Rheumatoid arthritis Clinical Trials

Recruiting rheumatoid arthritis studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat rheumatoid arthritis. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting rheumatoid arthritis studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting rheumatoid arthritis trials

Within

Safety and Tolerability of a Single Intravenous Infusion of BX-U001 in Refractory Rheumatoid Arthritis

for Rheumatoid Arthritis

Sponsor: Baylx Inc.

Sex: All·Age: 18 - 70

Code: NCT03828344·Phase 1

A Trial in Healthy Adult Participants and Adults With Autoimmune Disease to Test How HBM7020 is Tolerated and Absorbed in the Body

for Rheumatoid Arthritis

Sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc.

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT07649265·Phase 1

A Phase 1, First-in-Human Study of CND319 in Healthy Participants and Patients With Rheumatic Diseases

for Healthy Participants Study

Sponsor: Candid Therapeutics

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07712939·Phase 1

Apply to this trial

Natrunix in Combination With Methotrexate for Rheumatoid Arthritis Treatment

for Rheumatoid Arthritis

Sponsor: XBiotech, Inc.

Sex: All·Age: 18+

Code: NCT06590090·Phase 2

Phase 1b/2 Study of IV Sarilumab in Adult With RA

for Rheumatoid Arthritis

2 sites incl. Hollywood

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT07704580·Phase 1, Phase 2

Apply to this trial

Intra-Articular Adelmidrol 2%/Hyaluronic Acid 1% With or Without m/umPEA, in Knee Pain Due to Joint Degeneration.

for Degenerative Joint Disease of Knee

Sponsor: Universita di Verona

Sex: All·Age: 40+

Code: NCT07680101

Immun4Cure Cohort of Autoimmune Diseases

for Rheumatoid Arthritis

Sponsor: University Hospital, Montpellier

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07515638

Apply to this trial

Faecal Microbiota Transplantation in Patients With Refractory Rheumatoid Arthritis

for Rheumatoid Arthritis

Sponsor: Peking Union Medical College Hospital

Sex: All·Age: 18 - 65

Code: NCT07639177·Phase 2

An Extension Study to Assess Long-Term Safety and Efficacy of Afimkibart in Participants With Rheumatoid Arthritis

for Rheumatoid Arthritis

1 site in Tomball

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT07620392·Phase 2

Apply to this trial

Tdose Binding and Tocilizumab

for Rheumatoid Arthritis

Sponsor: Centre Hospitalier Universitaire de Nice

Sex: All·Age: 18+

Code: NCT07582185·Phase 4

Serum Anti-PCOLCE as Novel Diagnostic Biomarker in Rheumatoid Arthritis With Emphasis on Seronegative Patients.

for Rheumatoid Arthritis

Sponsor: Assiut University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07129837

Disulfiram in Rheumatoid Arthritis

for Rheumatoid Arthritis

1 site in Oklahoma City

Sponsor: University of Oklahoma

Sex: All·Age: 18 - 75

Code: NCT07534332·Phase 2

A Study to Assess Adverse Events, How the Drug Moves Through the Body and Effectiveness of Intravenous Infusions and Subcutaneous Injections of ABBV-519 in Adult Participants With Systemic Lupus Erythematosus (SLE) or Rheumatoid Arthritis (RA)

for Systemic Lupus Erythematosus

9 sites incl. Anniston

Sponsor: AbbVie

Sex: All·Age: 18 - 75

Code: NCT07607964·Phase 1

Apply to this trial

Desloratadine as Adjunct Therapy for Rheumatoid Arthritis

for Rheumatoid Arthritis (RA)

Sponsor: Horus University

Sex: All·Age: 18 - 60

Code: NCT07632872·Phase 2

Apply to this trial

Effect of Roflumilast as Add-On Therapy in Rheumatoid Arthritis

for Rheumatoid Arthritis

Sponsor: Horus University

Sex: All·Age: 18 - 60

Code: NCT07632846·Phase 2

Apply to this trial

Exploratory Clinical Study of Anti-CD19/BCMA Universal CAR-T Cell Injection for the Treatment of Refractory Autoimmune Diseases

for Rheumatoid Arthritis

Sponsor: The First Affiliated Hospital with Nanjing Medical University

Sex: All·Age: 18 - 70

Code: NCT07558850

Apply to this trial

Phase IIb Clinical Study to Assess the Efficacy and Safety of GenSci120 Injection in Patients With Moderately to Severely Active RA Who Have an Inadequate Response to at Least One DMARD

for Rheumatoid Arthritis

Sponsor: Changchun GeneScience Pharmaceutical Co., Ltd.

Sex: All·Age: 18 - 70

Code: NCT07423533·Phase 2

Apply to this trial

Effect of Roflumilast and Desloratadine as Add-On Therapy in Patients With Rheumatoid Arthritis

for Rheumatoid Arthritis

Sponsor: Horus University

Sex: All·Age: 18 - 60

Code: NCT07566351·Phase 2

Apply to this trial

The SetPoint System Safety & Performance Post-Approval Study

for Rheumatoid Arthritis

Sponsor: SetPoint Medical Corporation

Sex: All·Age: 22+

Code: NCT07489326

A Study to Assess the Safety and Tolerability of SR-878 in Patients With Rheumatoid Arthritis

for Rheumatoid Arthritis

Sponsor: SciRhom GmbH

Sex: All·Age: 18 - 60

Code: NCT07433335·Phase 1

Apply to this trial

Venlafaxine as Adjunct Therapy in Rheumatoid Arthritis

for Rheumatoid Arthritis

Sponsor: Ain Shams University

Sex: All·Age: 18+

Code: NCT07497282·Phase 2

Ultrasound Neuroimmune Modulation in Adults With Rheumatoid Arthritis

for Rheumatoid Arthritis

3 sites incl. Colleyville

Sponsor: Surf Therapeutics

Sex: All·Age: 18+

Code: NCT07293871

Apply to this trial

Efficacy and Safety of Ivarmacitinib Monotherapy in the Treatment of csDMARDs-IR Rheumatoid Arthritis

for Rheumatoid Arthritis

Sponsor: Tongji Hospital

Sex: All·Age: 18 - 75

Code: NCT07452445·Phase 4

Efficacy and Safety of Telitacicept Combined With Baricitinib for Refractory Rheumatoid Arthritis

for Telitacicept

Sponsor: Zhejiang Provincial People's Hospital

Sex: All·Age: 18 - 85

Code: NCT07491016

Apply to this trial

A Study to Evaluate the Safety, Tolerability, and Drug Levels of BMS-986454 in Participants With Rheumatoid Arthritis

for Rheumatoid Arthritis

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18 - 65

Code: NCT07171983·Phase 1

Apply to this trial

Exploratory Clinical Study on the Safety and Efficacy of Anti- CD19/BCMA U CAR-T Cell Injection for the Treatment of Relapsed/Refractory Autoimmune Diseases

for Autoimmune Diseases

Sponsor: Changhai Hospital

Sex: All·Age: 18 - 70

Code: NCT07246096·EARLY_Phase 1

Apply to this trial

A Clinical Study of MK-1045 in People With Lupus or Rheumatoid Arthritis (MK-1045-004)

for Systemic Lupus Erythematosus

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18 - 75

Code: NCT07363590·Phase 1

Apply to this trial

"Effect of Vitamin E (α-Tocopherol) on Clinical Activity and Inflammation in Rheumatoid Arthritis"

for Rheumatoid Arthritis

Sponsor: University of Guadalajara

Sex: Female·Age: 18+

Code: NCT06915701·Phase 2, Phase 3

Apply to this trial

A Study of LY4298445 in Healthy Participants and Participants With Systemic Lupus Erythematosus (SLE) or Rheumatoid Arthritis (RA)

for Healthy

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT07276958·Phase 1

Apply to this trial

Baricitinib Effects on Procoagulant State in Rheumatoid Arthritis

for Rheumatoid Arthritis

Sponsor: Tanta University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07357649·Phase 4

Improving Hypertension Control in Rheumatoid Arthritis

for Hypertension

1 site in Durham

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT05760898

Apply to this trial

A Study of AZD0120 in Autoimmune Diseases

for Systemic Sclerosis

8 sites incl. Tucson

Sponsor: AstraZeneca

Sex: All·Age: 18 - 75

Code: NCT07295847·Phase 1

Apply to this trial

Comparison Between JAK Inhibitors and Traditional Treatment of Rheumatoid Arthritis

for Rheumatoid Arthritis

Sponsor: Assiut University

Sex: All·Age: 18 - 60

Code: NCT07272850

A Study to Investigate Efficacy and Safety of AZD1163 in Participants With Rheumatoid Arthritis

for Rheumatoid Arthritis

22 sites incl. Glendale

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07276581·Phase 2

Apply to this trial

Major Adverse Cardiovascular Events (MACE) in Rheumatoid Arthritis Patient With Moderate to Severe Disease Activity Treated With Tofacitinib and Statins vs TNF Inhibitors: TOFSTAT CLINICAL TRIAL

for Rheumatoid Arthritis

Sponsor: Shaikh Zayed Hospital, Lahore

Sex: All·Age: 50 - 85

Code: NCT07554820·Phase 4

Apply to this trial

A Study to Assess the Efficacy and Safety of RO7790121 in Participants With Moderate to Severe Rheumatoid Arthritis Who Have Not Responded to or Who Cannot Tolerate Tumor Necrosis Factor (TNF) and/or Janus Kinase (JAK Inhibitors)

for Rheumatoid Arthritis

12 sites incl. Peoria

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT07137598·Phase 2

Apply to this trial

Study Evaluating Safety, Tolerability, PK/PD of Surovatamig in Adult RA or SLE Participants

for Rheumatoid Arthritis

4 sites incl. Fullerton

Sponsor: AstraZeneca

Sex: All·Age: 18 - 65

Code: NCT07201558·Phase 1

Apply to this trial

Creating Health Course Study for People With Rheumatological Conditions and Mood Disorders

for Rheumatoid Arthritis

1 site in Iowa City

Sponsor: Terry L. Wahls

Sex: All·Age: 18 - 100

Code: NCT07180537

Apply to this trial

Efficacy of Resistance Exercise and an Anti-Inflammatory Diet on Pain, Disease Activity, Functional Status, and Quality of Life in Patients With Rheumatoid Arthritis

for Rheumatoid Arthritis

Sponsor: Berra Yamuç Tanrıöğen

Sex: All·Age: 18+

Code: NCT07262112

EACVI Study on Multimodality Cardiovascular Imaging of Inflammatory Cardiovascular Diseases

for Myocarditis

Sponsor: Assistance Publique - Hôpitaux de Paris

Sex: All·Age: 18+

Code: NCT07077304

Apply to this trial

EMPHASYS Cup Positioning in THA With Non-Invasive Navigation (Velys Hip Navigation (VHN))

for Osteoarthritis

5 sites incl. Sacramento

Sponsor: DePuy Orthopaedics

Sex: All·Age: 21+

Code: NCT06631638

Apply to this trial

Electromagnetic Immunotherapy Mapping and Cytokine Forecasting Study (QSIT)

for Systemic Lupus Erythematosus

1 site in New York

Sponsor: Truway Health, Inc.

Sex: All·Age: All ages

Code: NCT07221565·Phase 1, Phase 2

A Phase 1b Open-label Study to Evaluate Safety of Plamotamab in Participants With Rheumatoid Arthritis

for Rheumatoid Arthritis

Sponsor: Xencor, Inc.

Sex: All·Age: 18+

Code: NCT07230353·Phase 1

Apply to this trial

Study of LFD-200 in Healthy Adults and Adults With Moderate to Severe Rheumatoid Arthritis

for Rheumatoid Arthritis

Sponsor: Lifordi Immunotherapeutics, Inc.

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT07207954·Phase 1

Apply to this trial

Novel Biomarkers in Assessment of Interstitial Lung Disease Associated With Rheumatoid Arthritis Patients

for Rheumatoid Arthritis

Sponsor: Assiut University

Sex: All·Age: 18+

Code: NCT07003451

Triosephosphate Isomerase Level in Relation to Rheumatoid Aerthritis Activity and Structural Damage

for Rheumatoid Arthritis

Sponsor: Assiut University

Sex: All·Age: 18 - 50

Code: NCT07105566

Trauma-Informed Intervention for Rheumatoid Arthritis on Blackfeet Nation

for Rheumatoid Arthritis

Sponsor: Blackfeet Community College

Sex: All·Age: 18+

Code: NCT06472544

Clinical Trial of Huoluo Pills Combined With Iguratimod Tablets in the Treatment of Rheumatoid Arthritis

for Rheumatoid Arthritis

Sponsor: Wangjing Hospital, China Academy of Chinese Medical Sciences

Sex: All·Age: 18 - 70

Code: NCT07115641

Assessment of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Subcutaneous Injections of GenSci120 in Healthy Adult Participants in China.

for Rheumatoid Arthritis

Sponsor: Changchun GeneScience Pharmaceutical Co., Ltd.

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT07040930·Phase 1

Apply to this trial

A Study With CIT-013 in RA Patients

for Rheumatoid Arthritis

Sponsor: Citryll BV

Sex: All·Age: 18+

Code: NCT06567470·Phase 2

Apply to this trial

Targeted Remotely-delivered Anti-inflammatory Interventions With Exercise for Rheumatoid Arthritis

for Rheumatoid Arthritis

1 site in Durham

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT06841562

Apply to this trial

A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid Arthritis

for Rheumatoid Arthritis

56 sites incl. Peoria

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT06972446·Phase 2

Apply to this trial

Post-Market Clinical Follow-Up (PMCF) Study Evaluating the Safety and Efficacy of Tıpmed™ Shoulder Prosthesis System

for Glenohumeral Osteoarthritis

Sponsor: TIPMED Medical Device Manufacturing Ltd. Co.

Sex: All·Age: 18+

Code: NCT07678034

Apply to this trial

The Role of Cytokines and Regulatory T Lymphocytes in Migraine Pathophysiology.

for Migraine Disorders

Sponsor: University Hospital, Clermont-Ferrand

Sex: Female·Age: 18 - 50·Accepts healthy volunteers

Code: NCT06426316

Apply to this trial

Pentoxifylline as Anti-Inflammatory in Patients With Rheumatoid Arthritis

for Rheumatoid Arthritis

Sponsor: Tanta University

Sex: All·Age: 18 - 70

Code: NCT06998628·Phase 2

Apply to this trial

Efficacy and Safety of Telitacicept Combined With Tofacitinib for Refractory Rheumatoid Arthritis

for Telitacicept

Sponsor: Zhejiang Provincial People's Hospital

Sex: All·Age: 18 - 85

Code: NCT06979271

Apply to this trial

An Exploratory Clinical Study of CD19 CAR NK Cells for the Treatment of Refractory Antisynthetase Antibody Syndrome and Rheumatoid Arthritis

for Antisynthetase Syndrome

Sponsor: The First Affiliated Hospital with Nanjing Medical University

Sex: All·Age: 18 - 70

Code: NCT06613490·EARLY_Phase 1

Apply to this trial

Early Clinical Study of UTAA91 Injection for the Treatment of Relapsed/Refractory Autoimmune Diseases

for Systemic Lupus Erythematosus

Sponsor: PersonGen BioTherapeutics (Suzhou) Co., Ltd.

Sex: All·Age: 18+

Code: NCT06970951·EARLY_Phase 1

Study of GS-0151 in Participants With Rheumatoid Arthritis

for Rheumatoid Arthritis

18 sites incl. Anniston

Sponsor: Gilead Sciences

Sex: All·Age: 18 - 75

Code: NCT06902519·Phase 1

Apply to this trial

Nerve Conduction Study for Assessment of Peripheral Neuropathy in Rheumatoid Arthritis Patients on the Janus Kinase Inhibitor Baricitinib

for Rheumatoid Arthritis

Sponsor: Sohag University

Sex: All·Age: 18 - 65

Code: NCT06977035

Apply to this trial

Rheumatoid arthritis clinical trials — common questions

Are rheumatoid arthritis clinical trials free to join?

Yes. Participating in a rheumatoid arthritis clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a rheumatoid arthritis clinical trial?

Each rheumatoid arthritis study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a rheumatoid arthritis trial near me?

Use the location controls above. We'll show recruiting rheumatoid arthritis trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many rheumatoid arthritis trials are recruiting right now?

We're currently tracking roughly 49 recruiting rheumatoid arthritis trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Rheumatoid arthritis trials by city

Aurora, CO Birmingham, AL Oklahoma City, OK Omaha, NE Sacramento, CA San Francisco, CA Ann Arbor, MI Denver, CO Fullerton, CA Gainesville, FL Hollywood, FL La Jolla, CA

Related specialties

Rheumatology Autoimmune disease Musculoskeletal disorders