A Phase III Study to Evaluate the Efficacy and Safety of Petrelintide in Participants With Overweight or Obesity and Type 2 Diabetes

Part of paid clinical trials in Los Angeles, California.

Sponsor
Hoffmann-La Roche
Study ID
NCT07843485
Phase
PHASE3
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Petrelintide — COMBINATION_PRODUCT
    Petrelintide will be administered subcutaneously (SC) using a drug-device combination product.
  • Placebo — COMBINATION_PRODUCT
    Petrelintide-matching placebo will be administered SC using a drug-device combination product.

Study Details

This study will evaluate the efficacy and safety of petrelintide compared with placebo, in conjunction with a reduced-calorie diet and increased physical activity, for weight management in participants living with overweight or obesity and with Type 2 Diabetes (T2D).

Key Dates

First listed
Sep 28, 2026
Start date
Sep 30, 2026
Status verified
Oct 2026
Primary completion
Oct 20, 2028
Completion
Jan 19, 2029

Study Design

Enrollment
600 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Petrelintide
  • Placebo Comparator: Placebo

Primary Outcome Measure

Percentage Change in Body Weight from Baseline [ Time Frame: From Baseline to Week 64 ]

Central Contacts

  • Reference Study ID Number: CC46369 https://forpatients.roche.com/No attachments to email below.
    888-662-6728 (U.S. and Canada)
    [email protected]
  • Fastest Response: use the inquiry form. https://www.gene.com/contact-us/submit-medical-inquiry

Locations (2)

FacilityCityStateZIPSite coordinators
Institute for Metabolic Research Los AngelesLos AngelesCalifornia90015-
Manassas Clinical Research CenterManassasVirginia20110-

Find similar trials in Los Angeles, CA

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Type 2 diabetes trialsEndocrinology trialsMetabolic health trialsWeight loss trials
By condition
Type 2 diabetes
By specialty
EndocrinologyMetabolic healthWeight loss
By research site
Institute for Metabolic Research Los Angeles· Los Angeles, CAManassas Clinical Research Center· Manassas, VA

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