Role of Interleukin-6 in Exercise

Sponsor
University of Zurich
Study ID
NCT01073826
Status
Completed

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 75 Years
Healthy Volunteers
Not accepted

Interventions

  • Sport — BEHAVIORAL
  • Tocilizumab — DRUG
  • Sitagliptin — DRUG

Study Details

The purpose of the study is to understand the role of interleukin-6 during physical activity in patients with type 2 diabetes.

Key Dates

Start date
Feb 28, 2010
Status verified
Oct 2016
Primary completion
Nov 30, 2015
Completion
Jun 30, 2016

Study Design

Enrollment
56 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION

Arms

  • Active Comparator: Tocilizumab
    Infusion of Tocilizumab and sport intervention
  • Active Comparator: Sitagliptin
    Intake of Sitagliptin and sport intervention
  • Placebo Comparator: Placebo
    Intake of placebo and sport intervention

Primary Outcome Measure

Glucagon like peptide- 1 (GLP-1) [ Time Frame: Change in GLP-1 secretion compared to baseline ]

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