Oncology Clinical Trials in Paducah, KY
As of September 2026, 14 paid clinical trials are recruiting for Oncology in Paducah, Kentucky. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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14 clinical trials for Oncology
·Clear filters·Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)
A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)
A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1%
Phase 3 Study of Gedatolisib as First-Line Treatment for Patients With HR-Positive, HER2-Negative Advanced Breast Cancer (VIKTORIA-2)
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
Cost Communication and Financial Navigation in Cancer Patients (COSTCOM)
A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer
Evaluating the Impact of Social and Genetic Factors on Outcomes in Adolescent and Young Adult Cancer Survivors
Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors
Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics
A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases
Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations
Top Research Study Locations in Paducah
Researchers run research studies in Paducah, KY at 13 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Mercy Health - Paducah Cancer Center | Lung Cancer Screening, Malignant Solid Neoplasm, Non-Hodgkin Lymphoma | 7 |
| Baptist Health Paducah | Ovarian Carcinoma, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 5 |
| Mercy Health - Paducah Medical Oncology and Hematology | Acral Lentiginous Melanoma, Anatomic Stage IV Breast Cancer AJCC v8, Clinical Stage IV Cutaneous Melanoma AJCC v8 | 2 |
| Mercy Health-Paducah Cancer Center | Breast Cancer, Hematologic Malignancies, Solid Tumors | 2 |
| CON-10079, Paducah, KY | Heart Failure | 1 |
| FIN-10079, Paducah, KY | Heart Failure | 1 |
| Local Institution - 0502 | Non-small Cell Lung Cancer | 1 |
| Mercy Health | Triple Negative Breast Cancer | 1 |
| Mercy Health-Paducah Medical Oncology and Hematology | Carcinoma, Non-Small-Cell Lung | 1 |
| Orthopaedic Institute of Western Kentucky | Degenerative Disc Disease, Spondylolisthesis | 1 |
| Paducah, KY Investigative | Acute Heart Failure, Heart Failure | 1 |
| Strenge Spine | Cervical Disc Disease | 1 |
| The Orthopaedic Institute | Degenerative Disc Disease(DDD) | 1 |
Active & Upcoming Studies in Paducah (2026)
Recruiting trials in Paducah grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (16 active studies)
- Phase 3 Study of Gedatolisib as First-Line Treatment for Patients With HR-Positive, HER2-Negative Advanced Breast Cancer (VIKTORIA-2) · Phase 3 · Celcuity Inc
- A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4) · Phase 3 · Mirati Therapeutics Inc.
Cardiovascular (4 active studies)
- Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin · Phase 3 · AstraZeneca
- A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients With Heart Failure Who Are Intolerant or Not Eligible for Treatment With Steroidal Mineralocorticoid Receptor Antagonists · Phase 3 · Colorado Prevention Center
Common conditions studied in Paducah
- Heart Failure (4 active studies)
- Breast Cancer (2 active studies)
- Lung Cancer Screening (2 active studies)
- Malignant Solid Neoplasm (2 active studies)
- Non-Hodgkin Lymphoma (2 active studies)
- Ovarian Carcinoma (2 active studies)
Leading research sponsors in Paducah
- SWOG Cancer Research Network
- AstraZeneca
- Colorado Prevention Center
- NRG Oncology
- ECOG-ACRIN Cancer Research Group
Frequently asked questions
How many paid clinical trials are currently recruiting in Paducah?
There are approximately 27 recruiting clinical trials in Paducah, Kentucky listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Paducah pay participants?
Most recruiting trials in Paducah compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Paducah?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Paducah?
The most common conditions under active study in Paducah include Heart Failure (4), Breast Cancer (2), Lung Cancer Screening (2), Malignant Solid Neoplasm (2), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Paducah?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Paducah on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Paducah?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Paducah?
Recruiting research sites in Paducah include Mercy Health - Paducah Cancer Center, Baptist Health Paducah, Mercy Health - Paducah Medical Oncology and Hematology, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Paducah right now?
The largest active categories in Paducah are Cancer & tumors (16), Cardiovascular (4). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.