GI oncology Clinical Trials in Portland, OR
As of September 2026, 35 paid clinical trials are recruiting for GI oncology in Portland, Oregon. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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35 clinical trials for GI oncology
·Clear filters·Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy
A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer
A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
FOG-001 in Locally Advanced or Metastatic Solid Tumors
A Study of Sigvotatug Vedotin in Advanced Solid Tumors
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
Efficacy and Safety of Zanidatamab With Standard-of-care Therapy Against Standard-of-care Therapy for Advanced HER2-positive Biliary Tract Cancer
Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors
Study of TDXd, Chemotherapy, Pembrolizumab, and Trastuzumab in First-Line Metastatic HER2-Positive Gastric or Gastroesophageal Junction Cancer
A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease
A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors
A Study of PHN-012 in Patients With Advanced Solid Tumors
cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
A Study to Access Intravenous (IV) Telisotuzumab Adizutecan in Combination With IV Bevacizumab Compared to Standard of Care IV Bevacizumabin Combination With Oral Trifluridine and Tipiracil in Adult Participants With Refractory Metastatic Colorectal Cancer
GPC3-Targeted T-Cell Therapy (ECT204) in Adults With Advanced HCC
A Study of MGC026 in Participants With Advanced Solid Tumors
Study of Orally Administered MOMA-341 in Participants With Advanced or Metastatic Solid Tumors
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
Colonoscopy vs Stool Testing for Older Adults With Colon Polyps
Testing the Addition of Paclitaxel Administered Into the Abdominal Cavity Combined With Chemotherapy for Patients With Gastric Cancer Spread to the Abdominal Cavity
Pancreatic Cancer Early Detection Consortium
A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (FRUITFUL)
Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer
Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics
A Phase II Trial to Evaluate the Effect of Itraconazole on Pathologic Complete Response Rates in Resectable Esophageal Cancer
Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2
A Study of Rilvegostomig or Durvalumab Plus Chemotherapy for First-Line Treatment of Biliary Tract Cancer (ARTEMIDE-Biliary02)
A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation
Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors
A Study of Novel Study Interventions and Combinations in Participants With Colorectal Cancer
Top Research Study Locations in Portland
Researchers run research studies in Portland, OR at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Oregon Health and Science University | Acute Myeloid Leukemia, ARDS, ARDS (Acute Respiratory Distress Syndrome) | 194 |
| Oregon Health & Science University | Heart Failure, Prostate Cancer, Alzheimer Disease | 169 |
| Providence Portland Medical Center | Acute Myeloid Leukemia, Breast Cancer, Malignant Solid Neoplasm | 109 |
| Providence Saint Vincent Medical Center | Acute Myeloid Leukemia, Stage IV Lung Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 86 |
| OHSU Knight Cancer Institute | Acute Myeloid Leukemia, Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm | 45 |
| Providence St. Vincent Medical Center | Carcinoma, Non-Small-Cell Lung, Cardiovascular Diseases, Coronary Artery Disease | 27 |
| VA Portland Health Care System, Portland, OR | Chronic Pain, Tinnitus, Alcohol Use Disorder | 26 |
| Oregon Health Sciences University | Cystic Fibrosis, Prostate Cancer, AAA | 19 |
| Oregon Health & Science University (OHSU) | Advanced Malignant Neoplasm, Advanced Solid Tumor, Aortic Insufficiency | 19 |
| Legacy Emanuel Children's Hospital | Acute Myeloid Leukemia, Ganglioneuroblastoma, Nodular, Malignant Solid Neoplasm | 18 |
| Kaiser Permanente Northwest | Lung Non-Small Cell Carcinoma, Breast Cancer, Recurrent Lung Non-Small Cell Carcinoma | 16 |
| Oregon Health and Sciences University | Acute Cannabis-induced CNS Depression, Acute Respiratory Failure, Anesthesia | 15 |
| Legacy Good Samaritan Hospital and Medical Center | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | 14 |
| Providence Cancer Institute | Advanced Solid Tumor, Fallopian Tube Cancer, Non Small Cell Lung Cancer | 13 |
| OHSU | Acute Kidney Injury, Acute Monocytic Leukemia, Acute Myeloid Leukemia | 11 |
| Providence Cancer Institute Franz Clinic | Breast Cancer, Advanced Breast Cancer, Advanced or Metastatic Solid Tumors | 10 |
| Northwest Cancer Specialists, P.C. | Advanced Non-Small Cell Lung Cancer, Advanced Renal Cell Carcinoma, Advanced or Metastatic Renal Cell Carcinoma | 8 |
| Oregon Health & Sciences University | Cardiac Arrest, Complex Cardiovascular Surgery With Cardiopulmonary Bypass, Cystic Fibrosis | 7 |
| Portland VA Medical Center | Abdominal Aortic Aneurysm, Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum | 7 |
| The Oregon Clinic | Colitis, Ulcerative, Crohn Disease, Chronic Thromboembolic Pulmonary Hypertension | 7 |
| Kaiser Permanente Interstate Medical Office Central | Neoplasm Metastasis, Carcinoma, Non-Small-Cell Lung, Carcinoma, Transitional Cell | 6 |
| Oregon Health & Science University Hospital | Atrial Fibrillation, Basal Ganglia Intracerebral Hemorrhage, Coronary Artery Disease | 6 |
| EyeHealth Northwest | Age-Related Macular Degeneration, Age-related Macular Degeneration (AMD), Choroidal Neovascularization | 5 |
| Kaiser Permanente Center for Health Research | Clostridoides Difficile Associated Disease, Depression, Anxiety, School Health Services | 5 |
| Oregon Dermatology and Research Center | Actinic Keratosis, Moderate to Severe Glabellar Lines, Overweight or Obesity | 5 |
Active & Upcoming Studies in Portland (2026)
Recruiting trials in Portland grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (348 active studies)
- Maximizing Quality of Life After Cancer Through Rehabilitation · VA Office of Research and Development
- Symptom Trajectory Approaches to Research · University of Wisconsin, Madison
Neurology & pain (65 active studies)
- High-Intensity Focused Ultrasonic Ablation of the Centromedian Thalamic Nucleus for Treatment of Medically Refractory Generalized Epilepsy in Patients Ages 18 Years to 89 Years · Oregon Health and Science University
- COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE" · Phase 3 · Yale University
Cardiovascular (48 active studies)
- Precision T1D Platform - New Therapies for Cardio-Renal Complications · Phase 2 · Oregon Health and Science University
- A Prospective, Randomized Multicenter Clinical Trial of the TricValve® Transcatheter Bicaval Valve System in Subjects With Severe Tricuspid Regurgitation. · P+F Products + Features USA Inc.
Diabetes & metabolic (23 active studies)
- Precision T1D Platform - New Therapies for Cardio-Renal Complications · Phase 2 · Oregon Health and Science University
- A Study to Evaluate Effect of AZD6234 as an Adjunct to Incretin-based Therapies in Adult Participants With Obesity or Overweight With Weight-related Comorbidity With or Without Type 2 Diabetes Mellitus · Phase 3 · AstraZeneca
Mental health & behavior (18 active studies)
- Psilocybin Intervention for Veterans Overcoming Treatment-Resistant Depression · Phase 3 · VA Office of Research and Development
- Digitally Enhanced Peer Doula Model for Perinatal Patients With Substance Use Disorder · Trustees of Dartmouth College
Eye & vision (15 active studies)
- A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated · Phase 1, Phase 2 · Boehringer Ingelheim
- A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002) · Phase 2, Phase 3 · EyeBiotech Ltd.
Pediatric (8 active studies)
- Implementing Powered Mobility in Early Childhood Settings for Children With Cerebral Palsy · Oregon Health and Science University
- A Study of Nipocalimab or Intravenous Immunoglobulin (IVIG) in Pregnancies At Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT) · Phase 3 · Janssen Research & Development, LLC
Vaccines (5 active studies)
- A Study on the Efficacy of a Vaccine Against Influenza in Adults ≥65 Years of Age · Phase 3 · GlaxoSmithKline
- Immune-mediated Pathogenic Mechanisms of Neuro-PASC in Veterans · VA Office of Research and Development
Common conditions studied in Portland
- Acute Myeloid Leukemia (18 active studies)
- Endometrial Cancer (17 active studies)
- Breast Cancer (16 active studies)
- Heart Failure (14 active studies)
- Ovarian Cancer (13 active studies)
- Prostate Cancer (13 active studies)
Leading research sponsors in Portland
- Oregon Health and Science University
- OHSU Knight Cancer Institute
- National Cancer Institute (NCI)
- AstraZeneca
- VA Office of Research and Development
Frequently asked questions
How many paid clinical trials are currently recruiting in Portland?
There are approximately 1,003 recruiting clinical trials in Portland, Oregon listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Portland pay participants?
Most recruiting trials in Portland compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Portland?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Portland?
The most common conditions under active study in Portland include Acute Myeloid Leukemia (18), Endometrial Cancer (17), Breast Cancer (16), Heart Failure (14), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Portland?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Portland on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Portland?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Portland?
Recruiting research sites in Portland include Oregon Health and Science University, Oregon Health & Science University, Providence Portland Medical Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Portland right now?
The largest active categories in Portland are Cancer & tumors (348), Neurology & pain (65), Cardiovascular (48). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.