Paid Clinical Trials in Illinois

Illinois has 2,847 paid clinical trials enrolling now across cities including Chicago, Peoria and Evanston. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Illinois include Northwestern Medicine, University of Chicago Medicine and Rush, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 14, 2026.

Filter results

Filter results

State

City

Recruitment status

Phase

Study type

Intervention

Condition

Sex

Age

Healthy volunteers only

2,519 clinical trials

Get a weekly email when new trials open in Chicago, IL.

A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF

for Heart Failure With Preserved Ejection Fraction (HFpEF)

Sites in Chicago, Rockford +105 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07761117·Phase 3·Recruiting·Listed Aug 12, 2026

Apply to this trial

Pain Control With Ketorolac and Nerve Block After Wrist and Hand Surgery

for Surgery, Upper Extremity

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT07773155·Phase 4·Recruiting·Listed Aug 19, 2026

Apply to this trial

A Study to Investigate Outcomes With Elecoglipron Compared With Placebo in Adult Participants With Chronic Kidney Disease.

for Chronic Kidney Disease

Sites in Chicago, Rockford +109 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07753993·Phase 3·Recruiting·Listed Aug 10, 2026

Apply to this trial

Microbiome Determinants of Adverse Effects of Stereotactic Radiosurgery

for Adverse Radiation Effects

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT07767981·Recruiting·Listed Aug 17, 2026

Apply to this trial

A Study to Test Whether Survodutide Helps People With Type 2 Diabetes Control Their Blood Sugar

for Type 2 Diabetes

Drug: Survodutide

Sites in Skokie +88 more locations

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT07754461·Phase 3·Recruiting·Listed Aug 10, 2026

Apply to this trial

Non-invasive Prediction of EArly Cardiac rEjection

for Heart Transplant

Sites in Chicago +21 more locations

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 6 - 25

Code: NCT07770659·Recruiting·Listed Aug 18, 2026

Apply to this trial

A Study of the Safety and Efficacy of Prime Editing (PM577) in Participants With Wilson Disease (WD)

for Wilson Disease

Sites in Chicago +1 more location

Sponsor: Prime Medicine, Inc.

Sex: All·Age: 12+

Code: NCT07748403·Phase 1, Phase 2·Recruiting·Listed Aug 5, 2026

Apply to this trial

Recovery Legal Care Randomized Trial

for Firearm Injury

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 14+

Code: NCT07764458·Recruiting·Listed Aug 14, 2026

Apply to this trial

Study of AZD0120 in Newly Diagnosed Multiple Myeloma Ineligible for ASCT

for Newly Diagnosed Multiple Myeloma

Sites in Chicago +43 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07764978·Phase 3·Recruiting·Listed Aug 14, 2026

Apply to this trial

A Research Study to Compare Two Different Versions of Injectable Cagrilintide and Placebo in People With Excess Body Weight

for Overweight

Sites in Oak Park +10 more locations

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07745504·Phase 3·Recruiting·Listed Aug 4, 2026

Apply to this trial

Tempus Open Link for Individual Voices in Innovative Analytics Registry: Platform Protocol for Multimodal Real-World Evidence in Cancer

for Cancer

1 location in Chicago

Sponsor: Tempus AI

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT07756034·Recruiting·Listed Aug 10, 2026

Apply to this trial

A Study in Young People and Adults to Learn About the Medicine Ritlecitinib for Treatment of Patchy Hair Loss, Known by the Medical Term as Moderate Alopecia Areata

for Alopecia Areata

Drug: Ritlecitinib

Sites in Skokie +16 more locations

Sponsor: Pfizer

Sex: All·Age: 12+

Code: NCT07733765·Phase 3·Recruiting·Listed Jul 29, 2026

Apply to this trial

Medication Collaboration Feasibility Study

for Dementia Family Caregiver

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 60+

Code: NCT07742189·Recruiting·Listed Aug 3, 2026

Apply to this trial

Healthy Options At Pantries (HOAP) Study

for Food Choice

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07729436·Recruiting·Listed Jul 27, 2026

Apply to this trial

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes

for Obesity

Sites in Schaumburg +84 more locations

Sponsor: Ascletis Pharma (China) Co., Limited

Sex: All·Age: 18+

Code: NCT07743450·Phase 3·Recruiting·Listed Aug 3, 2026

Apply to this trial

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities

for Obesity

Sites in Schaumburg +66 more locations

Sponsor: Ascletis Pharma (China) Co., Limited

Sex: All·Age: 18+

Code: NCT07743463·Phase 3·Recruiting·Listed Aug 3, 2026

Apply to this trial

Aromatherapy and Music Impact on Nurses' Stress at Work

for Stress

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07732179·Recruiting·Listed Jul 28, 2026

Apply to this trial

A Study to Investigate the Efficacy and Safety of Apraglutide Compared With Placebo in Adult Participants With Short Bowel Syndrome Associated With Intestinal Failure (SBS-IF)

for Short Bowel Syndrome (SBS)

Sites in Maywood +16 more locations

Sponsor: VectivBio AG

Sex: All·Age: 18+

Code: NCT07742735·Phase 3·Recruiting·Listed Aug 3, 2026

Apply to this trial

A Study of Esketamine Nasal Spray Versus Placebo Spray in Adult Participants With Treatment-resistant Depression

for Depressive Disorder, Treatment-Resistant

Sites in Skokie +2 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07716098·Phase 3·Recruiting·Listed Jul 21, 2026

Apply to this trial

A Study to Assess the Safety, Tolerability and How Single Ascending Doses of ABBV-859 Moves Through the Body of Healthy Adult Participants

for Healthy Volunteer

Sites in Grayslake +1 more location

Sponsor: AbbVie

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07736638·Phase 1·Recruiting·Listed Jul 30, 2026

Apply to this trial

Dose Optimization Study of Acute Intermittent Hypoxia in Spinal Cord Injury

for Spinal Cord Injuries (SCI)

1 location in Chicago

Sponsor: Milap Sandhu

Sex: All·Age: 18 - 75

Code: NCT07739992·Recruiting·Listed Jul 31, 2026

Apply to this trial

Phase 1/2 Study of Respiratory Syncytial Virus and Human Metapneumovirus (RSV+HMPV) Vaccine Candidate in Adults 60 Years of Age and Older

for Respiratory Syncytial Virus Immunization

Sites in Melrose Park +16 more locations

Sponsor: Sanofi

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT07734649·Phase 1, Phase 2·Recruiting·Listed Jul 29, 2026

Apply to this trial

Study of Advanced Therapies for the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease or Ulcerative Colitis

for Crohn's Disease

Sites in Oak Lawn +25 more locations

Sponsor: AbbVie

Sex: All·Age: 18 - 75

Code: NCT07697456·Phase 2·Recruiting·Listed Jul 2026

Apply to this trial

Retinal Fundus Imaging and OCT Imaging for Ocular Detection of ATTR-CM

for Transthyretin Amyloid Cardiomyopathy

Sites in Chicago +5 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07690436·Recruiting·Listed Jul 2026

Apply to this trial

Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)

for Obesity

Sites in Chicago, Skokie +68 more locations

Sponsor: Amgen

Sex: All·Age: 18 - 99

Code: NCT07684235·Phase 3·Recruiting·Listed Jul 2026

Apply to this trial

DRAGON Registry - International Multicenter Registry and Medical Image Bank for Patients With Primarily Unresectable Liver Cancer or Liver Metastases That Underwent Combined Portal and Hepatic Vein Embolization (PVE/HVE) to Increase Future Liver Remnant Before Resection.

for Liver Cancer

Sites in Chicago +2 more locations

Sponsor: Maastricht University Medical Center

Sex: All·Age: 18+

Code: NCT07717437·Recruiting·Listed Jul 21, 2026

Apply to this trial

Transition Care for FEP

for Schizoaffective Disorders

1 location in Harvey

Sponsor: University of Chicago

Sex: All·Age: 18 - 40

Code: NCT07713849·Recruiting·Listed Jul 20, 2026

Apply to this trial

Consumer Evaluation of an Investigational Intermittent Catheter

for Urinary Retention

1 location in Libertyville

Sponsor: Hollister Incorporated

Sex: Male·Age: 22+

Code: NCT07714694·Recruiting·Listed Jul 20, 2026

Apply to this trial

Optimizing Sustainable Cuff Access and Training Pathways for Self-Measured Blood Pressure Monitoring in Primary Care

for Hypertension

Sites in Chicago, Oak Lawn & Merrionette Park

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT07693699·Recruiting·Listed Jul 2026

Apply to this trial

Ocrevus Zunovo for MS: Mixed Methods

for Multiple Sclerosis

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT07710105·Recruiting·Listed Jul 2026

Apply to this trial

A Phase 3 Study of Rezpegaldesleukin (NKTR-358) for Patients ≥ 12 Years of Age With Moderate-to-Severe Atopic Dermatitis

for Moderate-to-Severe Atopic Dermatitis

Sites in Normal +11 more locations

Sponsor: Nektar Therapeutics

Sex: All·Age: 12+

Code: NCT07690371·Phase 3·Recruiting·Listed Jul 2026

Apply to this trial

A Multi-Site Study to Assess the Effect of Availability of a Heated Tobacco Product on Smoking Abstinence Among Current Primary Cigarette Smokers

for Smoking

Sites in Aurora, Gurnee +7 more locations

Sponsor: RAI Services Company

Sex: All·Age: 21 - 65·Accepts healthy volunteers

Code: NCT07710820·Recruiting·Listed Jul 2026

Apply to this trial

A Long-Term Safety Study of Elismetrep (K-304) in the Acute Treatment of Migraine

for Acute Migraine

Drug: Elismetrep

Sites in Chicago, Naperville +111 more locations

Sponsor: Kallyope Inc.

Sex: All·Age: 18+

Code: NCT07674654·Phase 3·Recruiting·Listed Jun 2026

Apply to this trial

Study to Assess How Different Oral Formulations of Ubrogepant Move Through the Body in Healthy Adult Participants

for Healthy Volunteer

Drug: Ubrogepant

1 location in Grayslake

Sponsor: AbbVie

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT07680686·Phase 1·Recruiting·Listed Jul 2026

Apply to this trial

A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DM

for Weight Management

Sites in Melrose Park +54 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07667803·Phase 3·Recruiting·Listed Jun 2026

Apply to this trial

Liver Transplantation From Donors With HIV: Impact on Opportunistic Infections, Cancer, and Long-Term Outcomes (Expanding HOPE Liver)

for HIV

Sites in Chicago +18 more locations

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT07665372·Recruiting·Listed Jun 2026

Apply to this trial

An Extension Study to Assess Safety and Efficacy of Remibrutinib in Participants With Moderate to Severe HS

for Hidradenitis Suppurativa

Drug: Remibrutinib

Sites in Glenview, West Dundee +11 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100

Code: NCT07665437·Phase 3·Recruiting·Listed Jun 2026

Apply to this trial

Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG).

for Diffuse Intrinsic Pontine Glioma

Sites in Chicago +5 more locations

Sponsor: BrainChild Bio, Inc

Sex: All·Age: 1 - 26

Code: NCT07680439·Phase 2·Recruiting·Listed Jul 2026

Apply to this trial

A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus and Impaired Renal Function on Background Dapagliflozin

for Type 2 Diabetes Mellitus

Drug: Dapagliflozin

Sites in Chicago +29 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07662135·Phase 3·Recruiting·Listed Jun 2026

Apply to this trial

A Phase III Study to Investigate the Efficacy and Safety of the Combination of Elecoglipron and Dapagliflozin in Adults With Type 2 Diabetes Mellitus

for Type 2 Diabetes Mellitus

Drug: Dapagliflozin

Sites in Chicago, Skokie +37 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07662109·Phase 3·Recruiting·Listed Jun 2026

Apply to this trial