatec(R) for Descemet Stripping in Fuch's Endothelial Dystrophy

for Fuchs' Endothelial Dystrophy

1 location in Glenview

Sponsor: Marian Macsai, MD

Sex: All·Age: 18 - 91

Code: NCT03249337·Phase 4·Recruiting·Listed Aug 2017

Apply to this trial

Methadone and Quality of Postoperative Recovery

for Quality of Recovery Scores

1 location in Evanston

Sponsor: Endeavor Health

Sex: All·Age: 18 - 90

Code: NCT03168958·Phase 4·Recruiting·Listed May 2017

Apply to this trial

Effect of Methadone and Hydromorphone on the QT Interval After Anesthesia and Surgery

for EKG-QT Prolongation

1 location in Evanston

Sponsor: Endeavor Health

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT03893734·Phase 4·Recruiting·Listed Mar 2019

Apply to this trial

Efficacy and Safety of Oral Rifaximin in Patients With Active Microscopic Colitis

for Microscopic Colitis

1 location in Evanston

Sponsor: Eugene F Yen, MD

Sex: All·Age: 18+

Code: NCT04043897·Phase 2·Recruiting·Listed Aug 2019

Apply to this trial

Safety and Feasibility of an ExoNET for Supination Assistance for Stroke Survivors

for Stroke

1 location in Chicago

Sponsor: Shirley Ryan AbilityLab

Sex: All·Age: 40 - 70·Accepts healthy volunteers

Code: NCT06655636·Recruiting·Listed Oct 2024

Apply to this trial

Surgical Treatments for Postamputation Pain

for Residual Limb Pain

Sites in Chicago +2 more locations

Sponsor: Prometei Pain Rehabilitation Center

Sex: All·Age: 18+

Code: NCT05009394·Recruiting·Listed Aug 2021

Apply to this trial

Knotless Implants As an Alternative for Capsular Closure in Primary Hip Arthroscopy: a Prospective, Multi-Center Study

for Femoro Acetabular Impingement

1 location in Des Plaines

Sponsor: American Hip Institute

Sex: All·Age: 18 - 60

Code: NCT06500364·Phase 4·Recruiting·Listed Jul 2024

Apply to this trial

Impact of Artificial Intelligence on Trainee Polyp Miss Rates

for Colon Polyps

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT06676930·Recruiting·Listed Nov 2024

Apply to this trial

Mindfulness, Exercise, and Nutrition To Optimize Resilience (MENTOR)

for Disabled Persons

1 location in Chicago

Sponsor: Shirley Ryan AbilityLab

Sex: All·Age: 18+

Code: NCT06560619·Recruiting·Listed Aug 2024

Apply to this trial

Duration of Ureteral Rest Prior to Ureteral Reconstruction Surgery

for Ureteral Stricture

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT06384079·Recruiting·Listed Apr 2024

Apply to this trial

Post-Vent, the Sequelae: Personalized Prognostic Modeling for Consequences of Neonatal Intermittent Hypoxemia in Preterm Infants at Pre-School Age

for Premature Birth

1 location in Chicago

Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago

Sex: All·Age: 30 Weeks - 83 Months

Code: NCT05336890·Recruiting·Listed Apr 2022

Apply to this trial

Anti-inflammatory Drugs and Serum Prostate-Specific Antigen Test

for Prostate Cancer

Sites in Chicago +2 more locations

Sponsor: Albany Medical College

Sex: Male·Age: 18 - 80

Code: NCT05629494·Phase 4·Recruiting·Listed Nov 2022

Apply to this trial

RCT Glargine vs NPH for Treatment of DM in Pregnancy

for Diabetes Mellitus in Pregnancy

1 location in Maywood

Sponsor: Loyola University

Sex: Female·Age: 18+

Code: NCT06619301·Phase 3·Recruiting·Listed Oct 2024

Apply to this trial

Error-enhanced Learning & Recovery in 2 & 3 Dimensions

for Stroke

3 locations in Chicago

Sponsor: Shirley Ryan AbilityLab

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05180786·Recruiting·Listed Jan 2022

Apply to this trial

Interactive Computer-adaptive Chronic Kidney Disease Education Program

for Chronic Kidney Diseases

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18 - 70

Code: NCT06364358·Recruiting·Listed Apr 2024

Apply to this trial

Melanated Group Midwifery Care (MGMC)

for Pregnancy Complications

1 location in Chicago

Sponsor: University of Illinois at Chicago

Sex: Female·Age: 15 - 49·Accepts healthy volunteers

Code: NCT05365815·Recruiting·Listed May 2022

Apply to this trial

Remote Evaluation of MIND Diet

for Multiple Sclerosis

1 location in Urbana

Sponsor: University of Illinois at Urbana-Champaign

Sex: All·Age: 18 - 64

Code: NCT06450977·Recruiting·Listed Jun 2024

Apply to this trial

Pharmacological Inhibition of Lactation After 16 to 20 Week Abortion

for Lactation Suppressed

1 location in Chicago

Sponsor: Northwestern University

Sex: Female·Age: 18 - 50·Accepts healthy volunteers

Code: NCT06123026·Phase 4·Recruiting·Listed Nov 2023

Apply to this trial

Intra-articular Platelet-Rich Plasma Compared With Viscosupplementation in the Treatment of Knee Osteoarthritis

for Knee Osteoarthritis

1 location in Skokie

Sponsor: Endeavor Health

Sex: All·Age: 18 - 75

Code: NCT03491761·Phase 2·Recruiting·Listed Apr 2018

Apply to this trial

Intra-operative Loop Diuretics to Improve Same-day Discharge Rates After HoLEP

for BPH With Urinary Obstruction

1 location in Chicago

Sponsor: Northwestern University

Sex: Male·Age: 18 - 89·Accepts healthy volunteers

Code: NCT05620784·Phase 3·Recruiting·Listed Nov 2022

Apply to this trial

Immunogenicity of Zoster Vaccine in Allogeneic Hematopoietic Stem Cell Transplant Recipients

for Shingles

1 location in Maywood

Sponsor: Loyola University

Sex: All·Age: All ages

Code: NCT05554068·Phase 2·Recruiting·Listed Sep 2022

Apply to this trial

I3LUNG: Integrative Science, Intelligent Data Platform for Individualized LUNG Cancer Care With Immunotherapy

for Non Small Cell Lung Cancer

1 location in Chicago

Sponsor: Fondazione IRCCS Istituto Nazionale dei Tumori, Milano

Sex: All·Age: 18+

Code: NCT05537922·Recruiting·Listed Sep 2022

Apply to this trial

Convalescent Plasma as a Possible Treatment for COVID-19

for COVID-19

1 location in Chicago

Sponsor: University of Illinois at Chicago

Sex: All·Age: 40+

Code: NCT04442191·Phase 2·Recruiting·Listed Jun 2020

Apply to this trial

AMBITION 7: A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Insulin Glargine in People With Type 2 Diabetes and Increased Risk of Diseases That Affect the Heart and Blood Vessels Treated With 1-3 Other Diabetes Medications

for Type 2 Diabetes

Sites in Peoria, Hazel Crest +107 more locations

Sponsor: Novo Nordisk A/S

Sex: All·Age: 45+

Code: NCT07797335·Phase 3·Recruiting·Listed Sep 1, 2026

Apply to this trial

BRIDGE & Friends Trial

for Obesity & Overweight

1 location in Chicago

Sponsor: University of Illinois at Chicago

Sex: All·Age: 50 - 79·Accepts healthy volunteers

Code: NCT07798557·Recruiting·Listed Sep 1, 2026

Apply to this trial

A Study of EDG-15400 in Adults With Heart Failure With Preserved Ejection Fraction (EQUINOX-HFpEF)

for Heart Failure With Preserved Ejection Fraction

Sites in Peoria +24 more locations

Sponsor: Edgewise Therapeutics, Inc.

Sex: All·Age: 30 - 84

Code: NCT07795814·Phase 2·Recruiting·Listed Aug 31, 2026

Apply to this trial

The Effects of the Melillo Method® on Biopsychosocial Outcomes in School-Age Children

for Social Behavior Disorders

1 location in Roodhouse

Sponsor: Life University

Sex: All·Age: 8+

Code: NCT07779889·Recruiting·Listed Aug 21, 2026

Apply to this trial

Alcohol, Breast Cancer, and Metabolism

for Alcohol Drinking

1 location in Urbana

Sponsor: University of Illinois at Urbana-Champaign

Sex: Female·Age: 21 - 45·Accepts healthy volunteers

Code: NCT07779967·Recruiting·Listed Aug 21, 2026

Apply to this trial

Non-Invasive Neurofeedback Training to Alleviate Tinnitus Distress

for Tinnitus Aggravated

1 location in Urbana

Sponsor: University of Illinois at Urbana-Champaign

Sex: All·Age: 18 - 70

Code: NCT07788638·Recruiting·Listed Aug 26, 2026

Apply to this trial

A Study to Evaluate Effect of AZD6234 as an Adjunct to Incretin-based Therapies in Adult Participants With Obesity or Overweight With Weight-related Comorbidity With or Without Type 2 Diabetes Mellitus

for Obesity or Overweight

Sites in Chicago, Champaign +19 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07776509·Phase 3·Recruiting·Listed Aug 20, 2026

Apply to this trial

A Study to Evaluate Effect of AZD6234 in Adult Participants With Obesity or Overweight With Weight-related Comorbidity Without Type 2 Diabetes Mellitus

for Obesity or Overweight

Sites in Chicago, Champaign +30 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07784725·Phase 3·Recruiting·Listed Aug 25, 2026

Apply to this trial

A Study to Evaluate the Efficacy and Safety of Subcutaneous Nomlabofusp in Subjects With Friedreich's Ataxia

for Friedreich Ataxia

Sites in Chicago +2 more locations

Sponsor: Larimar Therapeutics, Inc.

Sex: All·Age: 12 - 40

Code: NCT07778836·Phase 3·Recruiting·Listed Aug 21, 2026

Apply to this trial

A Study of the Long-term Safety and Efficacy of Danicamtiv in Adults With Symptomatic Genetic and Familial Dilated Cardiomyopathy

for Symptomatic Genetic Dilated Cardiomyopathy (DCM)

Sites in Chicago +27 more locations

Sponsor: Kardigan, Inc.

Sex: All·Age: 18+

Code: NCT07771465·Phase 3·Recruiting·Listed Aug 18, 2026

Apply to this trial

Studying NMDA and Sigma-1 in Smoking Cessation Treatment (SUMMIT)

for Smoking Cessation

Sites in Skokie +15 more locations

Sponsor: Axsome Therapeutics, Inc.

Sex: All·Age: 18 - 65

Code: NCT07766655·Phase 3·Recruiting·Listed Aug 14, 2026

Apply to this trial

Central Auditory Processing Modulation Underlying Anxiety Reduction Using Clinically Designed Improvisatory Music

for Alzheimer's Disease

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 55+

Code: NCT07775625·Recruiting·Listed Aug 20, 2026

Apply to this trial

Severe Complications During Ventricular Tachycardia or Premature Ventricular Complex Ablation

for Ventricular Tachycardia (VT)

Sites in Chicago +1 more location

Sponsor: University Hospital, Basel, Switzerland

Sex: All·Age: 18+

Code: NCT07777744·Recruiting·Listed Aug 20, 2026

Apply to this trial