Ultrasound and Withdrawal of Biological DMARDs in Rheumatoid Arthritis

Sponsor
Medical University of Graz
Study ID
NCT01602302
Phase
PHASE4
Status
Terminated

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 90 Years
Healthy Volunteers
Not accepted

Interventions

Study Details

biological DMARDs may be stopped in Rheumatoid Arthritis (RA) patients treated with a combination of synthetic DMARD plus bDMARDs which are in persistent clinical remission. The research question of this study is, whether musculoskeletal sonography is a useful biomarker predicting a disease flare after cessation of bDMARD therapy.

Key Dates

Start date
Jun 30, 2012
Status verified
Nov 2020
Primary completion
Nov 19, 2020
Completion
Nov 19, 2020

Study Design

Enrollment
40 participants (actual)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: single arm ( bDMARD withdrawal )
    single arm (bDMARD withdrawal)

Primary Outcome Measure

PD-signals predict relapse at week 16 [ Time Frame: 16 weeks ]

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