MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
for Lumbar Spinal Stenosis
Sites in Saint Cloud, Sartell +2341 more locations
Sponsor: Stryker Instruments
Sex: All·Age: 18+
Code: NCT03072927·Recruiting·Listed Mar 2017
Paid Clinical Trials in Saint Cloud, MN
As of July 2026, 57 paid clinical trials are recruiting in Saint Cloud, Minnesota. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Saint Cloud offers studies at sites including Coborn Cancer Center at Saint Cloud Hospital for conditions such as Stage IVB Prostate Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Coronary Artery Disease, Heart Failure. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Saint Cloud
Trials by drug in Saint Cloud
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56 clinical trials
Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
for High Risk Cardiovascular Disease
Drug: Zilebesiran
Sites in Saint Cloud, Richfield +259 more locations
Sponsor: Alnylam Pharmaceuticals
Sex: All·Age: 18+
Code: NCT07181109·Phase 3·Recruiting·Listed Sep 2025
Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure
for Heart Failure - NYHA II - IV
Sites in Saint Cloud, Duluth +33 more locations
Sponsor: Boston Scientific Corporation
Sex: All·Age: 18+
Code: NCT07069738·Recruiting·Listed Jul 2025
REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE
for Aortic Stenosis
Sites in Saint Cloud, Minneapolis +69 more locations
Sponsor: Medtronic Cardiovascular
Sex: All·Age: 18 - 105
Code: NCT06777368·Recruiting·Listed Jan 2025
PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III
for Heart Failure NYHA Class II
Sites in Saint Cloud, Minneapolis +43 more locations
Sponsor: Endotronix, Inc.
Sex: All·Age: 18+
Code: NCT05934487·Recruiting·Listed Jul 2023
Prevail Global Study
for Coronary Artery Disease
Sites in Saint Cloud, Edina +49 more locations
Sponsor: Medtronic Vascular
Sex: All·Age: 18+
Code: NCT06535854·Recruiting·Listed Aug 2024
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
for Functional Mitral Regurgitation
Sites in Saint Cloud +50 more locations
Sponsor: Cardiac Dimensions, Inc.
Sex: All·Age: 18+
Code: NCT03142152·Recruiting·Listed May 2017
J-Valve Transfemoral Pivotal Study
for Aortic Valve Regurgitation
Sites in Saint Cloud, Minneapolis +32 more locations
Sponsor: JC Medical, Inc., an affiliate of Edwards Lifesciences LLC
Sex: All·Age: 18+
Code: NCT06455787·Recruiting·Listed Jun 2024
PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR
for Aortic Stenosis, Calcific
Sites in Saint Cloud, Minneapolis +48 more locations
Sponsor: Edwards Lifesciences
Sex: All·Age: 65+
Code: NCT04889872·Recruiting·Listed May 2021
Pivotal Study of the SUpira System in Patients Undergoing High-Risk Percutaneous COronaRy InTervention (HRPCI)
for Coronary Artery Disease
Sites in Saint Cloud +18 more locations
Sponsor: Supira Medical
Sex: All·Age: 18 - 90
Code: NCT07296744·Recruiting·Listed Dec 2025
EFS of the CardioMech MVRS
for Mitral Regurgitation
Sites in Saint Cloud, Rochester +8 more locations
Sponsor: CardioMech AS
Sex: All·Age: 18+
Code: NCT04820764·Recruiting·Listed Mar 2021
Safety and Effectiveness of the Akura Thrombectomy System for Use in the Removal of Emboli From the Pulmonary Arteries in Treating Acute Pulmonary Embolism (PE)
for Pulmonary Embolism Acute
Sites in Saint Cloud +9 more locations
Sponsor: Akura Medical
Sex: All·Age: 18+
Code: NCT06672510·Recruiting·Listed Nov 2024
xDot Access Management System Early Feasibility Study
for Vascular Closure Devices
Sites in Saint Cloud +2 more locations
Sponsor: xDot Medical, Inc
Sex: All·Age: 18 - 80
Code: NCT07464353·Recruiting·Listed Mar 2026
Acute Pulmonary Embolism Treatment With the AlphaVac Multipurpose Mechanical Aspiration System and the AlphaReturn Blood Management System: Evaluation of Safety and Effectiveness
for Pulmonary Embolism Acute
Sites in Saint Cloud +5 more locations
Sponsor: Angiodynamics, Inc.
Sex: All·Age: 18+
Code: NCT07280247·Recruiting·Listed Dec 2025
Comparing the Safety and Efficacy of ASI-02 to Agitated Saline for Suspected Right-to-left Shunt
for Right-To-Left Shunt
Sites in Saint Cloud, Rochester +5 more locations
Sponsor: Agitated Solutions, Inc.
Sex: All·Age: 18+
Code: NCT06938347·Phase 3·Recruiting·Listed Apr 2025
ProACT Post-Approval Study
for Stress Urinary Incontinence
Sites in Saint Cloud +5 more locations
Sponsor: Uromedica
Sex: Male·Age: 50+·Accepts healthy volunteers
Code: NCT03767595·Recruiting·Listed Dec 2018
Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA RLT and Its Effect on Patients With Advanced Prostate Cancer, RECIPROCAL Trial
for Metastatic Castration-Resistant Prostate Carcinoma
Sites in Saint Cloud +61 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: Male·Age: 18+
Code: NCT07200830·Phase 3·Recruiting·Listed Oct 2025
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
for Lung Non-Small Cell Carcinoma
Sites in Saint Cloud, Coon Rapids +633 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT04267848·Phase 3·Recruiting·Listed Feb 2020
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
for Breast Cancer
Sites in Saint Cloud, Monticello +1103 more locations
Sponsor: NRG Oncology
Sex: Female·Age: 18 - 60
Code: NCT05879926·Phase 3·Recruiting·Listed May 2023
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
for Stage III Colon Cancer
Sites in Saint Cloud, Monticello +920 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT05174169·Phase 2, Phase 3·Recruiting·Listed Dec 2021
Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study
for Chronic Lymphocytic Leukemia
Sites in Saint Cloud, Coon Rapids +296 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT04269902·Phase 3·Recruiting·Listed Feb 2020
Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab
for Anatomic Stage II Breast Cancer AJCC v8
Sites in Saint Cloud, Coon Rapids +774 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT05812807·Phase 3·Recruiting·Listed Apr 2023
Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery
for Head and Neck Squamous Cell Carcinoma
Sites in Saint Cloud, Monticello +464 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 18+
Code: NCT02734537·Phase 2·Recruiting·Listed Apr 2016
ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab
for Anatomic Stage I Breast Cancer AJCC v8
Sites in Saint Cloud, Coon Rapids +583 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT06876714·Phase 3·Recruiting·Listed Mar 2025
mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma
for Advanced Esophageal Adenocarcinoma
Drug: Nivolumab
Sites in Saint Cloud, Monticello +641 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT05677490·Phase 3·Recruiting·Listed Jan 2023
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
for Acute Lymphoblastic Leukemia
Sites in Saint Cloud, Monticello +629 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 40 - 75·Accepts healthy volunteers
Code: NCT05334069·Recruiting·Listed Apr 2022
Collection of Research Data and Samples From Patients Who Experience Immunotherapy Side Effects
for Malignancy
Sites in Saint Cloud, Monticello +403 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: All ages
Code: NCT04242095·Recruiting·Listed Jan 2020
Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial
for Extensive Stage Lung Small Cell Carcinoma
Drug: Atezolizumab
Sites in Saint Cloud, Coon Rapids +271 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT04402788·Phase 2, Phase 3·Recruiting·Listed May 2020
Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study
for Muscle Invasive Bladder Urothelial Carcinoma
Sites in Saint Cloud, Coon Rapids +445 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT05987241·Phase 2, Phase 3·Recruiting·Listed Aug 2023
Testing Continuous Versus Intermittent Treatment With the Study Drug Zanubrutinib for Older Patients With Previously Untreated Mantle Cell Lymphoma
for Mantle Cell Lymphoma
Sites in Saint Cloud, Coon Rapids +225 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 60+
Code: NCT05976763·Phase 3·Recruiting·Listed Aug 2023
Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response
for Prostate Cancer (Adenocarcinoma)
Sites in Saint Cloud, Baxter +357 more locations
Sponsor: Canadian Cancer Trials Group
Sex: Male·Age: 18+
Code: NCT06592924·Phase 3·Recruiting·Listed Sep 2024
Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer
for Clear Cell Renal Cell Carcinoma
Sites in Saint Cloud, Coon Rapids +403 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT06661720·Phase 3·Recruiting·Listed Oct 2024
Comparing Impact of Treatment Before or After Surgery in Patients With Stage II-IIIB Resectable Non-small Cell Lung Cancer
for Resectable Lung Non-Small Cell Carcinoma
Sites in Saint Cloud, Monticello +306 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT06632327·Phase 3·Recruiting·Listed Oct 2024
Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer
for Locally Advanced Lung Non-Small Cell Carcinoma
Sites in Saint Cloud, Brainerd +444 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT05624996·Phase 3·Recruiting·Listed Nov 2022
Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging
for Biochemically Recurrent Prostate Carcinoma
Drug: Apalutamide
Sites in Saint Cloud, Monticello +276 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: Male·Age: 18+
Code: NCT04423211·Phase 3·Recruiting·Listed Jun 2020
Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial
for Castration-Sensitive Prostate Carcinoma
Drug: Apalutamide
Sites in Saint Cloud, Bemidji +188 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: Male·Age: 18+
Code: NCT06931340·Phase 3·Recruiting·Listed Apr 2025
Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain
for Anatomic Stage IV Breast Cancer AJCC v8
Sites in Saint Cloud, Monticello +255 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT06500455·Phase 3·Recruiting·Listed Jul 2024
Radiotherapy to Block Oligoprogression In Metastatic Non-Small-Cell Lung Cancer
for Non-small Cell Lung Cancer
Sites in Saint Cloud, Duluth +69 more locations
Sponsor: Canadian Cancer Trials Group
Sex: All·Age: 18+
Code: NCT06686771·Phase 3·Recruiting·Listed Nov 2024
Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients Receiving the Usual Chemotherapy Treatment for Bladder Cancer, ARCHER Study
for Muscle Invasive Bladder Urothelial Carcinoma
Sites in Saint Cloud, Monticello +206 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT07097142·Phase 3·Recruiting·Listed Jul 2025
Testing the Combination of Two Approved Drugs and One Experimental Drug in Patients With Relapsed or Refractory Multiple Myeloma
for Recurrent Multiple Myeloma
Sites in Saint Cloud +39 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT06232044·Phase 1, Phase 2·Recruiting·Listed Jan 2024
Top Research Study Locations in Saint Cloud
Researchers run research studies in Saint Cloud, MN at 16 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Coborn Cancer Center at Saint Cloud Hospital | Stage IVB Prostate Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8 | 30 |
| CentraCare Heart and Vascular Center | Aortic Stenosis, Aortic Stenosis, Calcific, Aortic Valve Disease Mixed | 7 |
| CentraCare | Coronary Artery Disease, High Risk Percutaneous Coronary Intervention, Interventional Cardiology | 2 |
| St Cloud Hospital | ARDS, Fluid Responsiveness, Mechanical Power | 2 |
| St. Cloud Hospital | Atrial Fibrillation, Colon Adenoma, Colon Lesion | 2 |
| Centra Care Heart Center | Heart Failure, Heart Failure NYHA Class II, Heart Failure NYHA Class III | 1 |
| CentraCare - St. Cloud Hospital | Hypertension, Intracerebral Hemorrhage, Stroke | 1 |
| CentraCare Heart & Vascular Center | Mitral Regurgitation | 1 |
| CentraCare Heart & Vascular Center MN - Saint Cloud Hospital | Coronary Artery Disease | 1 |
| CentraCare Heart and Vascular | Cardiovascular Diseases, Functional Mitral Regurgitation, Heart Diseases | 1 |
| CentraCare Plaza | Lumbar Spinal Stenosis | 1 |
| CentraCare- St. Cloud | Stress Urinary Incontinence | 1 |
| Centracare Heart & Vascular Center | Pulmonary Embolism Acute | 1 |
| Clinical Trial Site | High Cardiovascular Risk, High Risk Cardiovascular Disease, Hypertension | 1 |
| St Cloud Hosp | Lumbar Spinal Stenosis | 1 |
| St. Cloud (CentraCare) | High-Risk Percutaneous Coronary Intervention | 1 |
Active & Upcoming Studies in Saint Cloud (2026)
Recruiting trials in Saint Cloud grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (29 active studies)
- Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA RLT and Its Effect on Patients With Advanced Prostate Cancer, RECIPROCAL Trial · Phase 3 · Alliance for Clinical Trials in Oncology
- Radiotherapy to Block Oligoprogression In Metastatic Non-Small-Cell Lung Cancer · Phase 3 · Canadian Cancer Trials Group
Cardiovascular (12 active studies)
Neurology & pain (1 active study)
- Clevidipine for the Antihypertensive Treatment of Acute Intracerebral Hemorrhage · Zeenat Qureshi Stroke Institute
Common conditions studied in Saint Cloud
- Stage IVB Prostate Cancer AJCC v8 (4 active studies)
- Anatomic Stage II Breast Cancer AJCC v8 (3 active studies)
- Coronary Artery Disease (3 active studies)
- Heart Failure (3 active studies)
- Anatomic Stage I Breast Cancer AJCC v8 (2 active studies)
- Anatomic Stage IIIA Breast Cancer AJCC v8 (2 active studies)
Leading research sponsors in Saint Cloud
- Alliance for Clinical Trials in Oncology
- NRG Oncology
- National Cancer Institute (NCI)
- AstraZeneca
- Canadian Cancer Trials Group
Frequently asked questions
How many paid clinical trials are currently recruiting in Saint Cloud?
There are approximately 57 recruiting clinical trials in Saint Cloud, Minnesota listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Saint Cloud pay participants?
Most recruiting trials in Saint Cloud compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Saint Cloud?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Saint Cloud?
The most common conditions under active study in Saint Cloud include Stage IVB Prostate Cancer AJCC v8 (4), Anatomic Stage II Breast Cancer AJCC v8 (3), Coronary Artery Disease (3), Heart Failure (3), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Saint Cloud?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Saint Cloud on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Saint Cloud?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Saint Cloud?
Recruiting research sites in Saint Cloud include Coborn Cancer Center at Saint Cloud Hospital, CentraCare Heart and Vascular Center, CentraCare, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Saint Cloud right now?
The largest active categories in Saint Cloud are Cancer & tumors (29), Cardiovascular (12), Neurology & pain (1). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
Browse more clinical trials
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