Oncology Clinical Trials in Saint Paul, MN
As of August 2026, 53 paid clinical trials are recruiting for Oncology in Saint Paul, Minnesota. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Saint Paul
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
54 clinical trials for Oncology
·Clear filters·A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer
A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)
Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Symbiotic-GI-13: A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body.
A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer
A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.
A Study of Sigvotatug Vedotin in Advanced Solid Tumors
A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors
A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)
Study of STK-012 Alone and With Other Treatments in Patients With Advanced Lung Cancer and Other Cancers
Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1
TTX-080 HLA-G Antagonist in Subjects With Advanced Cancers
A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors
A Solid Tumor Study for Long Term Treatment of Cancer Patients Who Participated in Adagrasib Studies
A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer
A Study of ASP1002 in Adults for Treatment of Solid Tumors
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
The FLOTILLA Study: Providing Continued Access to The Study Medicines Encorafenib and Binimetinib for Participants in Prior Clinical Trials
A Study of HC-7366 in Combination With Belzutifan (WELIREG™) in Patients With Renal Cell Carcinoma
Study of Tarlatamab + ZL-1310 +/- Anti-programmed Death Ligand 1 (Anti-PD-L1) in Small Cell Lung Cancer (SCLC)
Study of RAS(ON) Inhibitors in Combination With Ivonescimab in Patients With Solid Tumors
Testing the Addition of Anti-Cancer Drug Sonrotoclax, to the Standard Treatment Zanubrutinib, for Previously Untreated CLL/SLL
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
Cost Communication and Financial Navigation in Cancer Patients (COSTCOM)
Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging
Axelopran for Advanced Cancer in Patients Receiving Opioids
A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer
MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)
Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial
BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study
Testing Continuous Versus Intermittent Treatment With the Study Drug Zanubrutinib for Older Patients With Previously Untreated Mantle Cell Lymphoma
Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial
Testing New Therapies for Patients With Acute Myeloid Leukemia Who Are Newly Diagnosed and Have Not Yet Started Treatment (A MyeloMATCH Treatment Trial)
Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)
Top Research Study Locations in Saint Paul
Researchers run research studies in Saint Paul, MN at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Regions Hospital | Acute Myeloid Leukemia, Stage IV Lung Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 97 |
| United Hospital | Acute Myeloid Leukemia, Stage IV Lung Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 79 |
| Gillette Children's Specialty Healthcare | Cerebral Palsy, Chronic Post Surgical Pain, Fracture Distal Radius | 8 |
| HealthPartners Neuroscience Center | Alzheimer Disease, Alzheimer's Disease, Anxiety | 8 |
| HealthPartners Cancer Center at Regions Hospital | 1st Line NSCLC, Advanced Solid Tumor, Breast Cancer | 5 |
| Allina Health Cancer Institute - United Hospital | Advanced Hepatocellular Carcinoma, Advanced Non-Small Cell Lung Cancer, Carcinoma, Hepatocellular | 4 |
| HealthPartners Cancer Research Center | Advanced Solid Tumors, Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis | 4 |
| Children's Minnesota | Hypothalamic Obesity, Childhood-onset Combined Pituitary Hormone Deficiency, Multiple Pituitary Hormone Deficiency Genetic Form | 3 |
| Health Partners Cancer Center at Regions Hospital | Non-small Cell Lung Cancer (NSCLC), Advanced Solid Tumor, Advanced Solid Tumors | 3 |
| Nucleus Network | Healthy, Healthy Participants, Renal Impairment | 3 |
| Ascendis Investigational Site | Achondroplasia | 2 |
| Regions Hospital Pharmacy | Advanced or Metastatic Solid Tumors, Brain Neoplasms, Differentiated Thyroid Cancer | 2 |
| Ain Dah Yung Center | Mental Health Wellness 1, Parenting, Risky Health Behavior | 1 |
| Allina Health Cancer Institute | Carcinoma, Non-Small Cell Lung, Cutaneous Squamous Cell Cancer, Esophageal Adenocarcinoma | 1 |
| Allina Health Cancer Institute-United(VPCI) | Colorectal Neoplasms | 1 |
| Ascendis Pharma Investigational Site | Idiopathic Short Stature, Short Stature Homeobox Gene Mutation, Small for Gestational Age at Delivery | 1 |
| Boston Scientific Arden Hills | Respiration Rate Detection | 1 |
| Children's Minnesota Pediatric Endocrinology Clinic & McNeeley Diabetes Center | Obesity, Overweight | 1 |
| Clinical Study Site | Non-Small Cell Lung Cancer | 1 |
| Driven to Discover Research Facility at the Minnesota State Fair | Balance Assessment, Falls, Plantar Sensation | 1 |
| Gillette Children's | Cerebral Palsy | 1 |
| Health Partners - Regions Hospital | Ductal Carcinoma in Situ | 1 |
| HealthEast Care System | Bone Fracture | 1 |
| HealthPartners | Oral Leukoplakia | 1 |
| HealthPartners Cancer Center at Regions Hospital CRC East | Prostatic Neoplasms, Castration-Resistant | 1 |
Active & Upcoming Studies in Saint Paul (2026)
Recruiting trials in Saint Paul grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (105 active studies)
- Study of Izalontamab Brengitecan (BMS-986507) in Combination With Osimertinib Versus Osimertinib Monotherapy or Osimertinib in Combination With Platinum-based Chemotherapy for EGFRmt Non-small Cell Lung Cancer (IZABRIGHT-Lung02) · Phase 3 · Bristol-Myers Squibb
- Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial · Phase 3 · National Cancer Institute (NCI)
Neurology & pain (5 active studies)
- Safety, Tolerability, and Pharmacokinetics of ASCT-83 in Healthy Adults · Phase 1 · Alcamena Stem Cell Therapeutics
- A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3) · Phase 3 · Bristol-Myers Squibb
Mental health & behavior (4 active studies)
- The Effect of the Safe and Sound Protocol on Depression and Anxiety Symptoms · HealthPartners Institute
- TMS in Anxiety-Parkinson's Disease · HealthPartners Institute
Diabetes & metabolic (4 active studies)
- A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus and Impaired Renal Function on Background Dapagliflozin · Phase 3 · AstraZeneca
- A Trial of Setmelanotide in Patients With Congenital Hypothalamic Obesity (Sub-study of NCT05774756) · Phase 3 · Rhythm Pharmaceuticals, Inc.
Cardiovascular (2 active studies)
- A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart · Phase 3 · Boehringer Ingelheim
- Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function · Phase 3 · AstraZeneca
Common conditions studied in Saint Paul
- Acute Myeloid Leukemia (6 active studies)
- Stage IV Lung Cancer AJCC v8 (6 active studies)
- Anatomic Stage II Breast Cancer AJCC v8 (5 active studies)
- Non-Small Cell Lung Cancer (5 active studies)
- Breast Cancer (4 active studies)
- Malignant Solid Neoplasm (4 active studies)
Leading research sponsors in Saint Paul
- National Cancer Institute (NCI)
- SWOG Cancer Research Network
- Alliance for Clinical Trials in Oncology
- NRG Oncology
- HealthPartners Institute
Frequently asked questions
How many paid clinical trials are currently recruiting in Saint Paul?
There are approximately 176 recruiting clinical trials in Saint Paul, Minnesota listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Saint Paul pay participants?
Most recruiting trials in Saint Paul compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Saint Paul?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Saint Paul?
The most common conditions under active study in Saint Paul include Acute Myeloid Leukemia (6), Stage IV Lung Cancer AJCC v8 (6), Anatomic Stage II Breast Cancer AJCC v8 (5), Non-Small Cell Lung Cancer (5), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Saint Paul?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Saint Paul on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Saint Paul?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Saint Paul?
Recruiting research sites in Saint Paul include Regions Hospital, United Hospital, Gillette Children's Specialty Healthcare, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Saint Paul right now?
The largest active categories in Saint Paul are Cancer & tumors (105), Neurology & pain (5), Mental health & behavior (4). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.