A Study of Brenipatide in Participants With Opioid Use Disorder
for Opioid Use Disorder
Drug: Brenipatide
Sites in Lexington +37 more locations
Sponsor: Eli Lilly and Company
Sex: All·Age: 18 - 75
Code: NCT07420283·Phase 2·Recruiting·Listed Feb 2026
Clinical Trials at University of Kentucky Chandler Medical Center
As of September 2026, 12 paid clinical trials are recruiting at University of Kentucky Chandler Medical Center, located at 740 S LIMESTONE, LEXINGTON, KY 40536-0001, phone (859) 323-8082 in Lexington, Kentucky. Active studies at this site cover conditions such as Heart Failure, Acute Myeloid Leukemia and Breast Cancer. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Filter results
Filter results
12 clinical trials at University of Kentucky Chandler Medical Center
·Clear filters· Get a weekly email when new trials open in Lexington, KY.
A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)
for Non-small Cell Lung Cancer (NSCLC)
Drug: Durvalumab
Sites in Lexington +36 more locations
Sponsor: Bristol-Myers Squibb
Sex: All·Age: 18+
Code: NCT07361497·Phase 3·Recruiting·Listed Jan 2026
A Study of Imlunestrant (LY3484356) in Premenopausal Women With Estrogen Receptor-Positive (ER+) Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Early Breast Cancer
for Breast Neoplasms
Sites in Lexington +33 more locations
Sponsor: Eli Lilly and Company
Sex: Female·Age: 18+
Code: NCT07287098·Phase 2·Recruiting·Listed Dec 2025
A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer
for Ovarian Neoplasms
Sites in Lexington, Louisville +86 more locations
Sponsor: Eli Lilly and Company
Sex: All·Age: 18+
Code: NCT07213804·Phase 3·Recruiting·Listed Oct 2025
Study to Assess Adverse Events and Disease Activity of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Children and Adolescents (Ages 6-17)
for Migraine
Drug: Ubrogepant
Sites in Lexington +85 more locations
Sponsor: AbbVie
Sex: All·Age: 6 - 17
Code: NCT05125302·Phase 3·Recruiting·Listed Nov 2021
A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
for Carcinoma, Non-Small-Cell Lung
Drug: LY3537982
Sites in Lexington +87 more locations
Sponsor: Eli Lilly and Company
Sex: All·Age: 18+
Code: NCT06119581·Phase 3·Recruiting·Listed Nov 2023
A Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (rrDLBCL) (MK-2140-003)
for DLBCL
Sites in Lexington, Edgewood +15 more locations
Sponsor: Merck Sharp & Dohme LLC
Sex: All·Age: 18+
Code: NCT05139017·Phase 2, Phase 3·Recruiting·Listed Dec 2021
Phase 2/3 Trial of Izalontamab Brengitecan vs Platinum-based Chemotherapy for Metastatic Urothelial Cancer With Disease Progression on or After Immunotherapy
for Urothelial Cancer
Sites in Lexington +32 more locations
Sponsor: Bristol-Myers Squibb
Sex: All·Age: 18+
Code: NCT07106762·Phase 2, Phase 3·Recruiting·Listed Aug 2025
A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)
for Prostate Cancer
Sites in Lexington +49 more locations
Sponsor: Merck Sharp & Dohme LLC
Sex: Male·Age: 18+
Code: NCT06925737·Phase 3·Recruiting·Listed Apr 2025
A Study to Compare the Combination of Navlimetostat (BMS-986504) With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion
for Metastatic Non-small Cell Lung Cancer With MTAP Deletion
Drug: Navlimetostat
Sites in Lexington +33 more locations
Sponsor: Bristol-Myers Squibb
Sex: All·Age: 18+
Code: NCT07063745·Phase 2, Phase 3·Recruiting·Listed Jul 2025
Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease
for Crohn's Disease
Sites in Lexington +55 more locations
Sponsor: AbbVie
Sex: All·Age: 18 - 75
Code: NCT06548542·Phase 2·Recruiting·Listed Aug 2024
Clinical Trial Evaluating the Safety, Tolerability and Preliminary Efficacy of BNT116 Alone and in Combinations in Patients With Advanced Non-small Cell Lung Cancer
for Non-Small Cell Lung Cancer
Sites in Lexington, Louisville +4 more locations
Sponsor: BioNTech SE
Sex: All·Age: 18+
Code: NCT05142189·Phase 1·Recruiting·Listed Dec 2021
Common conditions studied in Lexington
- Heart Failure (10 active studies)
- Acute Myeloid Leukemia (8 active studies)
- Breast Cancer (8 active studies)
- Obesity (8 active studies)
- Ovarian Cancer (8 active studies)
- Malignant Solid Neoplasm (7 active studies)
Leading research sponsors in Lexington
- National Cancer Institute (NCI)
- SWOG Cancer Research Network
- NRG Oncology
- Children's Oncology Group
- AstraZeneca
Frequently asked questions
How many paid clinical trials are currently recruiting in Lexington?
There are approximately 460 recruiting clinical trials in Lexington, Kentucky listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Lexington pay participants?
Most recruiting trials in Lexington compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Lexington?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Lexington?
The most common conditions under active study in Lexington include Heart Failure (10), Acute Myeloid Leukemia (8), Breast Cancer (8), Obesity (8), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Lexington?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Lexington on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Lexington?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Lexington?
Recruiting research sites in Lexington include University of Kentucky, University of Kentucky/Markey Cancer Center, Baptist Health Lexington, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Lexington right now?
The largest active categories in Lexington are Cancer & tumors (177), Neurology & pain (32), Cardiovascular (31). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
What is the address of University of Kentucky Chandler Medical Center?
University of Kentucky Chandler Medical Center is located at 740 S LIMESTONE, LEXINGTON, KY 40536-0001. Use the Google Maps link in the intro above to get directions.
How do I contact University of Kentucky Chandler Medical Center?
You can reach University of Kentucky Chandler Medical Center by phone at (859) 323-8082. For questions about a specific trial, use the study coordinator contact listed on the individual study record — click any trial title above to open it.
Browse more clinical trials
Other cities in Kentucky
Louisville, KY(491)Edgewood, KY(50)Bardstown, KY(35)Bowling Green, KY(33)Owensboro, KY(31)Corbin, KY(29)Paducah, KY(27)London, KY(22)Mount Sterling, KY(20)Elizabethtown, KY(16)Ashland, KY(6)Crestview Hills, KY(6)Hazard, KY(5)Cynthiana, KY(4)Florence, KY(3)Frankfort, KY(3)Georgetown, KY(3)Maysville, KY(3)Morehead, KY(3)Murray, KY(3)Pikeville, KY(3)Winchester, KY(3)Campbellsville, KY(2)Covington, KY(2)Glasgow, KY(2)Mount Vernon, KY(2)Nicholasville, KY(2)Prospect, KY(2)Richmond, KY(2)Somerset, KY(2)Versailles, KY(2)Barbourville, KY(1)Danville, KY(1)Dyer, KY(1)Fort Thomas, KY(1)Greenville, KY(1)Hardinsburg, KY(1)Harlan, KY(1)Hartford, KY(1)Henderson, KY(1)Hopkinsville, KY(1)Hyden, KY(1)Lousiville, KY(1)Manchester, KY(1)Newport, KY(1)Pewee Valley, KY(1)Saint Matthews, KY(1)Shelbyville, KY(1)Whitesburg, KY(1)