Study of the Effect of Fostamatinib Twice Daily on Blood Pressure in Patients With Rheumatoid Arthritis

Part of paid clinical trials in Huntsville, Alabama.

Sponsor
AstraZeneca
Study ID
NCT01563978
Phase
PHASE2
Status
Completed

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • fostamatinib — DRUG
    fostamatinib 100 mg twice daily
  • placebo — DRUG
    placebo

Study Details

The purpose of this study is to evaluate the effect of fostamatinib compared to placebo on ambulatory blood pressure in patients with active rheumatoid arthritis who are taking a disease-modifying anti-rheumatic drug (DMARD). The study will last for 57 days.

Key Dates

Start date
Apr 30, 2012
Status verified
Apr 2014
Primary completion
Jan 31, 2013
Completion
Jan 31, 2013

Study Design

Enrollment
266 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Dosing Regimen A
    Oral treatment
  • Placebo Comparator: Dosing Regimen B
    Oral treatment

Primary Outcome Measure

Change From Baseline in 24-hour Mean Ambulatory SBP [ Time Frame: 4 weeks ]

Locations (30)

FacilityCityStateZIPSite coordinators
Research SiteHuntsvilleAlabama--
Research SiteHuntington BeachCalifornia--
Research SiteSanta MariaCalifornia--
Research SiteTrumbullConnecticut--
Research SiteBoca RatonFlorida--
Research SiteBrandonFlorida--
Research SiteOrlandoFlorida--
Research SiteTampaFlorida--
Research SiteVeniceFlorida--
Research SiteDecaturGeorgia--
Research SiteSouth BendIndiana--
Research SiteCumberlandMaryland--
Research SiteFrederickMaryland--
Research SiteHagerstownMaryland--
Research SiteFlorissantMissouri--
Research SiteRichmond HeightsMissouri--
Research SiteFreeholdNew Jersey--
Research SiteAlbuquerqueNew Mexico--
Research SiteBrooklynNew York--
Research SiteCharlotteNorth Carolina--
Research SiteGreensboroNorth Carolina--
Research SiteLake OswegoOregon--
Research SiteDuncansvillePennsylvania--
Research SiteMemphisTennessee--
Research SiteAustinTexas--
Research SiteDallasTexas--
Research SiteHoustonTexas--
Research SiteLubbockTexas--
Research SiteNassau BayTexas--
Research SiteTacomaWashington--

Find similar trials in Huntsville, AL

By condition
Rheumatoid arthritis
By specialty
RheumatologyAutoimmune diseaseMusculoskeletal disorders
By research site
Research Site· Huntsville, ALResearch Site· Huntington Beach, CAResearch Site· Santa Maria, CAResearch Site· Trumbull, CTResearch Site· Boca Raton, FLResearch Site· Brandon, FL

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