Breast oncology Clinical Trials in Indianapolis, IN
As of August 2026, 23 paid clinical trials are recruiting for Breast oncology in Indianapolis, Indiana. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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23 clinical trials for Breast oncology
·Clear filters·A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer
A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer
Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread
A Study of LY4337713 in Participants With FAP-Positive Solid Tumors
A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors
A Study of LY4175408 in Participants With Advanced Cancer
Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma and Other Solid Tumors, Receiving Intravenous Infusion of Azirkitug Alone or in Combination(s) With Budigalimab, Bevacizumab, or Telisotuzumab Adizutecan
Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors
First-in-Human Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, as a Single Agent in Patients With Advanced Solid Tumors and in Combination With Endocrine Therapy +/- a CDK4/6 or CDK4 Inhibitor in Patients With Advanced Solid Tumors or Advanced Breast Cancer
A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
Low Dose Aspirin for the Prevention of Postpartum Related Breast Cancer
SOC Chemotherapy +/- Tocilizumab for Triple Negative and ER-low Breast Cancers
Avelumab or Hydroxychloroquine With or Without Palbociclib to Eliminate Dormant Breast Cancer
Exercise in Metastatic Breast Cancer: EMBody
HER2 Vaccine for Locally Advanced Breast Cancer
A Study of Tetrathiomolybdate (TM) Plus Capecitabine
NearWave Optical Molecular Monitoring
A Phase 1/2 Clinical Trial to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of HMBD-501 in Patients With HER3-Expressing Solid Tumors
Top Research Study Locations in Indianapolis
Researchers run research studies in Indianapolis, IN at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Indiana University | Alzheimer Disease, Amyotrophic Lateral Sclerosis, Dementia | 103 |
| Riley Hospital for Children | Malignant Solid Neoplasm, Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia | 63 |
| Indiana University School of Medicine | Dementia, Alzheimers Disease, Alzheimers Disease, Familial | 51 |
| Indiana University/Melvin and Bren Simon Cancer Center | Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, Stage IV Lung Cancer AJCC v8 | 33 |
| Indiana University Melvin and Bren Simon Comprehensive Cancer Center | Small Cell Lung Cancer, Germ Cell Tumor, Prostate Cancer | 28 |
| Indiana University Health | Myasthenia Gravis, Acetabulum Fractures, Acute Ischemic Stroke | 21 |
| Community Health Network | Colorectal Cancer, Pancreatic Ductal Adenocarcinoma, Head and Neck Squamous Cell Carcinoma | 20 |
| Indiana University Health University Hospital | Eosinophilic Esophagitis, Gastroparesis, Obesity or Overweight | 20 |
| Saint Catherine Hospital | Anatomic Stage II Breast Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8, Advanced Esophageal Adenocarcinoma | 20 |
| Indiana University Hospital | Gastroparesis, Abnormal Uterine Bleeding, Achalasia | 17 |
| IU Health Methodist Hospital | Coronary Artery Disease, Atrial Fibrillation, Breast Implant; Complications | 15 |
| Ascension Saint Vincent Indianapolis Hospital | Acute Myeloid Leukemia, Malignant Solid Neoplasm, Mixed Phenotype Acute Leukemia | 14 |
| Dawes Fretzin Clinical Research Group, LLC | Atopic Dermatitis, Eczema, Plaque Psoriasis | 14 |
| Richard L. Roudebush VA Medical Center, Indianapolis, IN | Prostate Cancer, Actinic Keratosis, Anxiety | 14 |
| Sidney and Lois Eskenazi Hospital | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8 | 13 |
| Riley Children's Hospital | Becker Muscular Dystrophy, Bowel Incontinence, CLOVES Syndrome | 12 |
| Franciscan Health | Neoplasm Metastasis, Carcinoma, Non-Small-Cell Lung, Colorectal Neoplasms | 11 |
| Franciscan Health Indianapolis | Anatomic Stage IV Breast Cancer AJCC v8, Breast Cancer, Cardiotoxicity | 11 |
| Indiana University Health Methodist Hospital | Diabetic Foot Ulcer (DFU), Acute Ischemic Stroke, Atherosclerotic Cardiovascular Disease (ASCVD) | 10 |
| IU Health University Hospital | Colitis, Ulcerative, Contraception, Crohn Disease | 9 |
| Ascension St. Vincent | Coronary Artery Disease, Aortic Valve Disease, Aortic Valve Stenosis | 8 |
| Indiana University Melvin and Bren Simon Cancer Center | Neoplasm Metastasis, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung | 8 |
| Riley Hospital for Children at Indiana University Health | ADHD - Attention Deficit Disorder With Hyperactivity, Anxiety Disorders, Aortic Coarctation | 8 |
| Midwest Inst For Clin Res | Obesity, Overweight, Diabetes Mellitus, Type 2 | 7 |
| Eskenazi Health | Hypertension, Aerobic Exercise, Alzheimer's Disease (Incl Subtypes) | 6 |
Active & Upcoming Studies in Indianapolis (2026)
Recruiting trials in Indianapolis grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (227 active studies)
- ImmuNe ParameTERs to Predict Immunotherapy REsponse and Toxicity (INTERPRET) · Indiana University
- Therapeutic Induction of Dermal Remodeling in Veterans to Prevent Actinic Neoplasia Caused by Chronic Environmental Exposure to Ultraviolet Radiation · VA Office of Research and Development
Cardiovascular (68 active studies)
- Utilizing Carbon Dioxide for Assessing Coronary Blood Flow in Subjects With Coronary Artery Disease · Indiana University
- LOw DosE Spironolactone, chlorThAlidone oR Combination in CKD Trial · Phase 2 · VA Office of Research and Development
Diabetes & metabolic (53 active studies)
- Effect Of Percutaneous Electrical Nerve Field Stimulation on Symptom Control/Nervous System Activity in Patients w/Diabetes Types 1/2 · Indiana University
- A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event · Phase 2 · Eli Lilly and Company
Neurology & pain (48 active studies)
- Overground Virtual Reality (VR) Gait Rehabilitation for Stroke · Indiana University
- VICA: A Virtual Care Assistant for Dementia Caregivers · Indiana University
Mental health & behavior (23 active studies)
- Improving Mental Healthcare Outcomes for Minoritized Veterans Through a Peer-led, Patient Navigation Program (PARTNER-MH 2.0) · VA Office of Research and Development
- Psilocybin Assisted Psychotherapy for Treatment Resistant Depression and Co-occurring Substance Use Disorder · Phase 1, Phase 2 · Indiana University
Pediatric (14 active studies)
HIV / STI (5 active studies)
- A Study to Evaluate the Use of Resmetirom in Participants With MASLD and HIV · Phase 2 · Naga P. Chalasani
- The Effects of Cognitive Behavioral Therapy on Insulin Resistance in People With HIV · Indiana University
Eye & vision (5 active studies)
- An Exploratory Efficacy and Safety Study of DFL24498 Topical Ophthalmic Solution Compared With Vehicle in Participants With Dry Eye Disease · Phase 2 · Dompé Farmaceutici S.p.A
- A Phase 2, Randomized, Placebo Controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL 3007 in Combination With Syfovre/Pegcetacoplan (APL-2) in Patients Diagnosed With Geographic Atrophy Secondary to Age Related Macular Degeneratio · Phase 2 · Apellis Pharmaceuticals, Inc.
Vaccines (1 active study)
- Azithromycin Treatment for Respiratory Syncytial Virus-induced Respiratory Failure in Children · Phase 3 · University of Alabama at Birmingham
Common conditions studied in Indianapolis
- Obesity (17 active studies)
- Heart Failure (14 active studies)
- Prostate Cancer (11 active studies)
- Dementia (10 active studies)
- Multiple Myeloma (10 active studies)
- Coronary Artery Disease (9 active studies)
Leading research sponsors in Indianapolis
- Indiana University
- Eli Lilly and Company
- National Cancer Institute (NCI)
- Children's Oncology Group
- Janssen Research & Development, LLC
Frequently asked questions
How many paid clinical trials are currently recruiting in Indianapolis?
There are approximately 878 recruiting clinical trials in Indianapolis, Indiana listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Indianapolis pay participants?
Most recruiting trials in Indianapolis compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Indianapolis?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Indianapolis?
The most common conditions under active study in Indianapolis include Obesity (17), Heart Failure (14), Prostate Cancer (11), Dementia (10), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Indianapolis?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Indianapolis on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Indianapolis?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Indianapolis?
Recruiting research sites in Indianapolis include Indiana University, Riley Hospital for Children, Indiana University School of Medicine, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Indianapolis right now?
The largest active categories in Indianapolis are Cancer & tumors (227), Cardiovascular (68), Diabetes & metabolic (53). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.