A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight

Part of paid clinical trials in San Antonio, Texas.

Sponsor
Eli Lilly and Company
Study ID
NCT07738614
Phase
PHASE1
Status
Not Yet Recruiting

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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 65 Years
Healthy Volunteers
Accepted

Interventions

  • Eloralintide — DRUG
    Administered SC
  • Placebo — DRUG
    Administered SC
  • Acetaminophen — DRUG
    Administered Oral Solution

Study Details

The main purpose of this study is to find out how significantly Eloralintide slows stomach emptying in participants who are overweight or obese. For each participant, the study will last approximately 21 weeks and will include 2 overnight stays in the clinical research unit (CRU) lasting between 4 and 8 days. There will be 13 other visits.

Key Dates

First listed
Jul 31, 2026
Start date
Jul 31, 2026
Status verified
Jul 2026
Primary completion
Dec 31, 2026
Completion
Dec 31, 2026

Study Design

Enrollment
56 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Eloralintide Cohort 1
    Eloralintide administered subcutaneously (SC)
  • Experimental: Eloralintide Cohort 2
    Eloralintide administered SC
  • Experimental: Eloralintide Cohort 3
    Eloralintide administered SC
  • Experimental: Eloralintide Cohort 4
    Eloralintide administered SC
  • Placebo Comparator: Placebo
    Placebo administered SC

Primary Outcome Measure

Acetaminophen Area Under the Concentration Versus Time Curve (AUC) [ Time Frame: Baseline to Day 65 ]

Central Contacts

  • Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559) or
    1-317-615-4559
    [email protected]
  • Physicians interested in becoming principal investigators please contact
    [email protected]

Locations (1)

FacilityCityStateZIPSite coordinators
ICON Early Phase ServicesSan AntonioTexas78209
210-225-5437
Chinonye Ogbonnaya-Odor (PRINCIPAL_INVESTIGATOR)

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By condition
Obesity / overweight
By specialty
EndocrinologyMetabolic healthWeight loss
By research site
ICON Early Phase Services· San Antonio, TX

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