Combination Rucaparib With Nivolumab in Small Cell Lung Carcinoma
Part of paid clinical trials in Lexington, Kentucky.
- Sponsor
- Zhonglin Hao
- Study ID
- NCT03958045
- Phase
- PHASE2
- Status
- Completed
Conditions
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - N/A
- Healthy Volunteers
- Not accepted
Interventions
- Rucaparib and Nivolumab — COMBINATION_PRODUCTRucaparib (600mg BID) and Nivolumab (480mg IV q4 wk)
Study Details
The purpose of this study is to evaluate survival and response rate of the combination rucaparib and nivolumab as maintenance therapy in platinum-sensitive small cell lung carcinoma.
Key Dates
- Start date
- Sep 4, 2019
- Status verified
- Oct 2024
- Primary completion
- Nov 15, 2022
- Completion
- Nov 15, 2022
Study Design
- Enrollment
- 33 participants (actual)
- Allocation
- NA
- Intervention model
- SINGLE_GROUP
- Primary purpose
- TREATMENT
Arms
- Experimental: Patients with Stage IV SCLCPatients with extensive stage (IV) SCLC (small cell lung cancer)
Primary Outcome Measure
Progression Free Survival [ Time Frame: 0-2 years ]
Locations (1)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| Markey Cancer Center, University of Kentucky | Lexington | Kentucky | 40536 | - |
Find similar trials in Lexington, KY
By condition
By specialty
By research site
Related Studies
- Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid TumorsPHASE1 · Recruiting · SystImmune Inc. · Beverly Hills, California
- A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung CancerPHASE3 · Recruiting · Daiichi Sankyo · Springdale, Arkansas
- A Phase 1 Dose Escalation Study of ZG006 in Patients With Small Cell Lung CancerPHASE1 · Recruiting · Suzhou Zelgen Biopharmaceuticals Co.,Ltd · Orange, California
- A Study to Evaluate the Optimal Dose, Adverse Events and Change in Disease Activity of Intravenous ABBV-706 in Combination With Atezolizumab Versus Standard of Care as First-Line Treatment in Adult Participants With Previously Untreated Extensive Stage Small Cell Lung CancerPHASE2 · Recruiting · AbbVie · New Haven, Connecticut