Paid Clinical Trials in Little Rock, AR
As of July 2026, 497 paid clinical trials are recruiting in Little Rock, Arkansas. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Little Rock offers studies at sites including University of Arkansas for Medical Sciences for conditions such as Schizophrenia, Acute Myeloid Leukemia, Duchenne Muscular Dystrophy, Endometrial Cancer. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Little Rock
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Researchers run research studies in Little Rock, AR at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Arkansas for Medical Sciences | Acute Myeloid Leukemia, Stage IV Lung Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 106 |
| Arkansas Children's Hospital | Duchenne Muscular Dystrophy, Neuroblastoma, Acute Myeloid Leukemia | 91 |
| CARTI Cancer Center | Malignant Solid Neoplasm, Hematopoietic and Lymphatic System Neoplasm, Plasma Cell Myeloma | 30 |
| Arkansas Urology | Non-muscle Invasive Bladder Cancer With Carcinoma in Situ, Benign Prostatic Hyperplasia, Bladder (Urothelial, Transitional Cell) Cancer | 13 |
| Woodland International Research Group | Alcohol Use Disorder, Bipolar Depression, Bipolar Disorder | 12 |
| Applied Research Center of Arkansas | Thyroid Eye Disease, COVID-19 SARS-CoV-2 Infection, Clostridioides Difficile Associated Disease | 11 |
| Arkansas Children's Nutrition Center | Healthy, Adiposity, Blood Pressure | 10 |
| University of Arkansas | Breast Reconstruction, Cesarean Delivery, Diffuse Large B Cell Lymphoma (DLBCL) | 9 |
| Arkansas Children's Research Institute | Physical Activities, Duchene Muscular Dystrophy, High-grade Glioma | 8 |
| Arkansas Childrens Hospital | Contraception, Duchenne Muscular Dystrophy, Eosinophilic Esophagitis (EoE) | 6 |
| Pillar Clinical Research- Little Rock | Schizophrenia, Bipolar Disorder, Bipolar Disorder Type I With Mania | 6 |
| Arkansas Heart Hospital | Acute Myocardial Infarction, Aortic Valve Disease, Aortic Valve Stenosis | 5 |
| Pillar Clinical Research, LLC | Schizophrenia, Autism Spectrum Disorder, Bipolar Depression | 5 |
| Preferred Research Partners, Inc. | Attention-Deficit/Hyperactivity Disorder, Generalized Anxiety Disorder, Major Depressive Disorder | 5 |
| Arkansas Children's | B-Cell ALL, B-Cell Acute Lymphoblastic Leukaemia, B-Cell Lymphoblastic Leukemia | 4 |
| Arkansas Children's Hospital Research Institute | Adrenal Insufficiency, Arrythmia, Asthma in Children | 4 |
| Baptist Health Medical Center - Little Rock | Advanced Esophageal Adenocarcinoma, Advanced Gastric Adenocarcinoma, Advanced Gastroesophageal Junction Adenocarcinoma | 4 |
| Lynn Institute of the Ozarks | Cardiovascular Disease, Diabetic Peripheral Neuropathic Pain, Difficult to Control Hypertension | 4 |
| Neurocrine Clinical Site | Major Depressive Disorder, Schizophrenia | 4 |
| Arkansas Cardiology | Cryptogenic Stroke, Heart Failure With Mildly Reduced Ejection Fraction, Heart Failure With Preserved Ejection Fraction | 3 |
| Arkansas Children's Hospital Research Institute: Department of Pediatrics, Allergy & Immunology | Allergy, Alpha-Gal Syndrome, Peanut Allergy | 3 |
| Arkansas Clinical Research | Acute Migraine, Migraine, Obesity | 3 |
| Central Arkansas Veterans Healthcare System , Little Rock, AR | Carcinoma, Hepatocellular, Cirrhosis, Liver Diseases | 3 |
| Clinical Trials, Inc. | Focal Epilepsy, Focal Onset Seizures | 3 |
| Pillar Clinical Research | Schizophrenia, Bipolar I Disorder | 3 |
Active & Upcoming Studies in Little Rock (2026)
Recruiting trials in Little Rock grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (137 active studies)
- An Open-label Study to Investigate the Efficacy and Safety of Dato-DXd + Rilvegostomig vs SoC in Adult Participants With High-risk MIUC · Phase 3 · AstraZeneca
- MMulti-Immune HR; Multi-Target Immunotherapy for High-Risk Multiple Myeloma · Phase 2 · University of Arkansas
Mental health & behavior (39 active studies)
- Relapse Prevention Trial Evaluating KarXT Treatment in Schizophrenia · Phase 3 · Karuna Therapeutics, Inc., a Bristol Myers Squibb company
- A Study of LTX-001 In Adult Participants With Acute Exacerbation of Schizophrenia · Phase 1 · Leal Therapeutics, Inc
Cardiovascular (29 active studies)
- Rapid Inflation/Deflation Compared With Prolonged High-Pressure Balloon Inflation · Central Arkansas Veterans Healthcare System
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
Neurology & pain (27 active studies)
- A Long-Term Safety Study of Elismetrep (K-304) in the Acute Treatment of Migraine · Phase 3 · Kallyope Inc.
- A Study to Evaluate the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine · Phase 3 · Kallyope Inc.
Diabetes & metabolic (25 active studies)
- Effect Of Whole or Skimmed Milk Greek Yogurt on Integrated Muscle Protein Synthesis, Glucose Homeostasis, and Cognition in Post-Menopausal Women · University of Arkansas
- A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2) · Phase 3 · Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
Pediatric (12 active studies)
- Longitudinal Prospective Study of Maternal and Child Nutrition in Arkansas · Arkansas Children's Hospital Research Institute
- How Different Levels of CPAP Affect Oxygen Delivery and Lung Expansion in Preterm Infants · University of Arkansas
Vaccines (4 active studies)
- A Study on the Safety and Immune Response of Investigational mRNA Seasonal Flu/COVID-19 Combination Vaccine in Adults · Phase 1 · GlaxoSmithKline
- A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease · Phase 3 · Pfizer
HIV / STI (1 active study)
- Universal Basic Income and Structural Racism in the US South: HIV Care · University of Arkansas
Common conditions studied in Little Rock
- Schizophrenia (17 active studies)
- Acute Myeloid Leukemia (11 active studies)
- Duchenne Muscular Dystrophy (10 active studies)
- Endometrial Cancer (7 active studies)
- Malignant Solid Neoplasm (7 active studies)
- Obesity (7 active studies)
Leading research sponsors in Little Rock
- University of Arkansas
- National Cancer Institute (NCI)
- Arkansas Children's Hospital Research Institute
- Children's Oncology Group
- NRG Oncology
Frequently asked questions
How many paid clinical trials are currently recruiting in Little Rock?
There are approximately 497 recruiting clinical trials in Little Rock, Arkansas listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Little Rock pay participants?
Most recruiting trials in Little Rock compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Little Rock?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Little Rock?
The most common conditions under active study in Little Rock include Schizophrenia (17), Acute Myeloid Leukemia (11), Duchenne Muscular Dystrophy (10), Endometrial Cancer (7), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Little Rock?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Little Rock on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Little Rock?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Little Rock?
Recruiting research sites in Little Rock include University of Arkansas for Medical Sciences, Arkansas Children's Hospital, CARTI Cancer Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Little Rock right now?
The largest active categories in Little Rock are Cancer & tumors (137), Mental health & behavior (39), Cardiovascular (29). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.