A Study of ARC-02 in B-cell NHL
for B-cell Non Hodgkin Lymphoma
Sites in Louisville +6 more locations
Sponsor: Taiho Oncology, Inc.
Sex: All·Age: 18+
Code: NCT07691606·Phase 1·Recruiting·Listed Jul 9, 2026
Clinical Trials at Norton Cancer Institute
As of September 2026, 34 paid clinical trials are recruiting at Norton Cancer Institute, located at Norton Cancer Institute - Downtown, 676 S Floyd St, Louisville, KY 40202, phone (502) 629-2500 in Louisville, Kentucky. Active studies at this site cover conditions such as Obesity, Heart Failure and Overweight. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Louisville
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
35 clinical trials at Norton Cancer Institute
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A Study of Pasritamig With Docetaxel Versus Docetaxel in Participants With Metastatic Castration-Resistant Prostate Cancer
for Prostatic Neoplasms, Castration-Resistant
Drug: Pasritamig
Sites in Louisville, Edgewood +51 more locations
Sponsor: Janssen Research & Development, LLC
Sex: All·Age: 18+
Code: NCT07225946·Phase 3·Recruiting·Listed Nov 2025
A Study Comparing JNJ-79635322 and an Anti-B-cell Maturation Antigen (BCMA)xCD3 Bispecific Antibody in Participants With Relapsed or Refractory Multiple Myeloma
for Multiple Myeloma
Sites in Louisville +38 more locations
Sponsor: Janssen Research & Development, LLC
Sex: All·Age: 18+
Code: NCT07258511·Phase 3·Recruiting·Listed Dec 2025
A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer
for Metastatic Castration-resistant Prostate Cancer
Sites in Louisville +42 more locations
Sponsor: Amgen
Sex: Male·Age: 18+
Code: NCT07213674·Phase 3·Recruiting·Listed Oct 2025
Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL
for Large B-cell Lymphoma
Sites in Louisville, Lexington +59 more locations
Sponsor: Allogene Therapeutics
Sex: All·Age: 18+
Code: NCT06500273·Phase 2·Recruiting·Listed Jul 2024
A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)
for Leukemia, Myeloid, Acute
Drug: Venetoclax
Sites in Louisville, Lexington +54 more locations
Sponsor: Janssen Research & Development, LLC
Sex: All·Age: 18+
Code: NCT06852222·Phase 3·Recruiting·Listed Feb 2025
A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma
for Multiple Myeloma
Drug: Daratumumab
Sites in Louisville +65 more locations
Sponsor: Janssen Research & Development, LLC
Sex: All·Age: 18+
Code: NCT05552222·Phase 3·Recruiting·Listed Sep 2022
A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression
for Ovarian Cancer
Drug: INCB123667
Sites in Louisville +37 more locations
Sponsor: Incyte Corporation
Sex: Female·Age: 18 - 99
Code: NCT07023627·Phase 2·Recruiting·Listed Jun 2025
Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)
for Brain Tumor, Recurrent
Sites in Louisville +50 more locations
Sponsor: GT Medical Technologies, Inc.
Sex: All·Age: All ages
Code: NCT04427384·Recruiting·Listed Jun 2020
Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation
for Metastatic Breast Cancer
Sites in Louisville +30 more locations
Sponsor: LeonaBio
Sex: All·Age: 18+
Code: NCT05696626·Phase 3·Recruiting·Listed Jan 2023
Study of Navtemadlin add-on to Ruxolitinib in JAK Inhibitor-Naïve Patients With Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib
for Myelofibrosis
Drug: Ruxolitinib
Sites in Louisville +57 more locations
Sponsor: Kartos Therapeutics, Inc.
Sex: All·Age: 18+
Code: NCT06479135·Phase 3·Recruiting·Listed Jun 2024
A Study Comparing JNJ-79635322 and Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma
for Multiple Myeloma
Drug: Teclistamab
Sites in Louisville +34 more locations
Sponsor: Janssen Research & Development, LLC
Sex: All·Age: 18+
Code: NCT07518186·Phase 3·Recruiting·Listed Apr 2026
A Study to Compare Elritercept With Epoetin Alfa to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions
for Myelodysplastic Syndrome
Sites in Louisville +24 more locations
Sponsor: Takeda
Sex: All·Age: 18+
Code: NCT07422480·Phase 3·Recruiting·Listed Feb 2026
A Phase 1 Study of IM-1021 in Participants With Advanced Cancer
for Solid Malignancies
Sites in Louisville +18 more locations
Sponsor: Immunome, Inc.
Sex: All·Age: 18+
Code: NCT06823167·Phase 1·Recruiting·Listed Feb 2025
A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions
for Myelodysplastic Syndromes
Sites in Louisville +21 more locations
Sponsor: Takeda
Sex: All·Age: 18+
Code: NCT06499285·Phase 3·Recruiting·Listed Jul 2024
Safety and Tolerability Study of GIM-122 in Subjects With Advanced Solid Malignancies
for Advanced Solid Malignancies
Sites in Louisville +10 more locations
Sponsor: Georgiamune Inc
Sex: All·Age: 18+
Code: NCT06028074·Phase 1, Phase 2·Recruiting·Listed Sep 2023
A Study of ASP1002 in Adults for Treatment of Solid Tumors
for Advanced Solid Tumors
Sites in Louisville +11 more locations
Sponsor: Astellas Pharma Global Development, Inc.
Sex: All·Age: 18+
Code: NCT05719558·Phase 1·Recruiting·Listed Feb 2023
A Study to See if Giving Fianlimab and Cemiplimab Together is Better Than Cemiplimab Alone at Treating Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma
for Head and Neck Squamous Cell Carcinoma (HNSCC)
Drug: Cemiplimab
Sites in Louisville, Edgewood +16 more locations
Sponsor: Regeneron Pharmaceuticals
Sex: All·Age: 18+
Code: NCT06769698·Phase 2·Recruiting·Listed Jan 2025
A Clinical Trial Investigating the Safety, Tolerability, and Therapeutic Effects of BNT113 in Combination With Pembrolizumab Versus Pembrolizumab Alone for Patients With a Form of Head and Neck Cancer Positive for Human Papilloma Virus 16 and Expressing the Protein PD-L1
for Unresectable Head and Neck Squamous Cell Carcinoma
Sites in Louisville +13 more locations
Sponsor: BioNTech SE
Sex: All·Age: 18+
Code: NCT04534205·Phase 2, Phase 3·Recruiting·Listed Sep 2020
A Study of Talquetamab in Participants With Relapsed or Refractory Multiple Myeloma
for Hematological Malignancies
Drug: Talquetamab
Sites in Louisville +8 more locations
Sponsor: Janssen Research & Development, LLC
Sex: All·Age: 18+
Code: NCT04634552·Phase 2·Recruiting·Listed Nov 2020
Spevatamig (PT886) as Monotherapy or in Combination With Chemo and/or ICI, for the Treatment of Patients With Advanced Gastric, Gastroesophageal Junction, Pancreatic Ductal or Biliary Tract Carcinomas (the TWINPEAK Study)
for Gastric or Gastroesophageal Junction Adenocarcinoma
Sites in Louisville +9 more locations
Sponsor: Phanes Therapeutics
Sex: All·Age: 18+
Code: NCT05482893·Phase 1, Phase 2·Recruiting·Listed Aug 2022
To Evaluate Efficacy of Belinostat or Pralatrexate in Combination Against CHOP Alone in PTCL
for Peripheral T Cell Lymphoma
Sites in Louisville +8 more locations
Sponsor: Acrotech Biopharma Inc.
Sex: All·Age: 18+
Code: NCT06072131·Phase 3·Recruiting·Listed Oct 2023
A Window of Opportunity Trial to Learn if Linvoseltamab is Safe and Well Tolerated, and How Well it Works in Adult Participants With Recently Diagnosed Multiple Myeloma Who Have Not Already Received Treatment
for Multiple Myeloma
Drug: Linvoseltamab
Sites in Louisville +12 more locations
Sponsor: Regeneron Pharmaceuticals
Sex: All·Age: 18+
Code: NCT05828511·Phase 1, Phase 2·Recruiting·Listed Apr 2023
A Trial to Find Out if REGN4336 is Safe and How Well it Works Alone and in Combination With REGN5678 for Adult Participants With Advanced Prostate Cancer
for Metastatic Castration-resistant Prostate Cancer
Sites in Louisville +12 more locations
Sponsor: Regeneron Pharmaceuticals
Sex: Male·Age: 18+
Code: NCT05125016·Phase 1, Phase 2·Recruiting·Listed Nov 2021
The OPAL Study: AVM0703 for Treatment of Lymphoid Malignancies
for Lymphoid Malignancies
Sites in Louisville +10 more locations
Sponsor: AVM Biotechnology Inc
Sex: All·Age: 12 - 95
Code: NCT04329728·Phase 1, Phase 2·Recruiting·Listed Apr 2020
Phase 1/2 Study of Linvoseltamab in Adult Patients With Relapsed or Refractory Multiple Myeloma
for Multiple Myeloma
Drug: Linvoseltamab
Sites in Louisville +6 more locations
Sponsor: Regeneron Pharmaceuticals
Sex: All·Age: 18+
Code: NCT03761108·Phase 1, Phase 2·Recruiting·Listed Dec 2018
Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors
for Non Small Cell Lung Cancer
Sites in Louisville +23 more locations
Sponsor: SystImmune Inc.
Sex: All·Age: 18+
Code: NCT05983432·Phase 1·Recruiting·Listed Aug 2023
A Clinical Study of YL205 in Patients With Advanced Solid Tumors
for Advanced Solid Tumors
Sites in Louisville +10 more locations
Sponsor: MediLink Therapeutics (Suzhou) Co., Ltd.
Sex: All·Age: 18+
Code: NCT06459973·Phase 1, Phase 2·Recruiting·Listed Jun 2024
Evaluation of RBS2418 in Subjects With Advanced, Metastatic Solid Tumors
for Advanced Cancer
Drug: RBS2418
Sites in Louisville +11 more locations
Sponsor: Riboscience, LLC.
Sex: All·Age: 18+
Code: NCT05270213·Phase 1·Recruiting·Listed Mar 2022
Clinical Trial Evaluating the Safety, Tolerability and Preliminary Efficacy of BNT116 Alone and in Combinations in Patients With Advanced Non-small Cell Lung Cancer
for Non-Small Cell Lung Cancer
Sites in Louisville, Lexington +4 more locations
Sponsor: BioNTech SE
Sex: All·Age: 18+
Code: NCT05142189·Phase 1·Recruiting·Listed Dec 2021
A Study of ZW251 in Participants With Advanced Solid Tumors
for Hepatocellular Carcinoma
Sites in Louisville +7 more locations
Sponsor: Zymeworks BC Inc.
Sex: All·Age: 18+
Code: NCT07164313·Phase 1·Recruiting·Listed Sep 2025
A Trial to Study if REGN5837 in Combination With Odronextamab is Safe for Adult Participants With Aggressive B-cell Non-Hodgkin Lymphomas
for B-cell Non-Hodgkins Lymphoma (B-NHL)
Drug: Odronextamab
Sites in Louisville +8 more locations
Sponsor: Regeneron Pharmaceuticals
Sex: All·Age: 18+
Code: NCT05685173·Phase 1·Recruiting·Listed Jan 2023
TT-10 (PORT-6) and TT-4 (PORT-7) as Single Agents and in Combination in Subjects With Advanced Selected Solid Tumors
for Renal Cell Cancer
Sites in Louisville +2 more locations
Sponsor: Portage Biotech
Sex: All·Age: 18+
Code: NCT04969315·Phase 1, Phase 2·Recruiting·Listed Jul 2021
Assessment of Anti-tumor and Safety in Glumetinib in Patients With c-MET-positive Non-Small Cell Lung Cancer
for C-Met Exon 14 Mutation
2 locations in Louisville
Sponsor: Haihe Biopharma Co., Ltd.
Sex: All·Age: 18 - 80
Code: NCT04270591·Phase 1, Phase 2·Recruiting·Listed Feb 2020
Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)
for Solid Tumor
Drug: INBRX-106
Sites in Louisville +12 more locations
Sponsor: Inhibrx Biosciences, Inc
Sex: All·Age: 18+
Code: NCT04198766·Phase 1, Phase 2·Recruiting·Listed Dec 2019
Common conditions studied in Louisville
- Obesity (14 active studies)
- Heart Failure (12 active studies)
- Overweight (12 active studies)
- Acute Myeloid Leukemia (11 active studies)
- Breast Cancer (7 active studies)
- Gastroparesis (7 active studies)
Leading research sponsors in Louisville
- University of Louisville
- AstraZeneca
- National Cancer Institute (NCI)
- Children's Oncology Group
- Eli Lilly and Company
Frequently asked questions
How many paid clinical trials are currently recruiting in Louisville?
There are approximately 491 recruiting clinical trials in Louisville, Kentucky listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Louisville pay participants?
Most recruiting trials in Louisville compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Louisville?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Louisville?
The most common conditions under active study in Louisville include Obesity (14), Heart Failure (12), Overweight (12), Acute Myeloid Leukemia (11), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Louisville?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Louisville on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Louisville?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Louisville?
Recruiting research sites in Louisville include University of Louisville, Norton Cancer Institute, The James Graham Brown Cancer Center at University of Louisville, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Louisville right now?
The largest active categories in Louisville are Cancer & tumors (173), Cardiovascular (41), Diabetes & metabolic (36). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
What is the address of Norton Cancer Institute?
Norton Cancer Institute is located at Norton Cancer Institute - Downtown, 676 S Floyd St, Louisville, KY 40202. Use the Google Maps link in the intro above to get directions.
How do I contact Norton Cancer Institute?
You can reach Norton Cancer Institute by phone at (502) 629-2500. For questions about a specific trial, use the study coordinator contact listed on the individual study record — click any trial title above to open it.
Browse more clinical trials
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