A Specific Probiotic in thE MOdulation of Gut Microbiota of patieNts With Mild-to-modErate Ulcerative Colitis

Sponsor
Catholic University of the Sacred Heart
Study ID
NCT07724990
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 80 Years
Healthy Volunteers
Not accepted

Interventions

  • For a bipsies — DIAGNOSTIC_TEST
    For the collection of a few additional biopsies
  • rectal administration — DIETARY_SUPPLEMENT
    rectal administration of a specific probiotic

Study Details

Probiotics are live microorganisms that provide health benefits when consumed in sufficient amounts. Traditional probiotics, mainly from the Lactobacillus and Bifidobacterium genera, originate from fermented foods or the human gut and are widely used in supplements. Although considered safe and easy to produce, they are not specifically designed to treat diseases, and no official health claims have been approved by EFSA. Advances in microbiome research have led to the discovery of Next-Generation Probiotics (NGPs), which are newly identified gut microbes associated with health and offer promising therapeutic potential despite lacking a long history of safe use.

Key Dates

First listed
Jul 24, 2026
Start date
May 14, 2025
Status verified
Jul 2026
Primary completion
Sep 14, 2026
Completion
May 14, 2027

Study Design

Enrollment
20 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC

Arms

  • Experimental: Type of patients
    patients with UC and CD

Primary Outcome Measure

Evaluate the effect of rectal administered a specific probiotic in Rectal mucosal healing [ Time Frame: 1 year ]

Central Contacts

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