Paid Clinical Trials in Saint Paul, MN
As of July 2026, 173 paid clinical trials are recruiting in Saint Paul, Minnesota. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Saint Paul offers studies at sites including Regions Hospital for conditions such as Acute Myeloid Leukemia, Stage IV Lung Cancer AJCC v8, Non-Small Cell Lung Cancer, Stage IIIB Lung Cancer AJCC v8. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Saint Paul
Trials by drug in Saint Paul
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Newly added in Saint Paul
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
162 clinical trials
A Trial to Investigate Safety, Exposure, and Efficacy of HU6 Compared With Placebo in Adult Participants With Metabolic Dysfunction-associated Steatohepatitis (MASH)
A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer
A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)
A Study of Pasritamig With Docetaxel Versus Docetaxel in Participants With Metastatic Castration-Resistant Prostate Cancer
Symbiotic-GI-13: A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body.
A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)
A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer
A Study of Sigvotatug Vedotin in Advanced Solid Tumors
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.
A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)
Study of STK-012 Alone and With Other Treatments in Patients With Advanced Lung Cancer and Other Cancers
A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors
A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease
A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease
A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)
Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients
Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1
SuperSaturated Oxygen Comprehensive Observational Registry
TTX-080 HLA-G Antagonist in Subjects With Advanced Cancers
A Clinical Efficacy and Safety Study of OHB-607 in Preventing Bronchopulmonary Dysplasia in Extremely Premature Infants
A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors
Prevalence of Antibodies and Cytokines in Participants With Chronic Granulomatous Disease
A Solid Tumor Study for Long Term Treatment of Cancer Patients Who Participated in Adagrasib Studies
A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer
A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)
A Study of ASP1002 in Adults for Treatment of Solid Tumors
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
The FLOTILLA Study: Providing Continued Access to The Study Medicines Encorafenib and Binimetinib for Participants in Prior Clinical Trials
A Study of HC-7366 in Combination With Belzutifan (WELIREG™) in Patients With Renal Cell Carcinoma
Respiration Measured Via End-tidal CO2 and Spirometry Study (RESPI)
Evaluate the Effect of Vimseltinib on Pharmacokinetics of Combined Oral Contraceptive (Ethinyl Estradiol/Levonorgestrel)
How's Your Balance?
Safety, Tolerability, and Pharmacokinetics of ASCT-83 in Healthy Adults
Establishing the Preliminary Utility of a Novel Pediatric Manual Mobile Standing Wheelchair
A Study to Learn How the Body Processes the Study Medicine PF-07328948 in People With Reduced Kidney Function
Proof of Concept Study of Vaginal AZU-101 in Vulvovaginal Atrophy in Postmenopausal Women
ATTUNE: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intrathecally-Administered ION440 in Participants With Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome (MDS)
Top Research Study Locations in Saint Paul
Researchers run research studies in Saint Paul, MN at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Regions Hospital | Acute Myeloid Leukemia, Stage IV Lung Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8 | 98 |
| United Hospital | Acute Myeloid Leukemia, Stage IV Lung Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 80 |
| Gillette Children's Specialty Healthcare | Cerebral Palsy, Chronic Post Surgical Pain, Fracture Distal Radius | 8 |
| HealthPartners Neuroscience Center | Alzheimer Disease, Alzheimer's Disease, Anxiety | 8 |
| HealthPartners Cancer Center at Regions Hospital | 1st Line NSCLC, Advanced Solid Tumor, Breast Cancer | 5 |
| Children's Minnesota | Hypothalamic Obesity, Prader-Willi Syndrome, Childhood-onset Combined Pituitary Hormone Deficiency | 4 |
| HealthPartners Cancer Research Center | Advanced Solid Tumors, Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis | 4 |
| Allina Health Cancer Institute - United Hospital | Advanced Hepatocellular Carcinoma, Carcinoma, Hepatocellular, Carcinoma, Non-Small Cell Lung | 3 |
| Nucleus Network | Healthy, Healthy Participants, Renal Impairment | 3 |
| Ascendis Investigational Site | Achondroplasia | 2 |
| Regions Hospital Pharmacy | Advanced or Metastatic Solid Tumors, Brain Neoplasms, Differentiated Thyroid Cancer | 2 |
| Ain Dah Yung Center | Mental Health Wellness 1, Parenting, Risky Health Behavior | 1 |
| Allina Health Cancer Institute | Carcinoma, Non-Small Cell Lung, Cutaneous Squamous Cell Cancer, Esophageal Adenocarcinoma | 1 |
| Allina Health Cancer Institute-United(VPCI) | Colorectal Neoplasms | 1 |
| Ascendis Pharma Investigational Site | Idiopathic Short Stature, Short Stature Homeobox Gene Mutation, Small for Gestational Age at Delivery | 1 |
| Boston Scientific Arden Hills | Respiration Rate Detection | 1 |
| Children's Minnesota - Children's Hospital and Clinics | Bronchopulmonary Dysplasia, Chronic Lung Disease of Prematurity, Intraventricular Hemorrhage | 1 |
| Children's Minnesota - Children's Hospital and Clinics - St. Paul | Bronchopulmonary Dysplasia, Chronic Lung Disease of Prematurity, Intraventricular Hemorrhage | 1 |
| Children's Minnesota Pediatric Endocrinology Clinic & McNeeley Diabetes Center | Obesity, Overweight | 1 |
| Clinical Study Site | Non-Small Cell Lung Cancer | 1 |
| Driven to Discover Research Facility at the Minnesota State Fair | Balance Assessment, Falls, Plantar Sensation | 1 |
| Gillette Children's | Cerebral Palsy | 1 |
| Health Partners - Regions Hospital | Ductal Carcinoma in Situ | 1 |
| Health Partners Cancer Center at Regions Hospital | Advanced Solid Tumor, Bladder Cancer, Breast Cancer | 1 |
| HealthEast Care System | Bone Fracture | 1 |
Active & Upcoming Studies in Saint Paul (2026)
Recruiting trials in Saint Paul grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (103 active studies)
- Study of Izalontamab Brengitecan (BMS-986507) in Combination With Osimertinib Versus Osimertinib Monotherapy or Osimertinib in Combination With Platinum-based Chemotherapy for EGFRmt Non-small Cell Lung Cancer (IZABRIGHT-Lung02) · Phase 3 · Bristol-Myers Squibb
- Testing the Addition of Anti-Cancer Drug Sonrotoclax, to the Standard Treatment Zanubrutinib, for Previously Untreated CLL/SLL · Phase 3 · Alliance for Clinical Trials in Oncology
Neurology & pain (5 active studies)
- Safety, Tolerability, and Pharmacokinetics of ASCT-83 in Healthy Adults · Phase 1 · Alcamena Stem Cell Therapeutics
- A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3) · Phase 3 · Bristol-Myers Squibb
Mental health & behavior (4 active studies)
- The Effect of the Safe and Sound Protocol on Depression and Anxiety Symptoms · HealthPartners Institute
- TMS in Anxiety-Parkinson's Disease · HealthPartners Institute
Diabetes & metabolic (4 active studies)
- A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus and Impaired Renal Function on Background Dapagliflozin · Phase 3 · AstraZeneca
- A Trial of Setmelanotide in Patients With Congenital Hypothalamic Obesity (Sub-study of NCT05774756) · Phase 3 · Rhythm Pharmaceuticals, Inc.
Cardiovascular (2 active studies)
- A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart · Phase 3 · Boehringer Ingelheim
- Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function · Phase 3 · AstraZeneca
Common conditions studied in Saint Paul
- Acute Myeloid Leukemia (6 active studies)
- Stage IV Lung Cancer AJCC v8 (6 active studies)
- Non-Small Cell Lung Cancer (5 active studies)
- Stage IIIB Lung Cancer AJCC v8 (5 active studies)
- Anatomic Stage II Breast Cancer AJCC v8 (4 active studies)
- Breast Cancer (4 active studies)
Leading research sponsors in Saint Paul
- National Cancer Institute (NCI)
- SWOG Cancer Research Network
- Alliance for Clinical Trials in Oncology
- NRG Oncology
- HealthPartners Institute
Frequently asked questions
How many paid clinical trials are currently recruiting in Saint Paul?
There are approximately 173 recruiting clinical trials in Saint Paul, Minnesota listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Saint Paul pay participants?
Most recruiting trials in Saint Paul compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Saint Paul?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Saint Paul?
The most common conditions under active study in Saint Paul include Acute Myeloid Leukemia (6), Stage IV Lung Cancer AJCC v8 (6), Non-Small Cell Lung Cancer (5), Stage IIIB Lung Cancer AJCC v8 (5), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Saint Paul?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Saint Paul on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Saint Paul?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Saint Paul?
Recruiting research sites in Saint Paul include Regions Hospital, United Hospital, Gillette Children's Specialty Healthcare, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Saint Paul right now?
The largest active categories in Saint Paul are Cancer & tumors (103), Neurology & pain (5), Mental health & behavior (4). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.