Heart disease Clinical Trials in Aurora, CO
As of July 2026, 36 paid clinical trials are recruiting for Heart disease in Aurora, Colorado. Heart disease research tests new drug therapies, device-based interventions, and lifestyle programs for heart failure, atrial fibrillation, hypertension, and coronary disease — including therapies that reduce hospitalization and cardiovascular death. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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36 clinical trials for Heart disease
·Clear filters·↓ Download CSVA Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
A Study of Assessment on Safety and Effectiveness of BWI Pulsed Field Ablation With OMNYPULSE Catheter for the Treatment of Paroxysmal Atrial Fibrillation (PAF)
Global Paradise System US Post Approval Study
A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy
Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)
A Study of VARIPULSE Catheter in Participants With Persistent Atrial Fibrillation Undergoing Pulmonary Vein and Superior Vena Cava Isolation
A Study Assessing Long-Term Safety and Effectiveness in Treatment Management of Atrial Fibrillation With VARIPULSE Catheter System
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
Starlight Cardiovascular Lifeline Ductus Arteriosus Stent IDE Study
The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG
Anticoagulation in ICH Survivors for Stroke Prevention and Recovery
Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
Studying the Presence of CFRD Complications With Thoughtful Recruitment (SPeCTRuM)
Implementation and Interaction of Clinician And Patient-facing Tools Aiming to Intensify Neurohormonal Medicines for Heart Failure
Safety and Efficacy of Workflows of High Volume Single Operators in a LAAO Device Implant Procedural Day
Colorado Community Engagement Alliance
Equol and Vascular Function in Women With Chronic Kidney Disease
NightWare and Cardiovascular Health in Veterans With PTSD
Supporting VETerans With Kidney Disease Through Food As Medicine
Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease
A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
Digital Health Physical Activity Program for Older Family Care Partners of Patents With Heart Failure
Efficacy and Mechanisms of Dapagliflozin in Promoting Kidney Function and Cardiovascular Health in Kidney Transplant Recipients
MANATEE-T1D: Metformin ANd AutomaTEd Insulin Delivery System Effects on Renal Vascular Resistance, Insulin Sensitivity, and Cardiometabolic Function in Youth With Type 1 Diabetes
Effect of Alkali Therapy on Vascular and Graft Function in Kidney Transplant Recipients
Structural Conditions and Health After Release From Prison
Inspiratory Muscle Strength Training in Chronic Kidney Disease
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients With Heart Failure Who Are Intolerant or Not Eligible for Treatment With Steroidal Mineralocorticoid Receptor Antagonists
Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products
Product Surveillance Registry
About research studies in Aurora
Aurora has approximately 1,101 recruiting research studies across a wide range of therapeutic areas. Colorado hosts the University of Colorado Anschutz Medical Campus, National Jewish Health, and Children's Hospital Colorado, with strong programs in pulmonology, oncology, and cardiovascular research.
Top Research Study Locations in Aurora
Researchers run research studies in Aurora, CO at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Children's Hospital Colorado | High Grade Glioma, Diffuse Intrinsic Pontine Glioma, Acute Myeloid Leukemia | 182 |
| University of Colorado Anschutz Medical Campus | Obesity, Cannabis Use Disorder, Overweight and Obesity | 108 |
| University of Colorado | Parkinson Disease, Acute Myeloid Leukemia, Barrett Esophagus | 90 |
| UCHealth University of Colorado Hospital | Metastatic Malignant Solid Neoplasm, Stage IV Lung Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 55 |
| University of Colorado Hospital | Acute Kidney Injury, Carcinoma, Non-Small-Cell Lung, Lung Cancer | 55 |
| University of Colorado Cancer Center | Breast Cancer, Advanced Solid Tumor, Melanoma | 36 |
| University of Colorado Denver | Contraception, Depression, Anxiety, Diabetes | 32 |
| Rocky Mountain Regional VA Medical Center, Aurora, CO | Aging, Chronic Obstructive Pulmonary Disease, Chronic Pain | 31 |
| Rocky Mountain Cancer Centers-Aurora | Malignant Solid Neoplasm, Melanoma, Anatomic Stage IV Breast Cancer AJCC v8 | 24 |
| University of Colorado Anschutz | Acanthamoeba Keratitis, Adiposity, Alcohol Use Disorder | 21 |
| Childrens Hospital Colorado | Hypochondroplasia, Adolescent Obesity, Anger | 17 |
| Rocky Mountain Regional VA Medical Center | Hypertension, Malignant Solid Neoplasm, Melanoma | 15 |
| Children's Hospital of Colorado | Cystic Fibrosis, Muscular Atrophy, Spinal, Abnormal Glucose Tolerance | 14 |
| The Medical Center of Aurora | Chronic Lymphocytic Leukemia, Malignant Solid Neoplasm, Melanoma | 12 |
| GSK Investigational Site | HIV Infections, Gastrointestinal Neoplasms, Irritable Bowel Syndrome | 10 |
| University of Colorado - Anschutz Medical Campus | Aging, Hypertension, Interstitial Lung Disease | 10 |
| Rocky Mountain Cancer Centers | Breast Cancer, Higher-risk Myelodysplastic Syndromes, Leukemia, Myeloid, Acute | 9 |
| University of Colorado School of Medicine | Cervical Cancer, Choline Deficiency, Diffuse Large B Cell Lymphoma (DLBCL) | 7 |
| University of Colorado, Denver | Arrhythmogenic Right Ventricular Cardiomyopathy, Arteriovenous Malformations, Cannabis Smoking | 6 |
| Rocky Mountain Cancer Centers, LLP | Colorectal Neoplasms, Advanced/Metastatic Urothelial Cancer, B-Cell Non-Hodgkins Lymphoma | 6 |
| Clinical Trial Site | Breast Cancer, ER Positive Breast Cancer, HER2 Negative Breast Carcinoma | 5 |
| Colorado Children's Hospital | Anesthesia, Caregiver Stress, Children | 5 |
| University of Colorado Denver Anschutz Medical Campus | IUGR, Pregnancy, Frostbite | 5 |
| University of Colorado Hospital - Anschutz Cancer Pavilion | Advanced Liver Cancers, Advanced Melanoma, Advanced Or Metastatic Merkel Cell Carcinoma | 5 |
| University of Colorado, Anschutz Medical Campus | Advanced Melanoma, Amputation, Bone Anchored Devices | 5 |
Active & Upcoming Studies in Aurora (2026)
Recruiting trials in Aurora grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (313 active studies)
- Trial to Evaluate an Educational Video Series for Women in Breast Cancer Treatment · University of Colorado, Denver
- Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma · Phase 2 · University of Colorado, Denver
Diabetes & metabolic (87 active studies)
- Digitally Enhanced Cognitive-Behavioral Therapy · Colorado State University
- PRISE (Personalized Response and Immunologic Surveillance of Endogenous C-Peptide Preservation in New, Recent, and Established Onset Type 1 Diabetes Treated With Human Anti-Thymocyte Globulin [h-ATG]) Study · Phase 3 · University of Florida
Neurology & pain (70 active studies)
- Personalizing Veteran Pain Care: Adapting Coaching Interventions to Support Maintenance of Self-Care · Phase 1 · VA Office of Research and Development
- Headache Education and Awareness vs. Daily Mindfulness Strategies - Understanding Pain · University of Colorado, Denver
Cardiovascular (63 active studies)
- A Study of VARIPULSE Catheter in Participants With Persistent Atrial Fibrillation Undergoing Pulmonary Vein and Superior Vena Cava Isolation · Biosense Webster, Inc.
- Tiprelestat Versus Placebo When Added to Standard of Care for the Treatment of Pulmonary Arterial Hypertension (PAH) · Phase 2 · Stanford University
Pediatric (33 active studies)
- A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction · Phase 3 · Bayer
- Asthma Ctrl SMART Trial · Children's Hospital Medical Center, Cincinnati
Mental health & behavior (20 active studies)
- Digitally Enhanced Cognitive-Behavioral Therapy · Colorado State University
- Multi-Site Trial of Tirzepatide for Smoking Cessation · Phase 2 · University of Southern California
HIV / STI (16 active studies)
- A Study to Evaluate the Safety and Antiviral Activity of Two Human Monoclonal Antibodies (VRC07-523LS and PGT121.414.LS) During Analytic Treatment Interruption in Participants Living With HIV Who Initiated ART During Acute/Early HIV-1 Infection · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
- Liver Transplantation From Donors With HIV: Impact on Opportunistic Infections, Cancer, and Long-Term Outcomes (Expanding HOPE Liver) · Johns Hopkins University
Vaccines (8 active studies)
Eye & vision (5 active studies)
- A Study to Assess Adverse Events and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo Approaches in Adult Participants With Glaucoma · Phase 3 · AbbVie
- A Phase 1/2, First-in-Human Dose Escalation/Expansion Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of a Subretinal Injection of SB-007 in Subjects With Stargardt Disease (STGD1) · Phase 1, Phase 2 · Splice Bio
Common conditions studied in Aurora
- Breast Cancer (22 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Obesity (18 active studies). Obesity trials evaluate GLP-1 and GIP receptor agonists, novel metabolic drugs, and combined lifestyle interventions for sustainable weight loss.
- Heart Failure (13 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
- Melanoma (13 active studies). Melanoma trials test immune checkpoint inhibitors, adoptive cell therapies, and BRAF/MEK targeted combinations in both early and metastatic disease.
- Colorectal Cancer (12 active studies). Colorectal cancer trials explore novel chemotherapy combinations, targeted agents, and immunotherapy for microsatellite-instability-high tumors.
- Type 1 Diabetes (12 active studies). Type 1 diabetes research investigates immune-modulating therapies, stem cell–derived islet replacement, and closed-loop insulin delivery systems.
Leading research sponsors in Aurora
- University of Colorado, Denver
- National Cancer Institute (NCI)
- VA Office of Research and Development
- Children's Oncology Group
- AstraZeneca
Local regulations and guidelines
Clinical trials in Colorado are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Colorado trials are additionally subject to the Colorado Privacy Act (CPA), which adds consumer data-protection requirements to federal baseline standards.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Aurora. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Aurora
Hipa.ai aggregates every recruiting study in Aurora from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Aurora?
There are approximately 1,101 recruiting clinical trials in Aurora, Colorado listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Aurora pay participants?
Most recruiting trials in Aurora compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Aurora?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Aurora?
The most common conditions under active study in Aurora include Breast Cancer (22), Obesity (18), Heart Failure (13), Melanoma (13), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Aurora?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Aurora on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Aurora?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Aurora?
Recruiting research sites in Aurora include Children's Hospital Colorado, University of Colorado Anschutz Medical Campus, University of Colorado, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Aurora right now?
The largest active categories in Aurora are Cancer & tumors (313), Diabetes & metabolic (87), Neurology & pain (70). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.